Protein C News and Research

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Machine learning identifies cancer-driving mutations at CTCF binding sites

Researchers developed a machine learning tool, CTCF-INSITE, to identify mutational hotspots at persistent CTCF binding sites across various cancers, highlighting their role in genomic structure disruption and cancer progression.

7 Jul 2024

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Researchers discovered that interferon-stimulated SAMD9L restricts HIV-1 and other lentiviruses by inhibiting viral translation and endosomal trafficking, while SAMD9 enhances HIV-1 replication.

7 Jul 2024

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

An international panel of experts led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the "la Caixa" Foundation, under the umbrella of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment, has produced a consensus statement on sex and gender disparities in resilience to Alzheimer's disease and call for incorporating these differences in future research.

5 Jul 2024

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumor-suppressing gene called VHL, the first step in a huge research endeavor to unpick the outcomes of tens of thousands of genetic variations in genes associated with cancer.

5 Jul 2024

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

The impact of heparan-sulfate-modified proteoglycans (HSPGs) on Alzheimer's disease-associated pathways.

5 Jul 2024

New signaling pathway identified in aural migraine headaches

The rapid influx of cerebral spinal fluid (CSF) and protein solutes released during cortical spreading depression (CSD) in the brain activates neurons to trigger aural migraine headaches, according to a new mouse study.

4 Jul 2024

Innovative aptamer cream shows promise in treating allergic contact dermatitis in mice

Researchers at the University of Bonn have isolated a DNA molecule that is suitable for combating allergic contact dermatitis in mice.

4 Jul 2024

More than 1,000 small changes in DNA identified that influence age of first period

Researchers examined nearly 800,000 women's DNA to explore puberty timing complexities. They identified signals related to menarche timing and investigated their influence on puberty onset.

4 Jul 2024

Study suggests gastric bypass can reduce cardiovascular disease risk, irrespective of weight loss

Researchers investigated whether Roux-en-Y gastric bypass reduces cardiovascular risk factors independent of calorie restriction and weight loss.

4 Jul 2024

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

Researchers found that KLF15 is crucial for maintaining white adipocyte properties in subcutaneous fat, and its deletion induces beige adipocyte characteristics, suggesting new obesity treatment pathways.

4 Jul 2024

New study reveals how RNA polymerase opens the transcription bubble in real time

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA.

3 Jul 2024

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

Progressive supranuclear palsy (PSP), a mysterious and deadly neurological disorder, usually goes undiagnosed until after a patient dies and an autopsy is performed.

3 Jul 2024

Study offers new insights into the evolution of foldable proteins

A new study led by Rice University's Peter Wolynes offers new insights into the evolution of foldable proteins. The research was published in the Proceedings of the National Academy of Sciences.

3 Jul 2024

Inflammation in early adulthood may be linked to memory and thinking problems at middle age

Having higher levels of inflammation in your 20s and 30s may be linked to having memory and thinking problems at middle age, according to a study published in the July 3, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

3 Jul 2024

Protein C News and Research

Machine learning identifies cancer-driving mutations at CTCF binding sites

Novel antiviral protein SAMD9L blocks HIV-1 and other lentiviruses

Experts produce consensus statement on sex and gender disparities in resilience to Alzheimer's

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Heparan-sulfate proteoglycans found to influence Alzheimer's cell pathology

New signaling pathway identified in aural migraine headaches

Innovative aptamer cream shows promise in treating allergic contact dermatitis in mice

More than 1,000 small changes in DNA identified that influence age of first period

Study suggests gastric bypass can reduce cardiovascular disease risk, irrespective of weight loss

Scientists unveil KLF15 transcription factor's role in white fat cells, opening new paths for obesity therapy

New study reveals how RNA polymerase opens the transcription bubble in real time

Protein biomarkers in spinal fluid offer promise for early progressive supranuclear palsy diagnosis

Study offers new insights into the evolution of foldable proteins

Inflammation in early adulthood may be linked to memory and thinking problems at middle age

Protein nanocages: A promising frontier in mRNA therapeutics

New AI tool can help select the most suitable treatment for cancer patients

White blood cell type identified as important contributor to inflammation in obesity

RNA splicing modulation as a precision approach for neuroendocrine cancer treatment

AI uncovers potential cancer drivers hidden in 'junk' regions of DNA

Study reveals new mechanisms behind severe COVID-19 in obese individuals without diabetes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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