Clinical Trial News and Research

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Understanding how to better prescribe probiotics based on our individual microbiome profiles

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

28 Mar 2023

Clinical trial of ENZAMET shows promising results for men with advanced prostate cancer

A new drug combination for men with advanced prostate cancer has shown sustained increase in survival rates.

28 Mar 2023

New evidence: Fibromyalgia could worsen opioid use disorder

There is new evidence that fibromyalgia, and the chronic pain associated with it, could worsen opioid use disorder.

28 Mar 2023

Pulsed radiofrequency combined with steroid injection leads to better outcomes in patients with sciatica

Researchers found that a minimally invasive procedure combined with epidural steroid injection treatment led to superior pain reduction and disability improvement over one year in patients with sciatica.

28 Mar 2023

New combination therapy shows promising results in some patients with advanced head and neck cancer

A new combination drug treatment showed promising results in patients with pan-refractory, recurrent/metastatic head and neck cancer, according to a study published today in the Journal of Clinical Oncology.

28 Mar 2023

Chemotherapy plus immunotherapy improves outcomes in patients with advanced endometrial cancer

Endometrial cancer, which makes up about 90% of uterine cancers, will be diagnosed in more than 65,000 people in the United States this year.

28 Mar 2023

Surgeons can play an important role in reducing breast cancer disparities

Surgeons can play a key role in reducing breast cancer disparities by increasing their awareness of where disparities exist and having open conversations with their patients about their needs to initiate referrals early on in their care, according to a new collective review article published in the Journal of the American College of Surgeons.

28 Mar 2023

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Providing an overview of the submissions process and examples of U.S. Food and Drug Administration (FDA) applications for Orphan Drug Designation (ODD) and Rare Pediatric Disease Designation (RPDD), a new article can help developers of gene therapies for rare genetic diseases.

27 Mar 2023

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

Sepsis occurs in approximately 1.7 million hospitalizations in the U.S. with in more than a third of hospitalizations resulting in death.

27 Mar 2023

SolasCure announces final closing of GBP 10.9m (c. USD 13.3m) Series B fundraise to advance wound care innovation

SOLASCURE Ltd (SolasCure), a biotechnology company developing a hydrogel containing a recombinant enzyme derived from maggots which aims to accelerate wound debridement, has announced the completion of its GBP 10.9m (c. USD 13.3m) Series B investment round. The funding round was led by Seneca Partners and also included industry veterans, institutional venture and strategic investors, including BRAIN Biotech AG, EVA Pharma, Jonathan Milner, and Wealth Club.

From SolasCure 27 Mar 2023

Intermittent fasting shows potential benefits for obesity treatment and brain-gut-microbiome health

A recent Nutrients journal study by researchers at the David Geffen School of Medicine at the University of California, Los Angeles, has discussed the effects of time-restricted eating on BGM and reviewed its promising effects in obesity treatment.

26 Mar 2023

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

The National Institute of Allergy and Infectious Diseases awarded an up to $16 million contract to Tulane University to bring to phase one clinical trial a nasal spray vaccine university researchers invented to thwart antibiotic-resistant Klebsiella pneumoniae, a leading cause of pneumonia.

24 Mar 2023

Psychological therapy can help provide better quality of life for women with endometriosis

Nearly 10% of Danish women suffer from endometriosis, which can cause serious pelvic pain.

23 Mar 2023

AI-based diagnostic screening system could streamline the diagnosis and treatment of gliomas

Using artificial intelligence, researchers have discovered how to screen for genetic mutations in cancerous brain tumors in under 90 seconds - and possibly streamline the diagnosis and treatment of gliomas, a study suggests.

23 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

Fighting antibiotic-resistant "superbugs" with viruses

The Centers for Disease Control and Prevention warns that the increase in cases of the drug-resistant bacterial infection Shigella could be a predictor of what's to come for other bacteria.

21 Mar 2023

ACTG publishes study to simplify the administration of hepatitis C treatment

The AIDS Clinical Trials Group, the world's largest HIV research network, is announcing the publication of "Perspectives on Adherence from the ACTG 5360 MINMON Trial: A Minimum Monitoring Approach with 12 Weeks of Sofosbuvir/Velpatasvir in Chronic Hepatitis C Treatment" in the journal Clinical Infectious Diseases.

21 Mar 2023

MHRA to introduce a series of new measures for streamlining clinical trial approvals

A series of new measures will be introduced by the Medicines and Healthcare products Regulatory Agency (MHRA) with support from partners to make it faster and easier to gain approval and to run clinical trials in the UK.

21 Mar 2023

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

A new UCLA-led study suggests that advanced genome editing technology could be used as a one-time treatment for the rare and deadly genetic disease CD3 delta severe combined immunodeficiency.

21 Mar 2023

Clinical Trial News and Research

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Clinical trial of ENZAMET shows promising results for men with advanced prostate cancer

New evidence: Fibromyalgia could worsen opioid use disorder

Pulsed radiofrequency combined with steroid injection leads to better outcomes in patients with sciatica

New combination therapy shows promising results in some patients with advanced head and neck cancer

Chemotherapy plus immunotherapy improves outcomes in patients with advanced endometrial cancer

Surgeons can play an important role in reducing breast cancer disparities

Developers of gene therapies can utilize FDA guidance to prepare ODD or RPDD applications

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

SolasCure announces final closing of GBP 10.9m (c. USD 13.3m) Series B fundraise to advance wound care innovation

Intermittent fasting shows potential benefits for obesity treatment and brain-gut-microbiome health

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

Psychological therapy can help provide better quality of life for women with endometriosis

AI-based diagnostic screening system could streamline the diagnosis and treatment of gliomas

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

Fighting antibiotic-resistant "superbugs" with viruses

ACTG publishes study to simplify the administration of hepatitis C treatment

MHRA to introduce a series of new measures for streamlining clinical trial approvals

Avanced genome editing technology could be used as a one-time treatment for CD3 delta SCID

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