Therapeutics News and Research

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Novel approach to drug repurposing incorporates two-stage prediction and machine learning

A new study presents a novel approach to drug repurposing that incorporates two-stage prediction and machine learning.

7 Jun 2022

De novo-designed mini-protein against SARS-CoV-2

Researchers characterized truncated forms of LCB1, a de novo-designed mini-protein, against SARS-CoV-2.

7 Jun 2022

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

A new study, led by researchers from the University of California, Irvine, reveals the unique cell-to-cell communication networks that can perpetuate inflammation and prevent repigmentation in patients with vitiligo disease.

7 Jun 2022

Etiologies of liver cancer are changing and the prognosis is mixed, study says

The primary causes of liver cancer are well known: viral (hepatitis B and C), alcohol and non-alcoholic steatohepatitis (NASH), a condition in which fat builds up in the liver, resulting in chronic inflammation and damage.

7 Jun 2022

Post-COVID smell and taste dysfunction associated with better recovery in long-COVID

In a recent study posted to the medRxiv* pre-print server, Austrian researchers performed a multi-cohort analysis to investigate the slow resolution of subjective olfactory dysfunction (OD) and accompanying taste disorder in coronavirus disease 2019 (COVID-19) inpatients and outpatients.

7 Jun 2022

Study says 460k of first million recorded US COVID deaths caused by variants

In a recent research paper posted to the medRxiv* preprint server, scientists from Yale School of Public Health analyzed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-linked deaths in the United States (US).

7 Jun 2022

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

Patients with multiple myeloma who have been treated with a three-drug combination therapy have a growing number of choices for subsequent treatment. Results of a new study led by researchers at Dana-Farber Cancer Institute can help patients and their physicians weigh benefits and risks of each option.

6 Jun 2022

MIT researchers identify components of mucus that can inhibit fungal infections

Candida albicans is a yeast that often lives in the human digestive tract and mouth, as well as urinary and reproductive organs.

6 Jun 2022

Curia Adopts the Berkeley Lights Platform to Expand its Antibody Discovery Capabilities

Berkeley Lights, Inc. (Nasdaq: BLI), a leader in digital cell biology, and Curia, formerly AMRI, a leading contract research, development and manufacturing organization (CDMO), today announced Curia’s adoption of The Beacon® Optofluidic system and workflows from Berkeley Lights to accelerate and expand its antibody-based drug discovery capabilities.

From Bruker Cellular Analysis 6 Jun 2022

The frequency and nature of RNA errors in both SARS-CoV-2 and its vaccine

A recent article demonstrated that SARS-CoV-2 mutants and vaccine variability stem from ribonucleic acid polymerase inaccuracy.

6 Jun 2022

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

Nearly 43% of patients with non-small cell lung cancer (NSCLC) whose lung cancers harbored a specific KRAS mutation responded to the experimental drug adagrasib, and the targeted agent also showed activity against lesions in the brain that metastasized from the lung tumors, according to results of a study led by Dana-Farber Cancer Institute investigators.

3 Jun 2022

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Researchers have discovered the mechanism by which specific immune cells can block breast cancer development and even suppress a developed tumor.

3 Jun 2022

Computer vision tool effectively distinguishes rheumatoid arthritis from osteoarthritis in joint tissue

A new study led by Hospital for Special Surgery investigators in New York City has found that their computer vision tool effectively distinguishes rheumatoid arthritis (RA) from osteoarthritis (OA) in joint tissue taken from patients who underwent total knee replacement (TKR).

3 Jun 2022

A non-coding RNA molecule regulates mitochondrial gene expression in human cells, study shows

A new study published in the journal Cell shows that a non-coding RNA molecule regulates mitochondrial gene expression in human cells.

2 Jun 2022

Multidisciplinary medical team needed to provide care for pregnant women with lupus, study says

A study that includes researchers at Hospital for Special Surgery underscores the importance of a multidisciplinary medical team to counsel and provide care for women with systemic lupus erythematosus, the most common form of lupus, who become pregnant.

2 Jun 2022

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

A large randomized, placebo-controlled clinical trial led by the National Institutes of Health shows that treating adults hospitalized with COVID-19 with infliximab or abatacept - drugs widely used to treat certain autoimmune diseases - did not significantly shorten time to recovery but did substantially improve clinical status and reduce deaths.

2 Jun 2022

MD Anderson and National Resilience launch the Cell Therapy Manufacturing Center

The University of Texas MD Anderson Cancer Center and National Resilience, Inc., today announced the launch of a joint venture, the Cell Therapy Manufacturing Center, to accelerate the development and manufacturing of innovative cell therapies for patients with cancer.

2 Jun 2022

Therapeutics News and Research

Novel approach to drug repurposing incorporates two-stage prediction and machine learning

De novo-designed mini-protein against SARS-CoV-2

Discovery may lead to new treatments to reduce inflammation in vitiligo disease

Etiologies of liver cancer are changing and the prognosis is mixed, study says

Post-COVID smell and taste dysfunction associated with better recovery in long-COVID

Study says 460k of first million recorded US COVID deaths caused by variants

Three-drug therapy with autologous stem cell transplant improves progression-free survival for multiple myeloma patients

MIT researchers identify components of mucus that can inhibit fungal infections

Curia Adopts the Berkeley Lights Platform to Expand its Antibody Discovery Capabilities

The frequency and nature of RNA errors in both SARS-CoV-2 and its vaccine

Study: Nearly 43% of patients with KRAS-mutated lung cancer respond to experimental drug adagrasib

New immunotherapy mechanism can block spontaneous breast carcinogenesis

Computer vision tool effectively distinguishes rheumatoid arthritis from osteoarthritis in joint tissue

A non-coding RNA molecule regulates mitochondrial gene expression in human cells, study shows

Multidisciplinary medical team needed to provide care for pregnant women with lupus, study says

Immune modulator drugs improved clinical status, reduced deaths among patients hospitalized with COVID-19

MD Anderson and National Resilience launch the Cell Therapy Manufacturing Center

Aerobic exercise amplifies the effects of immunotherapy to reduce pancreatic tumor growth

New HSS study clarifies the clinical manifestations of undifferentiated connective tissue disease

Scientists characterize a novel zoonotic coronavirus in humans

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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