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Genetic differences play a role in prostate cancer disparities

Genetic differences in prostate cells seem to be a root cause of the prostate cancer disparities between African-American men and white men, according to findings presented at the Fourth AACR Conference on The Science of Cancer Health Disparities, held here Sept. 18-21, 2011.

21 Sep 2011

A code beyond DNA: Modified tRNA bases are characteristic of species

Our genetic code consists of four “letters” in the form of the nucleobases in our DNA and RNA. Three letters together form a “word” that are translated into an amino acid by tRNA and combined into proteins. Special markings subdivide the gene into active and inactive regions. A third possible level of information has so far received less attention: the chemical modification of tRNA nucleobases. In the journal Angewandte Chemie Thomas Carell and a team at the University of Munich have now demonstrated that tRNA modification profiles can be used for the characterization of species and the differentiation of pathogenic and nonpathogenic bacterial strains.

20 Sep 2011

Coulter Foundation awards University of Pittsburgh $3.54M grant for translational bioengineering research

The Swanson School of Engineering at the University of Pittsburgh has received a $3.54 million grant from the Wallace H. Coulter Foundation.

17 Sep 2011

GSA's two forthcoming publications focus on pain relief and medication for seniors

To highlight Pain Awareness Month in September, The Gerontological Society of America (GSA) - the nation's largest interdisciplinary organization devoted to the field of aging - is announcing two forthcoming publications focused on pain relief and medication for seniors.

16 Sep 2011

EMBL, five countries sign ELIXIR's Memorandum of Understanding

Today marks an important step for ELIXIR, Europe's emerging research infrastructure for life-science information, as five countries plus the European Molecular Biology Laboratory (EMBL) have signed a Memorandum of Understanding to catalyse the implementation and construction of ELIXIR.

14 Sep 2011

NextBio Enterprise licensed by University of Southern California for research use

NextBio, provider of an innovative platform that enables life science researchers to search, discover, and share knowledge locked within public and proprietary data, announced that the University of Southern California (USC) has licensed NextBio Enterprise for research use by students and faculty. The University plans to promote use of the NextBio research platform campus-wide beginning in August.

12 Sep 2011

Scientists discover new gene mutation responsible for late-onset Parkinson's

Less than two months after publishing findings about a new gene linked to late-onset Parkinson's disease, the same team of scientists at the University of British Columbia and Vancouver Coastal Health Research Institute have discovered another gene responsible for the neurodegenerative disease - providing yet another target for potential treatments.

9 Sep 2011

New application translates foreign-language food menus for English speakers

Researchers have created an application that enables cell phones and other portable devices to translate foreign-language food menus for English speakers and could be used for people who must follow restricted diets for medical reasons.

9 Sep 2011

Researchers discover new genetic defect that can lead to Leigh syndrome

In Leigh syndrome, infants are born apparently healthy only to develop movement and breathing disorders that worsen over time, often leading to death by the age of 3. The problem is that the mitochondria responsible for powering their cells can't keep up with the demand for energy in their developing brains.

7 Sep 2011

UCF, UF receive $5.5 million NIH grant for hemophilia research

At a time when research funding is hard to come by, a University of Central Florida and University of Florida partnership has landed almost $5.5 million in National Institutes of Health highly competitive grants for hemophilia research.

3 Sep 2011

Scientists aim to tackle Hawaii's liver cancer problem with improved detection

Two scientists from the University of Hawaii Cancer Center and The Queen's Medical Center have received a five-year $2.3 million grant from the National Cancer Institute to develop novel methods that can better detect liver cancer through the joint analysis of gene expression and imaging data of the liver.

24 Aug 2011

First international conference on developmental, translational and clinical pharmacogenomics

The first international conference hosted by the University of South Florida College of Pharmacy will focus on ways to improve health care by customizing drug prescribing and treatment based on an individual's genetic makeup.

24 Aug 2011

Canada's Minister of Health announces Strategy for Patient-Oriented Research

Today the Honourable Leona Aglukkaq, Minister of Health announced the Strategy for Patient-Oriented Research (SPOR), a transformative research initiative that places patients at the centre of health care.

24 Aug 2011

Pearl selects TransPerfect's Trial Interactive eTMF solution for clinical development programs

TransPerfect today announced that Pearl Therapeutics has implemented TransPerfect's Trial Interactive electronic Trial Master File (eTMF) solution for the company's clinical development programs.

23 Aug 2011

Spinifex secures AU$6.25 million in expanded Series B funding

Spinifex Pharmaceuticals, an Australian pain drug development company, today announced it has secured a further AU$6.25 million of venture capital investment from GBS Venture Partners Limited, Brandon Capital Partners Pty Limited, Uniseed Management Pty Limited and UniQuest Pty Limited to fund the development of its pain management drug, EMA401.

23 Aug 2011

Crimson announces publication of Japan Medical Device Digest

Crimson Life Sciences, a division of TransPerfect and the world's only ISO 13485 and ISO 14971-certified translation provider, today announced the publication of their Japan Medical Device Digest, a free monthly report that provides English translations of Japanese-language news items.

23 Aug 2011

Canada's Minister of Health to fund 25 policy-relevant research projects across six provinces

In support of the Government of Canada's commitment to strengthening Canada's healthcare system, the Honourable Leona Aglukkaq, Minister of Health, announced today funding for 25 policy-relevant research projects across six provinces.

20 Aug 2011

NIH/NINDS awards AMRI to develop pre-clinical drug candidate for spinal muscular atrophy

AMRI today announced it received a federal contract award from the National Institutes of Health (NIH)/National Institute of Neurological Disorders and Stroke (NINDS) to provide chemistry and other drug discovery technologies in support of NINDS' Medicinal Chemistry for Neurotherapeutics Program (MCNP), part of the NIH Blueprint Neurotherapeutics Network.

19 Aug 2011

Mayo researchers to translate genomic discoveries into tools for individualized medicine

Mayo Clinic researchers will receive more than $3 million in a four-year grant from the National Human Genome Research Institute to translate recent genomic discoveries into tools for individualized medicine. Recent advances in the genetics of heart and blood vessel diseases will be integrated into electronic medical records so doctors can more accurately determine patients' risk of heart attacks, blood vessel diseases and adverse reactions to heart medications.

18 Aug 2011

Study reveals structure of ribosomal assembly intermediate

As part of a joint research effort with the University of Michigan, scientists from the Florida campus of The Scripps Research Institute have for the first time defined the structure of one of the cell's most basic engines, which is required for cell growth, as it assembles from its components.

17 Aug 2011

Translation News and Research

Genetic differences play a role in prostate cancer disparities

A code beyond DNA: Modified tRNA bases are characteristic of species

Coulter Foundation awards University of Pittsburgh $3.54M grant for translational bioengineering research

GSA's two forthcoming publications focus on pain relief and medication for seniors

EMBL, five countries sign ELIXIR's Memorandum of Understanding

NextBio Enterprise licensed by University of Southern California for research use

Scientists discover new gene mutation responsible for late-onset Parkinson's

New application translates foreign-language food menus for English speakers

Researchers discover new genetic defect that can lead to Leigh syndrome

UCF, UF receive $5.5 million NIH grant for hemophilia research

Scientists aim to tackle Hawaii's liver cancer problem with improved detection

First international conference on developmental, translational and clinical pharmacogenomics

Canada's Minister of Health announces Strategy for Patient-Oriented Research

Pearl selects TransPerfect's Trial Interactive eTMF solution for clinical development programs

Spinifex secures AU$6.25 million in expanded Series B funding

Crimson announces publication of Japan Medical Device Digest

Canada's Minister of Health to fund 25 policy-relevant research projects across six provinces

NIH/NINDS awards AMRI to develop pre-clinical drug candidate for spinal muscular atrophy

Mayo researchers to translate genomic discoveries into tools for individualized medicine

Study reveals structure of ribosomal assembly intermediate

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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