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Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Scientists discuss the characteristics, diagnostic evaluations, and cardiac diagnoses in patients referred to a clinic designed for patients with PASC.

9 Dec 2021

Effect of SARS-CoV-2 variant emergence on efficacy of neutralizing antibodies and vaccines

A review article focuses on the efficacy of neutralizing antibodies and vaccines against the SARS-CoV-2 variants.

9 Dec 2021

Glycans strengthen and lengthen SARS-Cov-2 spike binding to ACE2

New study results provide evidence that the binding between SARS-CoV-2 RBD and host ACE2 receptor is aided by the glycosylation on each protein.

9 Dec 2021

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Researchers have developed Nanocovax, a COVID-19 subunit vaccine based on recombinant protein technology to produce the extracellular (soluble) portion of the S protein of SARS-CoV-2.

9 Dec 2021

SARS-CoV-2 variants are evolving new ways to evade antibodies and vaccines

Continued replication of severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) under selective pressure from natural and vaccine-induced immunity has led to the emergence of variants of concern (VOCs) with increased transmissibility or virulence.

8 Dec 2021

Study shows SARS-CoV-2 transmission in Ireland before first official COVID-19 report

New study findings showed evidence of SARS-CoV-2 dissemination in Ireland prior to the identification of the first official COVID-19 case.

8 Dec 2021

Keto diet does not appear to work well for women

Scientists from UC Riverside are studying how the popular keto and intermittent fasting diets work on a molecular level, and whether both sexes benefit from them equally.

8 Dec 2021

CRISPR/Cas9 gene editing enables sonodynamic therapy to effectively shrink tumors

Sonodynamic therapy uses ultrasound in combination with drugs to release harmful reactive oxygen species (ROS) at the site of a tumor.

8 Dec 2021

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

A team of researchers set out to build a full-length, membrane-embedded spike to study its conformational dynamics at the atomic level using molecular dynamics simulations to understand better how this important component of the virus machinery works.

8 Dec 2021

Quantum mechanical characterization of SARS-CoV-2 Omicron variant interaction with human ACE2 receptor

Researchers from Universite Grenoble Alpes have been investigating the changes in the Omicron variant RBD and how they affect ACE2 binding.

8 Dec 2021

Computational comparison of SARS-CoV-2 Delta and Omicron variant binding affinity with ACE2

Researchers from the Management and Science University in Malaysia have used computational tools to investigate the new variant.

8 Dec 2021

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

A new study has focussed on determining the levels of nAb in individuals who received the second and third doses of the RNA vaccines developed by Pfizer and Moderna.

8 Dec 2021

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Researchers investigate the conformational dynamics of the SARS-CoV-2 RBD using the atomistic molecular dynamics simulation method.

7 Dec 2021

Homologous mRNA and heterologous vaccines elicit high immune responses

New study findings show that homologous mRNA or heterologous vaccination induces the highest immune responses due to high RBD- and S1-specific antibodies.

7 Dec 2021

Possible impact of spike protein mutations on SARS-CoV-2 Omicron variant

The current study not only analyses the mutations in the Omicron spike variant but classifies various combinations of spike mutations into groups.

7 Dec 2021

Impact of post-translational modifications in the pathogenicity of SARS-CoV-2

A new study provides understanding of the intricate roles and functions of the different elements of spike proteins and shows how the spike protein samples a crowded surface of its host cell via the glycans.

7 Dec 2021

Study suggests algal polysaccharide may be a promising anti-COVID-19 candidate

Researchers from the Rensselaer Polytechnic Institute have been investigating the potential of rhamnan sulfate as an antiviral agent.

7 Dec 2021

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Researchers develop a virus-like particle for SARS-CoV-2 based on the co-expression of the spike, membrane, and envelope structural proteins.

6 Dec 2021

Researchers use gene-editing to create single sex mice litters

Scientists at the Francis Crick Institute, in collaboration with University of Kent, have used gene editing technology to create female-only and male-only mice litters with 100% efficiency.

6 Dec 2021

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

This work has emphasized the clinical and translational potential of paper-based biosensors.

6 Dec 2021

Enzyme News and Research

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Effect of SARS-CoV-2 variant emergence on efficacy of neutralizing antibodies and vaccines

Glycans strengthen and lengthen SARS-Cov-2 spike binding to ACE2

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

SARS-CoV-2 variants are evolving new ways to evade antibodies and vaccines

Study shows SARS-CoV-2 transmission in Ireland before first official COVID-19 report

Keto diet does not appear to work well for women

CRISPR/Cas9 gene editing enables sonodynamic therapy to effectively shrink tumors

Equilibrium simulation of SARS-CoV-2 spike protein highlights its global conformational characteristics

Quantum mechanical characterization of SARS-CoV-2 Omicron variant interaction with human ACE2 receptor

Computational comparison of SARS-CoV-2 Delta and Omicron variant binding affinity with ACE2

Does a COVID-19 vaccine booster improve the immune response of a poor responder?

SARS-CoV-2 Delta variant changes receptor binding domain conformation to escape host antibodies

Homologous mRNA and heterologous vaccines elicit high immune responses

Possible impact of spike protein mutations on SARS-CoV-2 Omicron variant

Impact of post-translational modifications in the pathogenicity of SARS-CoV-2

Study suggests algal polysaccharide may be a promising anti-COVID-19 candidate

SARS-CoV-2 virus-like particles elicit potent neutralizing antibody response in variant challenge

Researchers use gene-editing to create single sex mice litters

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

Measuring Drug-Target Residence Times with Biochemical Assays eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo