Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

PK molecule could be a target for vascular complications linked to type 1 diabetes

In an article published ahead of print on November 24, 2015 in the journal Diabetes (available at http://dx.doi.org/10.2337/db15-0930), researchers from the Medical University of South Carolina, the American University of Beirut, and Case Western Reserve University report that a molecule called pre-kallikrein (PK) could be a target for the vascular complications associated with type 1 diabetes.

18 Jan 2016

UM SOM to team up with industry to develop vaccine for preventing deadly bacterial infections

The Center for Vaccine Development at the University of Maryland School of Medicine will participate in a partnership with industry to develop a vaccine to prevent a group of deadly bacterial infections that occur commonly among hospital patients.

13 Jan 2016

Using statins before and after heart surgery can help reduce cardiac complications, mortality risks

Using statins before and after coronary artery bypass grafting (CABG) surgery can help reduce cardiac complications, such as atrial fibrillation, following surgery and also can reduce the risk of death during and after surgery, according to a review article posted online today by The Annals of Thoracic Surgery.

13 Jan 2016

Racial disparity in 'previable' preterm births linked to infant mortality problem

Black women are nearly four times more likely than white women to have a baby born between 16 and 22 weeks gestation, a time period in which the life of a baby outside the womb is not viable.

13 Jan 2016

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

Researchers have identified a molecular target and experimental treatment strategy for DNA repair defects behind Fanconi anemia – a complex genetic disorder responsible for birth anomalies, organ damage, anemia and cancer.

12 Jan 2016

SIMnext introduces DR Doppler Dynamic Ultrasonography Training System

Health care professionals now have a new way of accessing ultrasound training in a mobile and affordable manner using the DR Doppler Dynamic Ultrasonography Training System (DR Doppler), a training tool from SIMnext, LLC, a medical simulation research and development company based in Peoria, Ill.

12 Jan 2016

JINARC (tolvaptan) accepted for use in Scotland for ADPKD treatment

From today, people in Scotland with the genetic kidney disease ADPKD could benefit from JINARC® (tolvaptan) following advice issued by the Scottish Medicines Consortium (SMC) for its use in adults with chronic kidney disease (CKD) stages 1-3 at the start of treatment with evidence of rapidly progressing disease.

12 Jan 2016

DNA-binding protein acts like genetic traffic signal to orchestrate early stage embryonic development

New research by UC San Francisco stem cell biologists has revealed that a DNA-binding protein called Foxd3 acts like a genetic traffic signal, holding that ball of undifferentiated cells in a state of readiness for its great transformation in the third week of development.

11 Jan 2016

CTCA at Western announces launch of Phase II NivoPlus clinical trial

Cancer Treatment Centers of America at Western Regional Medical Center in Goodyear, Arizona, has announced the launch of Phase II of the NivoPlus clinical trial, which combines the immunotherapeutic agent nivolumab with chemotherapy drugs irinotecan and capecitabine.

11 Jan 2016

Cancer mortality continues to drop in the U.S.

Steady reductions in smoking combined with advances in cancer prevention, early detection, and treatment have resulted in a 23% drop in the cancer death rate since its peak in 1991. The drop translates to more than 1.7 million cancer deaths averted through 2012.

8 Jan 2016

Study shows that twins may share cancer risk

In a long-term follow-up study among approximately 200,000 Nordic twin individuals, there was an increased cancer risk in twins whose co-twin was diagnosed with cancer, with an increased risk for cancer overall and for specific types of cancer, including prostate, melanoma, breast, ovary, and uterus, according to a study in the January 5 issue of JAMA.

7 Jan 2016

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

DURECT Corporation today announced the successful completion of a Phase 1 clinical trial with an injectable formulation of DUR-928 intended for acute use indications. DUR-928 is an endogenous, small-molecule, new chemical entity (NCE), which may have broad applicability in metabolic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH), and in acute organ injuries such as acute kidney injury (AKI).

6 Jan 2016

Buprenorphine superior to methadone in reducing duration of treatment for babies born in drug withdrawal

A study of two opioids used to wean babies born in withdrawal from drugs their mothers have taken shows that buprenorphine is superior to methadone in reducing duration of treatment and length of hospital stay.

6 Jan 2016

New study finds familial risk and heritability of cancer among twins

A large new study of twins has found that having a twin sibling diagnosed with cancer poses an excess risk for the other twin to develop any form of cancer. Among the 23 different types of cancer studied, an excess familial risk was seen for almost all of the cancers, including common cancers such as breast and prostate cancer, but also more rare cancers such as testicular cancer, head and neck cancer, melanoma, ovarian and stomach cancer.

6 Jan 2016

New allocation system boosts kidney transplantation rates for black and Hispanic patients on waiting lists

Year-old changes to the system that distributes deceased donor kidneys nationwide have significantly boosted transplantation rates for black and Hispanic patients on waiting lists, reducing racial disparities inherent in the previous allocation formula used for decades, according to results of research led by a Johns Hopkins transplant surgeon.

6 Jan 2016

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

Ardelyx, Inc., a clinical-stage biopharmaceutical company focused on gastrointestinal and cardio-renal diseases, today announced positive results of an open label clinical study evaluating the pharmacodynamic (PD) activity of RDX022 in healthy adult volunteers.

5 Jan 2016

UVA-developed artificial pancreas system to undergo final testing in two clinical trials

A device developed by University of Virginia School of Medicine researchers to automatically monitor and regulate blood-sugar levels in people with type 1 diabetes will undergo final testing in two clinical trials beginning in early 2016.

5 Jan 2016

Continental Who's Who recognizes Dr. Veryl D. Hodges as a Pinnacle Professional in the healthcare field

Dr. Veryl D. Hodges, D.O., F.A.C.O.I., is recognized by Continental Who's Who among Pinnacle Professionals in the field of Healthcare as a result of his role as Doctor of Osteopathic Medicine at Clopton Clinic.

31 Dec 2015

HealthWell Foundation opens new fund to provide financial assistance to Medicare patients suffering from RCC

The HealthWell Foundation, an independent non-profit that provides a financial lifeline for inadequately insured Americans, today announced it has opened a new fund to provide financial assistance to Medicare patients suffering from renal cell carcinoma (RCC).

31 Dec 2015

MUSC researchers awarded NIH grant to study use of technology for kidney transplant patients

A group of MUSC researchers in the College of Medicine's Department of Surgery and the College of Nursing has been awarded a $1.11 million National Institutes of Health grant to examine a novel use of mobile health technology to reduce kidney transplant recipient premature graft loss.

30 Dec 2015

Nephrology News and Research

Further Reading

PK molecule could be a target for vascular complications linked to type 1 diabetes

UM SOM to team up with industry to develop vaccine for preventing deadly bacterial infections

Using statins before and after heart surgery can help reduce cardiac complications, mortality risks

Racial disparity in 'previable' preterm births linked to infant mortality problem

Researchers discover molecular target for DNA repair defects behind Fanconi anemia

SIMnext introduces DR Doppler Dynamic Ultrasonography Training System

JINARC (tolvaptan) accepted for use in Scotland for ADPKD treatment

DNA-binding protein acts like genetic traffic signal to orchestrate early stage embryonic development

CTCA at Western announces launch of Phase II NivoPlus clinical trial

Cancer mortality continues to drop in the U.S.

Study shows that twins may share cancer risk

DURECT reports successful completion of DUR-928 Phase 1 study for acute use indications

Buprenorphine superior to methadone in reducing duration of treatment for babies born in drug withdrawal

New study finds familial risk and heritability of cancer among twins

New allocation system boosts kidney transplantation rates for black and Hispanic patients on waiting lists

Ardelyx announces positive results from RDX022 clinical study for treatment of hyperkalemia

UVA-developed artificial pancreas system to undergo final testing in two clinical trials

Continental Who's Who recognizes Dr. Veryl D. Hodges as a Pinnacle Professional in the healthcare field

HealthWell Foundation opens new fund to provide financial assistance to Medicare patients suffering from RCC

MUSC researchers awarded NIH grant to study use of technology for kidney transplant patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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