immunity News and Research

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Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

Researchers identified an ultralong bovine antibody that neutralizes SARS-CoV-2 and SARS-CoV.

11 Apr 2022

The effect of unsuppressed HIV on T-cell response to COVID-19

A new study evaluates the impact of HIV infection on SARS-CoV-2 T-cell responses during the first and second waves of COVID-19 in South Africa.

10 Apr 2022

CDC report on Omicron infections soon after Delta

A new study identifies ten patients with confirmed SARS-CoV-2 Omicron variant infections within 90 days of a previous Delta variant infection.

10 Apr 2022

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Published in Nature Communications, research from the University of Minnesota and Mayo Clinic sought to understand how microbial communities help people resist pathogens.

8 Apr 2022

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Intestinal epithelial cells line the inner wall of the gut, creating a barrier to dangerous bacteria like enteropathogenic E. coli that seek to attach and efface that barrier, causing diarrhea.

8 Apr 2022

Study explores the antibody evasion pattern of SARS-CoV-2 Omicron sublineages

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8 Apr 2022

SARS-CoV-2 Omicron variant spike-specific unique cluster of differentiation cells

A new study presented a safe and efficient multi-epitope SARS-CoV-2 vaccine construct against SARS-CoV-2 variants, including Omicron.

8 Apr 2022

Evaluating immunogenicity after BNT162b2 booster vaccination

Researchers assessed the levels of IgG and IgA antibodies in sera samples from healthcare workers before vaccination, after the first vaccine dose, after eight months, and after a booster shot.

8 Apr 2022

SARS-CoV-2 Delta-Omicron recombinant identified in a transplant patient treated with Sotrovimab

Researchers described a case of co-infection with SARS-CoV-2 variants of concern, Delta and Omicron.

8 Apr 2022

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

In a new study, researchers characterized over 100 SARS-CoV-2-specific CD4+ T-cell epitopes.

8 Apr 2022

Role of natural immunity to SARS-CoV-2 on post-vaccination antibody responses in staff and residents of long-term care facilities

A new study collected and analyzed sera from the staff at a local long-term care facility from August to December 2020, where an outbreak occurred in September 2020.

8 Apr 2022

Neutralization potency against the Omicron variant of naturally expressed MBC-derived IgG antibodies from vaccinated individuals

Researchers have shown how the Omicron variant of the SARS-CoV-2 successfully evaded a large fraction of antibodies derived from memory B cells, giving rise to a reduced, but incomplete immune escape.

8 Apr 2022

SARS-CoV-2 mutations capable of widespread T-cell escape

A new study aimed to identify and screen the mutations observed in SARS-CoV-2 that help to facilitate CD8+ T-cell escape.

7 Apr 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

A recent study analyzed the antibody that mediated the COVID-19 vaccine-induced thrombotic thrombocytopenia.

7 Apr 2022

Study investigates changing patterns of SARS-CoV-2 infection through Delta and Omicron waves

A new study examined whether SARS-CoV-2 infections in England varied by vaccination status, in cases with a previous COVID-19 positive test report individual, and by neighborhood socioeconomic deprivation, across the Delta and Omicron waves.

7 Apr 2022

Study finds vaccines effectively reduce deaths from COVID-19 but not the prevalence of infections

Researchers in Australia have investigated COVID-19 vaccine effectiveness on the prevalence and mortality of the Delta variant.

7 Apr 2022

Transcriptional reprogramming of monocytes in COVID-19

In a recent study posted to the bioRxiv* server, researchers examined the functionality of cluster of differentiation 14-positive (CD14+) monocytes in patients with mild or moderate coronavirus disease 2019 (COVID-19).

7 Apr 2022

SARS-CoV-2 spike S375F mutation triggered the explosive spread of Omicron

In a recent study posted to the bioRxiv* preprint server, researchers investigated the mutation in the viral spike (S) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.1 variant (referred to as Omicron in the present study) that is responsible for the variant’s virological features.

7 Apr 2022

SARS-CoV-2 transmission in first few X cases and households

In a study posted to the medRxiv* preprint server, researchers conducted a systematic review and meta-analysis to determine the household secondary infection attack rate (hSAR) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

6 Apr 2022

immunity News and Research

Ultralong bovine antibody targets cryptic and conserved epitope on SARS-CoV and SARS-CoV-2

The effect of unsuppressed HIV on T-cell response to COVID-19

CDC report on Omicron infections soon after Delta

Researchers seek to understand how microbes in the GI tract help people resist pathogens

Study defines nonredundant role for T cell-derived interleukin-22 in antibacterial defense of colonic crypts

Study explores the antibody evasion pattern of SARS-CoV-2 Omicron sublineages

SARS-CoV-2 Omicron variant spike-specific unique cluster of differentiation cells

Evaluating immunogenicity after BNT162b2 booster vaccination

SARS-CoV-2 Delta-Omicron recombinant identified in a transplant patient treated with Sotrovimab

Study characterizes SARS-CoV-2 spike-specific cluster of differentiation 4+ T-cell response

Role of natural immunity to SARS-CoV-2 on post-vaccination antibody responses in staff and residents of long-term care facilities

Neutralization potency against the Omicron variant of naturally expressed MBC-derived IgG antibodies from vaccinated individuals

SARS-CoV-2 mutations capable of widespread T-cell escape

Researchers design RNA molecules for delivering therapies directly to beta cells

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

Study investigates changing patterns of SARS-CoV-2 infection through Delta and Omicron waves

Study finds vaccines effectively reduce deaths from COVID-19 but not the prevalence of infections

Transcriptional reprogramming of monocytes in COVID-19

SARS-CoV-2 spike S375F mutation triggered the explosive spread of Omicron

SARS-CoV-2 transmission in first few X cases and households

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