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Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Researchers reviewed messenger ribonucleic acid (mRNA) technology and highlighted its clinical applications.

11 May 2022

Susceptibility of four SARS-CoV-2 Omicron sub-lineages to vaccines and monoclonal antibodies

Researchers demonstrated that four SARS-CoV-2 Omicron sub-lineages, BA.1, BA.1.1, BA.2, and BA.3, are resistant to current COVID-19 vaccines and antibody therapeutics to varying extents.

11 May 2022

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

In a recent study posted to the bioRxiv* preprint server, researchers reported that nanoparticles could prevent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry.

10 May 2022

Tumors release lactate to force neighboring cells into supporting cancer growth

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine.

10 May 2022

Postnatal gene therapy may be able to prevent or reverse deadly effects of Pitt-Hopkins syndrome

UNC School of Medicine Scientists have shown for the first time that postnatal gene therapy may be able to prevent or reverse many deleterious effects of a rare genetic disorder called Pitt-Hopkins syndrome.

10 May 2022

Severe symptoms result in high titers of SARS-CoV-2 antibodies

Scientists have focused on determining the cause-effect relationship between SARS-CoV-2 antibody titers and COVID-19 disease severity.

9 May 2022

T cell behavior informs metastatic melanoma outcomes

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn't work, and new research may help explain why.

9 May 2022

Mathematical modeling reveals important factors that govern the effectiveness of adaptive therapy

Most cancer treatments are based on using the maximum tolerated dose of a drug to kill as many cancer cells as possible.

9 May 2022

Research suggests a new approach to treating Glioblastoma Multiforme in adults

Findings from a seven-year research project suggests that there could be a new approach to treating one of the most common and devasting forms of brain cancer in adults - Glioblastoma Multiforme (GBM).

9 May 2022

Study reveals why some lungs are protected against COVID

COVID-19 vaccines have saved at least a million lives in the United States alone, but for many people, a lingering fear remains: if - or when - they get hit by the coronavirus, just how bad will it be? Will they breeze through with little more than a sore throat - or will it saddle them with long-term complications, perhaps even push them to the brink of death?

6 May 2022

Scientists explore immunopathology of COVID-19

Researchers explored the interactions between severe acute respiratory syndrome coronavirus 2 and the host in the development of COVID-19.

6 May 2022

Marine bioactive compounds against SARS-CoV-2

A new review paper published in the journal Environmental Science and Pollution Research aimed to determine the possibilities of using biologically active compounds derived from various chemical classes of marine organisms against SARS-CoV-2 infection at various stages of the life cycle of the virus.

6 May 2022

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

A recent study posted to the bioRxiv* preprint server demonstrated that the latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages evade immunity imparted by the prior subvariants.

5 May 2022

Study supports daily steroid doses for children with Duchenne muscular dystrophy

New research published in JAMA recommends daily steroid doses for children with Duchenne muscular dystrophy (DMD), marking a significant change in how the disease is treated.

4 May 2022

Discovery could lead to new treatments to minimize cravings in people with addictions

For some people with alcohol use disorder, it might be the sight of a familiar bar or a favorite bottle; for others, it might be the feeling of leaving the office after a stressful day at work or stepping into a crowded party. Most people who struggle with drug or alcohol addiction have particular cues that set off their cravings.

4 May 2022

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Elevated levels of an enzyme called PHGDH in the blood of older adults could be an early warning sign of Alzheimer's disease, and a study led by the University of California San Diego provides new evidence to support this claim.

4 May 2022

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

A newly published analysis in the Journal of the American College of Cardiology1 of hospitalized patients with both a severe type of heart attack called STEMI (ST-elevation myocardial infarction) and coronavirus disease-19 (COVID-19) infection compares clinical outcomes for these patients during the first and second years of the COVID-19 pandemic.

3 May 2022

Therapeutics News and Research

Review portrays clinical journey of messenger RNA vaccines and mRNA-based therapies

Susceptibility of four SARS-CoV-2 Omicron sub-lineages to vaccines and monoclonal antibodies

Decoy ACE2 nanoparticles block the entry of SARS-CoV-2 into cells

Tumors release lactate to force neighboring cells into supporting cancer growth

Postnatal gene therapy may be able to prevent or reverse deadly effects of Pitt-Hopkins syndrome

Severe symptoms result in high titers of SARS-CoV-2 antibodies

T cell behavior informs metastatic melanoma outcomes

Mathematical modeling reveals important factors that govern the effectiveness of adaptive therapy

Research suggests a new approach to treating Glioblastoma Multiforme in adults

Study reveals why some lungs are protected against COVID

Scientists explore immunopathology of COVID-19

Marine bioactive compounds against SARS-CoV-2

SARS-CoV-2 Omicron BA.2.12.1, BA.4 and BA.5 subvariants are superior to their predecessors

Study supports daily steroid doses for children with Duchenne muscular dystrophy

Discovery could lead to new treatments to minimize cravings in people with addictions

Elevated levels of PHGDH enzyme associated with Alzheimer’s disease pathology

Study reveals trends in clinical characteristics and outcomes of STEMI patients with COVID-19

Studying immunomodulatory effects of microbiota helps design prophylactic and therapeutic interventions against COVID-19

New method enables the structural analysis of RNA molecules

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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