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Consuming sesame-based ingredients may reduce oxidative stress

The antioxidant boosting properties of sesame, and especially sesame oil, can have a significant effect on oxidative stress, improving human health, according to a systematic review published in Journal of Medicinal Food, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

18 May 2016

Sleeve gastrectomy can give optimal outcomes even in sweet eaters

Sleeve gastrectomy is a novel bariatric surgical procedure showing promising weight loss results, even among individuals classified as moderate or severe sweet eaters before the surgery.

15 May 2016

Researchers develop novel ss-siRNAs to turn off disease-related genes

Combining the therapeutic potential and advantages of existing oligonucleotide-based approaches to turn off disease-related genes, a type of single-stranded silencing RNAs (ss-siRNAs) has shown significantly improved potency and activity.

13 May 2016

Researchers investigate effects of non-allergenic components of pollen on allergy sufferers

Up to now, research into pollen allergies has largely focused on allergens - those components of pollen that trigger hypersensitivity reactions. When it comes into contact with the nasal mucous membrane, however, pollen releases a host of other substances in addition to allergens.

13 May 2016

Researchers develop bio-glass material that mimics real cartilage

Scientists have developed a material that can mimic cartilage and potentially encourage it to re-grow.

12 May 2016

High-throughput screening can help detect multiple compounds with potent antimicrobial activity

A new study in which researchers rapidly screened more than 11,000 bioactive molecules for activity against an antibiotic-resistant strain of Klebsiella pneumoniae bacteria identified multiple compounds with potent antimicrobial activity.

12 May 2016

Thermo Fisher Scientific reinforces ongoing commitment to make advanced technologies more accessible to customers

Thermo Fisher Scientific Inc., the world leader in serving science, today reinforced its ongoing commitment to help its customers accelerate innovation and enhance productivity.

12 May 2016

New study explores impact of infant feeding practices on childhood obesity risk

Does the timing of introducing solid foods to the infant diet affect a child's risk of being obese by 6 years of age? A new study from the Centers for Disease Control and Prevention (CDC) analyzed data on infant feeding practices, with a 6-year follow-up to determine obesity, and also explored the potential impact of breast versus formula feeding.

12 May 2016

Brazilian strain of Zika virus can cause severe birth defects

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first "direct experimental proof" that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

12 May 2016

New mouse model reveals underlying brain changes linked to autism's social, learning problems

A new mouse model of a genetically-linked type of autism reveals more about the role of genes in the disorder and the underlying brain changes associated with autism's social and learning problems.

11 May 2016

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Scientists in Manchester, who have developed a stem cell gene therapy to reverse a fatal childhood illness, have agreed to work with a new therapeutics company to test it in a human trial.

11 May 2016

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Two patients with melanoma that had spread to the liver survived for at least 8.5 and 12 years after resection of the hepatic tumor and treatment with patient-specific immunotherapeutic vaccines.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Study highlights role of specific chromosomal deletion in cancer development, progression

In a typical cancer cell, up to one-quarter of the genome is lost due to large chromosomal deletions, while the concomitant loss of hundreds of genes creates vulnerabilities that are impossible to reveal through the study of individual genes. Prof. Anna Sablina and her team at VIB/KU Leuven optimized a workflow for the generation of cell lines with targeted chromosomal deletions.

10 May 2016

Researchers find way to selectively deliver drugs to placenta without harming fetus

Nearly 10 percent of babies born in the United States are born premature, according to the March of Dimes. The underlying cause of many complications during pregnancy is often a poorly functioning placenta, the organ that nourishes and maintains the fetus.

9 May 2016

Unique attributes of zebrafish may help study human blood disorders

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable model organism to study normal hematopoetic development in humans as well as blood disorders and malignancies, as described in a Review article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 May 2016

Unlocking cellular trap door may help in finding cures for many diseases

A team of researchers who two years ago announced a "Trojan horse" method of entering a cell without harming it have now found, in effect, the lock to the cellular "trap door."

6 May 2016

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Promising results from the first clinical trials of globin gene transfer to treat beta-thalassemias-inherited forms of anemia-have eliminated the need for blood transfusions in some individuals.

6 May 2016

Use of cosmetics during pregnancy can have adverse effects on newborn’s health

A study led by SUNY Downstate Medical Center's School of Public Health presents evidence linking personal care products used during pregnancy to adverse reproductive effects in newborns.

5 May 2016

Simple 20-second upper arm extension test can identify frailty in older adults

A simple arm test that employs a novel wearable technology can rapidly and accurately identify physiological frailty in older adults, according to study results published online in the Journal of the American College of Surgeons in advance of print publication.

5 May 2016

Biotechnology News and Research

Consuming sesame-based ingredients may reduce oxidative stress

Sleeve gastrectomy can give optimal outcomes even in sweet eaters

Researchers develop novel ss-siRNAs to turn off disease-related genes

Researchers investigate effects of non-allergenic components of pollen on allergy sufferers

Researchers develop bio-glass material that mimics real cartilage

High-throughput screening can help detect multiple compounds with potent antimicrobial activity

Thermo Fisher Scientific reinforces ongoing commitment to make advanced technologies more accessible to customers

New study explores impact of infant feeding practices on childhood obesity risk

Brazilian strain of Zika virus can cause severe birth defects

New mouse model reveals underlying brain changes linked to autism's social, learning problems

Researchers agree to test new stem cell gene therapy for Sanfilippo disease in human trial

Patient-specific immunotherapeutic vaccines may improve overall survival of melanoma patients

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Study highlights role of specific chromosomal deletion in cancer development, progression

Researchers find way to selectively deliver drugs to placenta without harming fetus

Unique attributes of zebrafish may help study human blood disorders

Unlocking cellular trap door may help in finding cures for many diseases

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Use of cosmetics during pregnancy can have adverse effects on newborn’s health

Simple 20-second upper arm extension test can identify frailty in older adults

Event guide: 3rd IMPACCT Real World Evidence Summit Europe eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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