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Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

New insights into migraine etiology: the role of hepatocyte growth factor

The causal links between pro-inflammatory cytokine expression and migraine.

10 Nov 2023

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

A new paper recently published in Nature, reported the examination of synovial tissue from the joints of nearly 80 people with RA, in combination with RNA sequencing and surface protein analyses.

10 Nov 2023

Beckman Coulter Life Sciences and Pillar Biosciences announce NGS application development pipeline for the Biomek NGeniuS System

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, continues to lead the way with next-generation sequencing (NGS) research solutions. Today the company announces a collaboration agreement with Pillar Biosciences, which develops and distributes IVD & RUO NGS testing solutions based on their proprietary SLIMamp® technology to help localize patient testing and optimize the selection of precision therapies for cancer patients.

From Beckman Coulter Life Sciences 10 Nov 2023

SDF-4 protein shows promise for early detection of gastric cancer

A research team led by the Nagoya University Graduate School of Medicine has discovered that the stromal cell-derived factor 4 (SDF-4) protein is a reliable cancer marker.

9 Nov 2023

HMS immunologist unravels the mysteries of how the immune system communicates

The immune system is a crucial part of our survival, regularly fending off wide-ranging attacks on the body, both internal and external.

9 Nov 2023

Tumor-immune interactions predict treatment responses in multiple myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

9 Nov 2023

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

The role of interleukin (IL)-6 and IL-1α in sterile intraamniotic inflammation (SIAI), a condition associated with preterm birth (PTB).

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Miami Dolphins and AutoNation team up to address breast cancer disparities

The Miami Dolphins and AutoNation have teamed up to fund a $1-million, four-year Breast Cancer Research Foundation (BCRF) project at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

8 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

Genetic information collected from seemingly healthy tissue near lung tumors may be a better predictor of whether cancer will come back after treatment than analysis of the tumors themselves, according to new research led by NYU Langone Health and its Perlmutter Cancer Center.

8 Nov 2023

New drug shows exciting promise for the treatment of ALS

In science, a simple but thorough observation can kick-start the most surprising findings. Researchers at the Hollings Cancer Center at the Medical University of South Carolina noticed that mice lacking a protein of interest in cancer research were showing visible signs of abnormal motor functions as they aged, including loss of coordination and strength.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

AI-powered radiation therapy revolutionizes cancer treatment at Henry Ford West Bloomfield Hospital

Patients undergoing radiation therapy for certain types of cancer at Henry Ford West Bloomfield Hospital are among the first in the country with access to a cutting-edge treatment system that increases accuracy and precision, enhances patient comfort, and minimizes side effects.

8 Nov 2023

Tumor News and Research

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Preclinical research points to a promising new treatment option for pancreatic cancer patients

New insights into migraine etiology: the role of hepatocyte growth factor

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

Beckman Coulter Life Sciences and Pillar Biosciences announce NGS application development pipeline for the Biomek NGeniuS System

SDF-4 protein shows promise for early detection of gastric cancer

HMS immunologist unravels the mysteries of how the immune system communicates

Tumor-immune interactions predict treatment responses in multiple myeloma

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Miami Dolphins and AutoNation team up to address breast cancer disparities

Gamma delta T cells engineered to be more potent and long-lasting against cancer

Gene expression in nearby healthy tissue may be a better predictor of lung cancer recurrence

New drug shows exciting promise for the treatment of ALS

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

AI-powered radiation therapy revolutionizes cancer treatment at Henry Ford West Bloomfield Hospital

Study shows linear associations between body mass index and site-specific tumors in young males

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

How glucose restriction makes lung cancer cells more aggressive

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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