Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Comparison of antibody responses and vaccine effectiveness in healthcare workers post-primary COVID-19 vaccination

The authors highlight that they have shown that boosted individuals are significantly more protected against SARS-CoV-2 infection than any other group

18 Jan 2022

Antibody responses to COVID-19 mRNA vaccines in a cohort of healthcare workers

Researchers have been investigating the vaccine response of healthcare workers from specific vaccines to different variants.

18 Jan 2022

Researchers report isolation of potently neutralizing antibodies against highly transmissible SARS-CoV-2 variants

A recent preprint discusses using a combinatorial phage-display library approach to COVIID-19 antibodies.

18 Jan 2022

Immune responses in Omicron breakthrough COVID-19

A recent study examined the question as to whether vaccination protects against Omicron infection by assessing breakthrough infection rates in participants at a superspreader event.

18 Jan 2022

An alternative mouse model of SARS-CoV-2 infection

Recently, a study has shown the possibility of repurposing hACE2 transgenic mice, primarily raised to study SARS-CoV, to support SARS-CoV-2 infection and pathogenesis.

17 Jan 2022

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Researchers prevent evidence on the efficacy of neutralizing monoclonal antibodies in treating COVID-19.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

In a new study, a team of researchers demonstrated that Japan had witnessed a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant-induced endemic between August and December 2021.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Nine-month survey of COVID-19 vaccine effectiveness in North Carolina

A new paper reports increased breakthrough infections with SARS-CoV-2, the agent behind the ongoing COVID-19 pandemic.

17 Jan 2022

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

A new paper published in the journal JCI Insight reports on the differential levels of immunity achieved in those with and without a history of prior infection with the virus following one and two doses of the earliest vaccines to be approved for emergency use.

17 Jan 2022

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

A new study led by researchers at Harvard Medical School has identified a set of cellular receptors for at least three related alphaviruses shared across mosquitoes, humans, and animals that host the virus.

17 Jan 2022

WHO's recommendation provides two new options for treating COVID-19

WHO has recommended two new drugs for COVID-19, providing yet more options for treating the disease. The extent to which these medicines will save lives depends on how widely available and affordable they will be.

16 Jan 2022

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

In a large prospective study of just over 1,000 patients ages 17 and younger who were seen at the Baltimore Convention Center Field Hospital (BCCFH) testing site during a seven-month period last year, researchers from Johns Hopkins Medicine and collaborating institutions report that a rapid antigen test for SARS-CoV-2 — the virus that causes COVID-19 — proved highly accurate when compared to the established standard virus detection method: the polymerase chain reaction (PCR).

16 Jan 2022

Antibody News and Research

Further Reading

Comparison of antibody responses and vaccine effectiveness in healthcare workers post-primary COVID-19 vaccination

Antibody responses to COVID-19 mRNA vaccines in a cohort of healthcare workers

Researchers report isolation of potently neutralizing antibodies against highly transmissible SARS-CoV-2 variants

Immune responses in Omicron breakthrough COVID-19

An alternative mouse model of SARS-CoV-2 infection

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Seroepidemiologic surveys for assessment of the COVID-19 pandemic in Japan

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Nine-month survey of COVID-19 vaccine effectiveness in North Carolina

Study investigates whether immune responses to BNT162b2 vaccine differ in subjects with and without prior SARS-CoV-2 infection

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

WHO's recommendation provides two new options for treating COVID-19

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

UV-C light prevents airborne transmission of SARS-CoV-2

SARS-CoV-2 Omicron has similar infectious viral load to Delta

Synthetic antibody demonstrates Omicron detection along with all other variants of concern

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

Using single B cell screening to boost antibody discovery eBook

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Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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