Therapeutics News and Research

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Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

19 May 2022

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

18 May 2022

Developing innovative approaches to combat urinary tract infections

The German government is providing about 2.4 million Euros for a new research group in infectious diseases at JMU Würzburg.

18 May 2022

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Imugene Limited, a clinical stage immuno-oncology company, and City of Hope, one of the largest cancer research and treatment organizations in the United States, today announced that the first patient was dosed in a Phase 1 clinical trial evaluating the safety of novel cancer-killing virus CF33-hNIS VAXINIA when used in people with advanced solid tumors.

18 May 2022

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

A new study published in the journal Life Sciences has focused on examining the effects of ORF8 and ORF10 genes and SARS-CoV-2 Membrane (M) protein on apoptosis.

17 May 2022

Experimental drug more effective than existing FDA-approved medications for ALS

New research on the experimental drug, NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the disease.

17 May 2022

Exploring mutational energetics and the role of arginine blockers in COVID-19 treatments

A new study aimed to describe the roles of certain specific mutations in SARS-CoV-2 strains, with respect to their ability to conformationally stabilize S-protein structure resulting in enhanced receptor-binding domain ACE2 binding.

17 May 2022

Inflammation plays a key role in resolving pain

In a recent study published in the journal Science Translational Medicine, researchers explored the mechanisms underlying the transition from acute to chronic low back pain (LBP) by transcriptome-wide analysis of peripheral immune cells from acute LBP patients.

17 May 2022

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

In a recent study published in the journal Vaccines, researchers developed plant-based monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

17 May 2022

UK EMT gets Solomon Islands prepared for potential subsequent waves of COVID-19

This was made possible through the UK Government's deployment of its Emergency Medical Team (EMT) who were in the country over the last nine weeks.

16 May 2022

CDC study reveals hybrid SARS-CoV-2 spike from Delta/Omicron recombination event

The US Centers for Disease Control and Prevention (CDC) has conducted national-level genomic surveillance to identify and characterize delta-omicron recombinant genomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A total of nine genomes with a hybrid delta-omicron spike protein have been identified.

14 May 2022

A*STAR, NHCS, NUS, and Novo Nordisk partner to study the mechanisms underlying heart failure

The Agency for Science, Technology and Research's Genome Institute of Singapore and Bioinformatics Institute, as well as the National Heart Centre Singapore, National University of Singapore, and pharmaceutical company Novo Nordisk have signed an agreement to study the mechanisms underlying cardiovascular disease progression - especially the condition called heart failure with preserved ejection fraction (HFpEF).

13 May 2022

Should you worry about data from your period-tracking app being used against you?

It's estimated that millions of people in the U.S. use period-tracking apps to plan ahead, track when they are ovulating, and monitor other health effects. The apps can help signal when a period is late.

13 May 2022

New therapeutic approach for cardiac repair after a heart attack

Following a heart attack, the human body is incapable of repairing lost tissue due to the heart's inability to generate new muscle.

12 May 2022

Phase 1 trial of COVID-19 PTXCOVID19-B vaccine

A new study demonstrated that the SARS-CoV-2 PTXCOVID19-B vaccine was a promising SARS-CoV-2 vaccine option.

12 May 2022

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

In health care, perhaps no word sends a more chilling message than "cancer." Brain tumors, for example, prove especially resistant to current treatments. Only 5% of patients with that condition survive more than three years and the median survival time is 10 to 14 months.

12 May 2022

Researchers Identify Potential Target for Rhabdomyosarcoma Recurrence Prevention

In this interview, News-Medical speaks to Anand Patel and Michael Dyer from St. Jude's Children's Research Hospital about their recent research suggesting EGFR inhibitors may prevent rhabdomyosarcoma recurrence.

12 May 2022

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Rutgers study identifies key protein for brain stem cell longevity

A receptor that was first identified as necessary for insulin action, that also is located on the neural stem cells found deep in the brains of mice, is pivotal for brain stem cell longevity, according to a Rutgers study, a finding that has important implications for brain health and future therapies for brain disorders.

11 May 2022

Therapeutics News and Research

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

Developing innovative approaches to combat urinary tract infections

First patient dosed in Phase 1 clinical trial evaluating the safety of CF33-hNIS against solid tumors

Impact of cannabidiol on cellular innate immune responses to SARS-CoV-2 genes

Experimental drug more effective than existing FDA-approved medications for ALS

Exploring mutational energetics and the role of arginine blockers in COVID-19 treatments

Inflammation plays a key role in resolving pain

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

UK EMT gets Solomon Islands prepared for potential subsequent waves of COVID-19

CDC study reveals hybrid SARS-CoV-2 spike from Delta/Omicron recombination event

A*STAR, NHCS, NUS, and Novo Nordisk partner to study the mechanisms underlying heart failure

Should you worry about data from your period-tracking app being used against you?

New therapeutic approach for cardiac repair after a heart attack

Phase 1 trial of COVID-19 PTXCOVID19-B vaccine

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

Researchers Identify Potential Target for Rhabdomyosarcoma Recurrence Prevention

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

The promise of RNA medicine is targeted and personalized

Rutgers study identifies key protein for brain stem cell longevity

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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