Genomic News and Research

RSS

Global blood centers join hands to develop more efficient, accurate blood typing technology

Blood centers from around the world have united to form an international collaboration with academic research institutions and a leading genomic array company, Thermo Fisher Scientific, to deliver a technology which promises to make the future of blood transfusion therapy more efficient, cost-effective, accurate, standardized, and safer.

17 Jun 2021

Researchers prepare for next coronavirus pandemic

Scientists are already preparing for a possible next coronavirus pandemic to strike, keeping with the seven-year pattern since 2004.

17 Jun 2021

UMSOM researchers receive $5 million federal grant to improve use of genetic risk scores

Researchers at the University of Maryland School of Medicine (UMSOM) have received a $5 million federal grant to pool genomic information from existing and new datasets - predominantly in African and African American populations -- in order to calculate the risk of developing specific diseases.

16 Jun 2021

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

UCLA Health will receive a $4.8 million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates - polygenic risk scores - for specific diseases in people from diverse populations and mixed ancestries.

16 Jun 2021

Scientists reveal the mechanism of liquid-liquid phase separation of SARS-CoV-2 nucleocapsid

A team of scientists from the United States has recently revealed how interactions between the SARS-CoV-2 nucleocapsid protein and the double-stranded RNA motifs impart distinct droplet properties that can support multiple viral functions. The study is currently available on the bioRxiv* preprint server.

16 Jun 2021

A study on SARS-CoV-2 proteins for the development of COVID-19 drugs

The authors of the review have grouped the virus proteins into three categories, (a) host-entry, (b) self-acting, and (c) host-interacting. Additionally, individual SARS-CoV-2 proteins are evaluated to be either directly targeted by drugs or block virus-host interactions.

16 Jun 2021

Analysis of COVID-19 patients with repeatedly positive SARS-CoV-2 tests

New research published on the medRxiv preprint server provides a detailed analysis of COVID-19 patients who had repeated positive PCR tests for SARS-CoV-2 infection in a large US COVID-19 electronic health record (EHR) database.

15 Jun 2021

Researchers develop new imaging technique for studying nanoscale coronavirus-host interactions

Lei S. Qi of Stanford University, California, and colleagues published research showing a potential framework to better characterize coronaviruses' biology. While most high-resolution imaging techniques show the life cycle of coronaviruses, identifying viral or host proteins and genomes remains poorly understood. Their results use multi-color super-resolution imaging allows them to study nanoscopic parts of the coronavirus, including RNA.

14 Jun 2021

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.

14 Jun 2021

Intranasal monoclonal SARS-CoV-2 antibody therapy shows promise in preclinical trials

A new study, released as a preprint on the bioRxiv* server, presents a new monoclonal antibody (MAb) called DZIF-10c that powerfully neutralizes SARS-CoV-2, including the current variants of concern (VOCs). With high bioavailability in the lungs and wide distribution in the body, the antibody was able to prevent SARS-CoV-2 infection in mice after intranasal administration.

14 Jun 2021

UCSF launches new initiative to propel the development of living therapeutics

UC San Francisco is launching a new initiative to propel the development of living therapeutics - a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease - and bring them quickly to patients.

14 Jun 2021

Delays and shortages hit SARS-CoV-2 genomic surveillance program

A new study from the Institute of Bioinformatics and Applied Biotechnology (IBAB), Bengaluru, India, provides an overview of how well this important monitoring mechanism is functioning around the world. The team has released their findings as a preprint on the bioRxiv* server.

14 Jun 2021

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

A recent study by researchers in Canada shows how mutations in newly emerging lineages of SARS-CoV-2 may disrupt the sequencing process and thus interfere with this important area of research.

14 Jun 2021

Novel computer system can help inform future therapies for patients with inherited heart disease

An integrated, genomic computer system for precision cardiology has been created using clinical data that can help inform medical and surgical decisions to support future therapies for patients with inherited heart disease.

14 Jun 2021

Long-range airborne transmission of SARS-CoV-2

In an early release copy of a short commentary paper recently published in the Canadian Medical Association Journal by Addleman et al. (June 8th, 2021), the impact of, and possible solutions to, the short- and long-range airborne transmission of SARS-CoV-2 are explored.

13 Jun 2021

Study identifies mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia

A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia.

11 Jun 2021

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Researchers remain perplexed as to what causes dementia and how to treat and reverse the cognitive decline seen in patients.

11 Jun 2021

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

AP-HP Greater Paris University Hospitals, the leading European clinical trial center with the largest amount of healthcare data in France dedicated to research and Owkin, a startup pioneering Federated Learning and AI technologies for medical research and clinical development, announced the recent results of their ongoing strategic collaboration at ASCO 2021.

10 Jun 2021

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

In order for cancer to grow and spread, it has to evade detection by our immune cells, particularly specialized "killer" T cells.

10 Jun 2021

Major anti-cancer protein released by neutrophils selectively kills tumor cells

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells.

10 Jun 2021

Genomic News and Research

Global blood centers join hands to develop more efficient, accurate blood typing technology

Researchers prepare for next coronavirus pandemic

UMSOM researchers receive $5 million federal grant to improve use of genetic risk scores

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

Scientists reveal the mechanism of liquid-liquid phase separation of SARS-CoV-2 nucleocapsid

A study on SARS-CoV-2 proteins for the development of COVID-19 drugs

Analysis of COVID-19 patients with repeatedly positive SARS-CoV-2 tests

Researchers develop new imaging technique for studying nanoscale coronavirus-host interactions

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Intranasal monoclonal SARS-CoV-2 antibody therapy shows promise in preclinical trials

UCSF launches new initiative to propel the development of living therapeutics

Delays and shortages hit SARS-CoV-2 genomic surveillance program

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

Novel computer system can help inform future therapies for patients with inherited heart disease

Long-range airborne transmission of SARS-CoV-2

Study identifies mechanisms by which COVID-19 can lead to Alzheimer's disease-like dementia

Study: cis P-tau is an early marker of vascular dementia, Alzheimer's disease

Identifying genomic subtypes of pancreatic cancer from histology slides using AI-based tool

Discovery suggests new pathways for safeguarding the immune system’s ability to fight cancer

Major anti-cancer protein released by neutrophils selectively kills tumor cells

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News