Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Study: Blood test can predict response of advanced prostate cancer patients to treatments

An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.

25 Jul 2018

MODEL-AD Center releases eight new mouse models for Alzheimer's research

The MODEL-AD Center, an ambitious project to develop and distribute precise mouse models of late-onset Alzheimer's disease (AD), has released eight new models carrying genetic mutations found in patients.

23 Jul 2018

Scientists create wearable device that measures cortisol in sweat

The hormone cortisol rises and falls naturally throughout the day and can spike in response to stress, but current methods for measuring cortisol levels require waiting several days for results from a lab.

20 Jul 2018

ECU researchers develop world’s first blood test that detects melanoma in its early stages

Edith Cowan University researchers have developed the world’s first blood test capable of detecting melanoma in its early stages, a breakthrough that will save thousands of lives, as well as millions of dollars for the health system.

20 Jul 2018

Top AI companies join hands to discover novel drugs for DMD

Insilico Medicine a leader in artificial intelligence for drug discovery, biomarker development and aging research, announced a research collaboration agreement with A2A Pharmaceuticals, Inc. A2A is a biotechnology company headquartered in New York and focused on development of novel drugs for unmet needs in oncology, drug resistant bacterial infections, and other life threatening diseases.

20 Jul 2018

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Scientists at Dana-Farber/Brigham and Women's Cancer Center have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

19 Jul 2018

Mother's microbiome determines offspring's risk of developing autism

The risk of developing autism-spectrum disorders is determined by the mother's microbiome - the collection of microorganisms that naturally live inside us - during pregnancy, new research from the University of Virginia School of Medicine suggests.

18 Jul 2018

Conservative management of lung subsolid nodules reduces overtreatment and unnecessary surgery

Subsolid nodules can be considered a biomarker of lung cancer risk and should be managed with long-term active surveillance.

18 Jul 2018

Traumatic brain injury biomarker could help predict patient prognosis

A preclinical study has shown that levels of lysophosphatidic acid (LPA) are significantly increased following traumatic brain injury (TBI).

16 Jul 2018

Four-protein biomarker blood test improves lung cancer risk assessment for smokers

A four-protein biomarker blood test improves lung cancer risk assessment over existing guidelines that rely solely upon smoking history, capturing risk for people who have ever smoked, not only for heavy smokers, an international research team reports in JAMA Oncology.

12 Jul 2018

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

A review of more than 200 studies reveals that olfactory receptors--proteins that bind to odors that aid the sense of smell--perform a wide range of mostly unknown functions outside the nose.

12 Jul 2018

New biosensor could enable early non-invasive diagnosis of Alzheimer's disease through magnetic resonance imaging

UPM researchers are involved in the development of a new biosensor that can be useful to achieve an early non-invasive diagnosis of Alzheimer's disease using magnetic resonance imaging.

12 Jul 2018

Blood telomeres can help predict risk of disease worsening or death in COPD patients

Some patients with COPD demonstrate signs of accelerated aging. In a new study published in the journal CHEST researchers report that measuring blood telomeres, a marker of aging of cells, can be used to predict future risk of the disease worsening or death.

12 Jul 2018

New study identifies inherited genetic variants that raise risk of clonal hematopoiesis

A new study led by researchers at Harvard Medical School and the Harvard T.H. Chan School of Public Health has identified some of the first known inherited genetic variants that significantly raise a person's likelihood of developing clonal hematopoiesis, an age-related white blood cell condition linked with higher risk of certain blood cancers and cardiovascular disease.

12 Jul 2018

Study shows short-term improvements in blood vessel function after consuming red raspberries

A recent randomized controlled trial, published in the Archives of Biochemistry and Biophysics, provides insights on the promising outcomes of short-term improvements in blood vessel function among healthy males who consumed dietary achievable amounts of red raspberries.

11 Jul 2018

Targeting amino acid transporter may improve survival rates for non-small cell lung cancer patients

An amino acid transporter named xCT may affect the growth and progression of non-small cell lung cancer, a discovery that may predict the five-year survival rate of patients suffering from this cancer, now at 16 percent, researchers at Georgia State University and Vanderbilt University Medical Center have concluded.

11 Jul 2018

Altitude sickness drug may offer significant gains for patients with glioblastoma

A drug used to treat altitude sickness -- as well as glaucoma, epilepsy, heart failure and seizures -- may also offer significant gains for patients with a fast-growing brain tumor known as glioblastoma, according to a study published July 4, 2018, in the journal Science Translational Medicine.

10 Jul 2018

Biomarker News and Research

Further Reading

Study: Blood test can predict response of advanced prostate cancer patients to treatments

MODEL-AD Center releases eight new mouse models for Alzheimer's research

Scientists create wearable device that measures cortisol in sweat

ECU researchers develop world’s first blood test that detects melanoma in its early stages

Top AI companies join hands to discover novel drugs for DMD

Scientists identify melanoma biomarkers that could help tailor immunotherapy treatments

Mother's microbiome determines offspring's risk of developing autism

Conservative management of lung subsolid nodules reduces overtreatment and unnecessary surgery

Traumatic brain injury biomarker could help predict patient prognosis

Four-protein biomarker blood test improves lung cancer risk assessment for smokers

Olfactory receptors perform a range of unknown functions outside the nose, reveals study

New biosensor could enable early non-invasive diagnosis of Alzheimer's disease through magnetic resonance imaging

Blood telomeres can help predict risk of disease worsening or death in COPD patients

New study identifies inherited genetic variants that raise risk of clonal hematopoiesis

Study shows short-term improvements in blood vessel function after consuming red raspberries

Targeting amino acid transporter may improve survival rates for non-small cell lung cancer patients

Altitude sickness drug may offer significant gains for patients with glioblastoma

Targeting multiple proteins may be key to treat neurodegenerative disorders

Researchers discover genetic marker associated with salt sensitivity of blood pressure

Mount Sinai study identifies potential new treatment target for aggressive bladder cancer

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