Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Alzheimer’s-in-a-dish model made better with microfluidic system

Researchers from Massachusetts have used a microfluidic device to incorporate neuroinflammation into the Alzheimer's-in-a-dish model for drug discovery.

31 Jul 2018

Research may help advance search for more effective drugs to treat Alzheimer's disease

Two new studies published by investigators from Brigham and Women's Hospital illustrate that not all forms of amyloid-beta protein - the protein thought to initiate Alzheimer's disease - play an equally menacing role in the progress of the disease.

31 Jul 2018

Computational platform predicts how to convert one cell type into another

Researchers have developed a computational platform that predicts how one subtype of cells can be converted into another subtype.

30 Jul 2018

Researchers discover stem cell that allows geckos to create new brain cells

University of Guelph researchers have discovered the type of stem cell allowing geckos to create new brain cells, providing evidence that the lizards may also be able to regenerate parts of the brain after injury.

28 Jul 2018

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended broadening the existing marketing authorization for Darzalex® for use as frontline therapy.

28 Jul 2018

DFG to honor two researchers with Ursula M. Händel Animal Welfare Prize

Prof. Dr. Ellen Fritsche, a toxicologist from the Leibniz Research Institute for Environmental Medicine at Heinrich Heine University Düsseldorf, and PD Dr. Dr. Hamid Reza Noori, a mathematician, physicist and medical scientist from the Max Planck Institute for Biological Cybernetics in Tübingen, are to be presented with the Ursula M. Händel Animal Welfare Prize by the Deutsche Forschungsgemeinschaft.

27 Jul 2018

OHSU researchers discover disease in monkeys that mimics childhood neurodegenerative disorder

OHSU scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people - a finding that holds promise for developing new gene therapies to treat Batten disease.

27 Jul 2018

Targeting mossy cells may offer new strategy for treating brain disorders

A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.

27 Jul 2018

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Researchers have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder.

27 Jul 2018

Scientists take important step to understand mechanisms that cause Huntington's disease

The neuroscientist Dr David Vilchez and his team at CECAD, the University of Cologne's Cluster of Excellence for Aging Research, have made an important step towards understanding the mechanisms that cause the neurodegenerative disorder Huntington's disease.

27 Jul 2018

CNDA approves KEYTRUDA for treatment of advanced melanoma

Merck, known as MSD outside the United States and Canada, today announced that KEYTRUDA, Merck's anti-PD-1 therapy, has been approved by the China National Drug Administration for the treatment of adult patients with unresectable or metastatic melanoma following failure of one prior line of therapy.

26 Jul 2018

Cutting-edge laboratory technique recapitulates brain development more accurately than ever

A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever, according to a new study from Case Western Reserve University School of Medicine.

26 Jul 2018

Disrupted transportation routes in nerve cells are main cause of Parkinson's disease

'Traffic jams' can also occur in the brain and they can be damaging. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg have been able to confirm that this is the case.

26 Jul 2018

Research provides new roadmap for repairing damaged brain cells in multiple sclerosis

Research published today in the journal Nature provides new understanding about how drugs can repair damaged brain cells that cause disability in patients with multiple sclerosis.

26 Jul 2018

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Omeros Corporation announced today that the European Medicines Agency's Committee for Orphan Medicinal Products issued a positive opinion recommending orphan drug designation of OMS721 for treatment in hematopoietic stem cell transplantation.

25 Jul 2018

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Merck, known as MSD outside the United States and Canada, announced today that the pivotal Phase 3 KEYNOTE-048 trial investigating KEYTRUDA, Merck's anti-PD-1 therapy, for first-line treatment of recurrent or metastatic head and neck squamous cell carcinoma, met a primary endpoint of overall survival as monotherapy in patients whose tumors expressed PD-L1.

25 Jul 2018

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

Researchers at the RIKEN Center for Integrative Medical Science in Japan have discovered how antibodies secreted in the gut promote the growth of beneficial bacteria.

25 Jul 2018

Researchers study whole genome sequences of human induced pluripotent stem cells

The therapeutic potential of human induced pluripotent stem cells, which are capable of becoming almost any type of cell in the human body, is well-recognized and broadly pursued, but their mutational burden has not been fully characterized yet.

25 Jul 2018

Mutational burden of stem cells studied to improve disease models and therapies

Researchers from the University of California have characterized the mutational burden of human induced pluripotent stem cells (iPSCs), potentially improving researchers’ ability to prioritize stem cell lines for models of human disease and/or therapies.

25 Jul 2018

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

A signaling pathway that helps promote normal cell growth worsens a form of leukemia by taking control of another pathway better known for protecting cells from biological stress, a new study shows.

24 Jul 2018

Stem Cells News and Research

Further Reading

Alzheimer’s-in-a-dish model made better with microfluidic system

Research may help advance search for more effective drugs to treat Alzheimer's disease

Computational platform predicts how to convert one cell type into another

Researchers discover stem cell that allows geckos to create new brain cells

Janssen’s Darzalex receives positive CHMP opinion for treating multiple myeloma patients

DFG to honor two researchers with Ursula M. Händel Animal Welfare Prize

OHSU researchers discover disease in monkeys that mimics childhood neurodegenerative disorder

Targeting mossy cells may offer new strategy for treating brain disorders

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Scientists take important step to understand mechanisms that cause Huntington's disease

CNDA approves KEYTRUDA for treatment of advanced melanoma

Cutting-edge laboratory technique recapitulates brain development more accurately than ever

Disrupted transportation routes in nerve cells are main cause of Parkinson's disease

Research provides new roadmap for repairing damaged brain cells in multiple sclerosis

Omeros’ OMS721 receives positive opinion from EMA's COMP for treating hematopoietic stem cell transplant

Phase 3 study of KEYTRUDA monotherapy meets primary endpoint

Researchers discover how antibodies secreted in the gut promote growth of healthy microbiome

Researchers study whole genome sequences of human induced pluripotent stem cells

Mutational burden of stem cells studied to improve disease models and therapies

'Hijacked' cell response to stress reveals potential therapeutic targets for leukemia

eBook: Integrated solutions for mesenchymal stem cell research and culture eBook

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