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NIH launches precision medicine trial to test new treatments for myeloid cancers

The National Institutes of Health (NIH) has launched a proof-of-concept precision medicine clinical trial to test new treatment combinations targeting specific genetic changes in the cancer cells of people with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

23 Oct 2024

Rise in weight-management glucose-lowering drug prescriptions in type 1 diabetes patients

From 2010 to 2023, GLP-1RAs and SGLT2 inhibitors saw rising prescriptions in type 1 diabetes, particularly for patients with obesity and cardiorenal risks.

23 Oct 2024

Human midbrain organoids: A promising tool in the fight against Parkinson's disease

Advancements in organoid technology are crucial for Parkinson's disease research, providing human-relevant models for studying disease and testing therapies.

23 Oct 2024

P-stalk ribosomes identified as key regulators of immune evasion in cancer

Research uncovers how P-stalk ribosomes regulate cytokine responses, driving immune evasion in tumors across multiple cancer types. It offers new insights into post-translational mechanisms influencing immunotherapy success.

23 Oct 2024

Advancements in antibody-drug conjugates transform cancer therapy

Antibody-drug conjugates (ADCs) have emerged as a promising approach in cancer therapy, offering a 'magic bullet' strategy that combines the precision of monoclonal antibodies with the potency of cytotoxic drugs.

22 Oct 2024

Scurvy may be making a comeback amid economic strain

The scourge of scurvy, which is caused by vitamin C deficiency, may be re-emerging amid the cost of living crisis and the rise in weight loss (bariatric) surgery, suggest doctors in the journal BMJ Case Reports after treating a middle-aged man with the condition.

22 Oct 2024

Study links schizophrenia to increased risk of sudden cardiac death

The lifetime risk of an unexpected and sudden death from a cardiovascular cause in the absence of pre-existing heart disease - known as sudden cardiac death - is more than 4 times higher for people with schizophrenia than it is for the general population, indicates Danish research published online in the journal Heart.

22 Oct 2024

New drug WNTinib shows promise in treating pediatric liver cancer

A new drug called WNTinib can delay the growth of tumors and improve survival in hepatoblastoma, a type of liver cancer that occurs in young children.

22 Oct 2024

Study highlights life-saving potential of access to effective obesity treatments

Expanding access to new, highly effective weight-loss medications could prevent more than 40,000 deaths a year in the United States, according to a new study led by researchers at Yale School of Public Health and the University of Florida.

22 Oct 2024

FDA funding fuels research on turkey parasite and potential treatments

As scientists learn more about a deadly parasite's ability to move from host to host in turkey flocks, a long-standing theory is in question and opens the door to new preventative measures.

22 Oct 2024

Cutting off cancer cells' access to fats may enhance cancer therapy

Cutting off cancer cells' access to fat may help a specific type of cancer treatment work more effectively, reports a study by Van Andel Institute scientists.

22 Oct 2024

Senolytic agents show promise in mouse model of pelvic organ prolapse

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 19 on September 26, 2024, entitled, "Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model."

22 Oct 2024