DNA News and Research

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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Ciliopathies: A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals.

25 Aug 2023

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

A new study published in Nature Communications demonstrates how small molecule inhibitors can be used to improve the precision and efficiency of CRISPR-Cas9 gene editing.

25 Aug 2023

Funding from Breast Cancer Now supports research into new drugs for secondary breast cancer in the bone

Researchers are testing new combinations of drugs to treat breast cancer that’s spread to the bone, thanks to funding from Breast Cancer Now.

25 Aug 2023

Researchers develop new, modular strategy for T-cell-based immunotherapy

Immunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively.

25 Aug 2023

Scientists create new test to identify people at risk of developing myeloid leukemias

Scientists have created a new test for identifying people at risk of developing acute myeloid leukaemia and related cancers, years before they do.

24 Aug 2023

Age-related changes in the blood system can exacerbate colon cancer

Researchers at the University of Florida College of Medicine have discovered how common age-related changes in the blood system can make certain colon cancers grow faster.

24 Aug 2023

Researchers find link between topography of the genome and presence of cancer mutations

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer.

24 Aug 2023

Largest genetic study of heart failure finds new risk factors

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

24 Aug 2023

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

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24 Aug 2023

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

23 Aug 2023

New gene variant linked to Parkinson's disease found in people of African ancestry

A gene variant found almost exclusively in the genomes of people of African ancestry increases the risk of developing Parkinson's disease, according to an international study of nearly 198,000 participants with this genetic background.

23 Aug 2023

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown.

23 Aug 2023

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

With around 90% of drugs failing to make it to market, the potential for improving efficiency within the drug development industry is clear. Drugs designed to combat cancers suffer similar rates of failure for many reasons.

23 Aug 2023

Long-read sequencing reveals new details of Bartter syndrome type 3

Bartter syndrome type 3 is the result of several structural variants in the genome. By using long-read sequencing, Janine Altmüller and her team from the Max Delbrück Center, the BIH and University Hospital Cologne mapped out the rare disease in unprecedented detail.

23 Aug 2023

Taking adult education classes may help prevent dementia

How can we best keep our brain fit as we grow older? It's well known that regular cognitive activity, for example brainteasers, sudokus, or certain video games in middle and old age tends to protect against cognitive decline and dementias like Alzheimer's.

23 Aug 2023

Y chromosome fully mapped for the first time

What was once the final frontier of the human genome - the Y chromosome - has just been mapped out in its entirety.

23 Aug 2023

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep, leading to breathing cessation lasting more than ten seconds and sometimes even several minutes, followed by arousals and deep breathing.

23 Aug 2023

DNA News and Research

Further Reading

Ciliopathies: A new understanding of the role of the NSL complex

Two small molecule inhibitors can help improve precision, efficiency of CRISPR-Cas9 gene editing

Funding from Breast Cancer Now supports research into new drugs for secondary breast cancer in the bone

Researchers develop new, modular strategy for T-cell-based immunotherapy

Scientists create new test to identify people at risk of developing myeloid leukemias

Age-related changes in the blood system can exacerbate colon cancer

Researchers find link between topography of the genome and presence of cancer mutations

Largest genetic study of heart failure finds new risk factors

Disruption of FOXA2 expression in congenital hyperinsulinism: The role of chromosome 20p11.2 deletions

Study shows how cancer can selfishly hijack a helpful immune pathway to spread

New gene variant linked to Parkinson's disease found in people of African ancestry

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

Stowers researchers reveal why certain anti-cancer drugs can cause unexpected side effects

Long-read sequencing reveals new details of Bartter syndrome type 3

Taking adult education classes may help prevent dementia

Y chromosome fully mapped for the first time

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Artificial intelligence and polyclonal antibody sequencing redefine the future of antibody discovery

The value of whole-exome sequencing as a first-tier genetic test in the diagnosis of skin disorders

The gut microbiota associated with prediabetes and treatment naïve type 2 diabetes patients

Understanding the DNA Damage Response in Innate Immunity eBook

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Evaluating new approaches for rare disease genomics

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