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HIV subtype D infected patients more likely to develop dementia

Patients infected with a particular subtype of HIV, the virus that causes AIDS, are more likely to develop dementia than patients with other subtypes, a study led by Johns Hopkins researchers shows. The finding, reported in the September Clinical Infectious Diseases, is the first to demonstrate that the specific type of HIV has any effect on cognitive impairment, one of the most common complications of uncontrolled HIV infection.

28 Aug 2009

NAT gains importance as traditional testing methods become inadequate

An expanding population of bacterial strains that are drug resistant, including methicillin-resistant Staphylococcus aureus (MRSA), will be the most important justification for nucleic acid-based tests (NAT).

28 Aug 2009

ASHG 2009 Annual Meeting to discuss the cutting-edge developments in human genetics and genomics research

The world's top scientists and clinicians in the human genetics field will gather in Honolulu, Hawaii to present their latest research findings at the 59th Annual Meeting of the American Society of Human Genetics, from Tuesday, October 20, through Saturday, October 24, 2009, at the Hawaii Convention Center.

28 Aug 2009

Iowa researchers modify siRNA for impacting targeted cells in cancer treatment

Small interfering RNA (siRNA), a type of genetic material, can block potentially harmful activity in cells, such as tumor cell growth. But delivering siRNA successfully to specific cells without adversely affecting other cells has been challenging.

28 Aug 2009

NIH awards $3.5-million grant to Tay-Sachs Gene Therapy Consortium for research on fatal genetic disorders

In a victory for families who dug into their own pockets to fund new research, the National Institutes of Health has awarded a $3.5-million grant to the Boston-based Tay-Sachs Gene Therapy Consortium to prepare a gene therapy for human clinical trials in a bid to halt the fatal genetic disorder.

28 Aug 2009

NIH panel releases report on the pertinence of family health history information in improving health

Though most Americans are familiar with completing a questionnaire about their family health history when visiting health care providers, an independent panel was convened by the National Institutes of Health this week to critically assess exactly what we know and what we need to learn about how this process relates to improving health.

28 Aug 2009

Abbott to partner with Pfizer to develop a companion diagnostic test for non-small cell lung cancer

Abbott announced today that it has entered into an agreement with Pfizer Inc to develop a molecular diagnostic test intended to screen non-small cell lung cancer (NSCLC) tumors for the presence of gene rearrangements.

28 Aug 2009

CRi's Oosight imaging system used for developing a gene transfer technique to prevent inherited diseases

U.S. researchers using CRi's Oosight(TM) imaging system have developed a gene transfer technique that has potential to prevent inherited diseases passed on from mothers to their children through mutated DNA in cell mitochondria.

28 Aug 2009

H1N1 virus detected in turkeys

The detection of an H1N1 virus in turkeys in Chile raises concern that poultry farms elsewhere in the world could also become infected with the pandemic flu virus currently circulating in humans, FAO said today.

27 Aug 2009

HLA-Cw*0602 gene variation detected as a high risk for psoriasis

A specific genetic region that has been increasingly identified as the strongest genetic link to psoriasis has an even more significant role in the chronic skin disease than has been suspected, University of Utah medical researchers show in a new study.

27 Aug 2009

Affymetrix and Beckman Coulter forge alliance to provide optimized genomic research solutions

Affymetrix, Inc. (Nasdaq: AFFX) and Beckman Coulter, Inc. today announced that they have entered into an agreement to offer researchers co-developed products from the market leaders in microarrays and automated liquid handlers.

From Beckman Coulter Life Sciences - Automation and Genomics 27 Aug 2009

Fluidigm manufactures more than 250 million microscopic NanoFlex valves at its Singapore biochip factory

Fluidigm today announced that its Singapore biochip factory has manufactured and shipped more than 250 million microscopic NanoFlex™ valves. The 250 million valves built into Fluidigm’s integrated fluidic circuits (IFCs) would be equivalent to the number of valves required for all the conventional plumbing – both residential and commercial – in a metropolitan region the size of the San Francisco Bay Area.

27 Aug 2009

New genetic mechanism to control body's fat-building process identified

At a time of alarming increases in obesity and associated diseases -- and fiery debates about the cost of health care -- a UCF research team has identified a new genetic mechanism that controls the body's fat-building process.

27 Aug 2009

Lakewood-Amedex to speed up development of its broad spectrum anti-influenza product into clinical studies

Lakewood-Amedex Inc., (L-A), the anti-infectives biopharmaceutical company developing a unique portfolio of anti-bacterial and anti-viral products including NuBiotics, a novel family of synthetic anti-bacterial compounds, and anti-viral products against hepatitis, HIV and influenza, announced today that it is accelerating development of its broad spectrum anti-influenza product into clinical studies.

27 Aug 2009

Rapid, accurate and cost-efficient testing of DNA with the Nanogap Sensor Array

A novel electronic sensor array for more rapid, accurate and cost-efficient testing of DNA for disease diagnosis and biological research has been developed by scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN).

27 Aug 2009

Nanogap sensor array for ultra-sensitive detection of human DNA

Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. Such tests are done for criminal investigation, disease diagnosis, and other purposes.

27 Aug 2009

Relationship between the CD14 variation and the formation of portal lymphoid aggregates discovered

It is still unknown why the natural history of chronic disease caused by hepatitis C virus (HCV), which currently infects 3% of the world's population, varies from mild in some patients to rapidly progressing in others. Age, sex, alcohol consumption and liver sensitivity to gut-derived bacterial endotoxins, were the early factors defined to enhance the risk of fibrosis progression.

27 Aug 2009

Scientists discover a new way for preventing liver metastases

Scientists in Switzerland have discovered a way to block the growth of human colon cancer cells, preventing the disease from reaching advanced stages and the development of liver metastases. The research, published today in EMBO Molecular Medicine, shows that blocking the so-called Hedgehog-GLI pathway can prevent the growth of tumours, metastatic lesions and cancer stem cells, the cells thought to lie at the root of cancer growth.

27 Aug 2009

Patients with Phenylketonuria face increased risk of developing severe neurological complications

Genetic researchers at Children's Memorial Hospital, Chicago, are aggressively identifying adult patients who suffer from the genetic disorder, Phenylketonuria (PKU), and are presenting those findings at the 11th International Congress of Inborn Errors of Metabolism in San Diego, August 29 through September 2.

26 Aug 2009

Viral polymerase may provide a new therapeutic target for host-adapted avian influenza

Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. The related report by Gabriel et al, "Spread of Infection and Lymphocyte Depletion in Mice Depends on Polymerase of Influenza Virus" appears in the September 2009 issue of the American Journal of Pathology.

26 Aug 2009

Genetic News and Research

HIV subtype D infected patients more likely to develop dementia

NAT gains importance as traditional testing methods become inadequate

ASHG 2009 Annual Meeting to discuss the cutting-edge developments in human genetics and genomics research

Iowa researchers modify siRNA for impacting targeted cells in cancer treatment

NIH awards $3.5-million grant to Tay-Sachs Gene Therapy Consortium for research on fatal genetic disorders

NIH panel releases report on the pertinence of family health history information in improving health

Abbott to partner with Pfizer to develop a companion diagnostic test for non-small cell lung cancer

CRi's Oosight imaging system used for developing a gene transfer technique to prevent inherited diseases

H1N1 virus detected in turkeys

HLA-Cw*0602 gene variation detected as a high risk for psoriasis

Affymetrix and Beckman Coulter forge alliance to provide optimized genomic research solutions

Fluidigm manufactures more than 250 million microscopic NanoFlex valves at its Singapore biochip factory

New genetic mechanism to control body's fat-building process identified

Lakewood-Amedex to speed up development of its broad spectrum anti-influenza product into clinical studies

Rapid, accurate and cost-efficient testing of DNA with the Nanogap Sensor Array

Nanogap sensor array for ultra-sensitive detection of human DNA

Relationship between the CD14 variation and the formation of portal lymphoid aggregates discovered

Scientists discover a new way for preventing liver metastases

Patients with Phenylketonuria face increased risk of developing severe neurological complications

Viral polymerase may provide a new therapeutic target for host-adapted avian influenza

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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