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Seroprevalence study reveals high exposure to SARS-CoV-2 in Bangui population

Researchers performed a cross-sectional study in the city of Bangui, the capital of the Central African Republic from July 12, 2021, to August 20, 2021.

28 Nov 2021

SARS-CoV-2 Omicron variant: What we know so far

On November 24, 2021, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant was first reported to the World Health Organization (WHO) from South Africa.

28 Nov 2021

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

A study developed a protein-based subunit vaccine, PHH-1V, that consisted of a recombinant RBD fusion heterodimer of the alpha) and beta variants of SARS-CoV-2.

26 Nov 2021

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

A combination of two targeted cancer drugs showed unprecedented, "clinically meaningful" activity in patients with highly malignant brain tumors that carried a rare genetic mutation, according to a clinical trial report by investigators from Dana-Farber Cancer Institute.

25 Nov 2021

COVID-19 vaccine boosters to prevent breakthrough SARS-CoV-2 infections in healthy adults

Researchers measured anti-RBD IgG and virus neutralization before and after vaccination with boosters.

25 Nov 2021

Safety and immunogenicity of COVID-19 peptide vaccine

In a study published in Nature, researchers from University Hospital Tübingen have been investigating the results from a Phase I trial for a new vaccine against SARS-CoV-2 variants.

25 Nov 2021

SARS-CoV-2 Delta variant mutation sites

A new review article dissected the sites of mutation in the RBD of the Delta variant and other variants of concern and variants of alert and interest.

25 Nov 2021

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

In this perspective, a new study published on the medRxiv* preprint server analyzed the clinical efficacy of two serum antigen tests to identify SARS CoV-2 infection and evaluate the kinetics of serum nucleocapsid (N) antigen in severe and non-severe patients for disease severity prediction.

24 Nov 2021

Can COVID-19 affect erectile function?

Researchers discuss the underlying mechanisms through which COVID-19 can affect erectile function.

24 Nov 2021

Acute SARS-CoV-2 infection during pregnancy associated with placental ACE2 shedding

A new study, published on the bioRxiv* preprint server, hypothesized that ACE-2 expression and ADAM17 activity in the placenta is affected by the timing of SARS-CoV-2 infection of the mother.

24 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Study finds rhinovirus reduces SARS-CoV-2 replication in airway epithelial cells

A recent study has demonstrated that SARS-CoV-2 infection induces a significantly lower interferon response than rhinovirus infection.

24 Nov 2021

Antibody persistence in infants after maternal COVID-19 vaccination

New research finds COVID-19 vaccination during pregnancy results in significantly greater antibody persistence in the infants compared to natural infection of the mothers during pregnancy.

24 Nov 2021

Bat coronavirus ecology, evolution, and spillover

In a review published in Nature Reviews Microbiology, the authors collate information about the ecology and evolution of bat coronaviruses.

24 Nov 2021

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

A new combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson's disease-afflicted brain cells, according to a Northwestern Medicine study published in Neuron.

23 Nov 2021

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Scientists utilize N. benthamiana for producing the N-protein and an antigenic cocktail containing the N-protein and SARS-CoV-2 S RBD.

23 Nov 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

An increase in the half-life of remdesivir for COVID-19 treatment

In this study, researchers analyzed several drug candidates to investigate their efficacy against a broad spectrum of coronaviruses in cell culture studies.

23 Nov 2021

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells.

22 Nov 2021

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection.

22 Nov 2021

Enzyme News and Research

Seroprevalence study reveals high exposure to SARS-CoV-2 in Bangui population

SARS-CoV-2 Omicron variant: What we know so far

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

Combination of two targeted drugs shows "clinically meaningful" activity in some malignant brain tumors

COVID-19 vaccine boosters to prevent breakthrough SARS-CoV-2 infections in healthy adults

Safety and immunogenicity of COVID-19 peptide vaccine

SARS-CoV-2 Delta variant mutation sites

Serum SARS-CoV-2 antigen: A better predictor of COVID-19 severity

Can COVID-19 affect erectile function?

Acute SARS-CoV-2 infection during pregnancy associated with placental ACE2 shedding

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Study finds rhinovirus reduces SARS-CoV-2 replication in airway epithelial cells

Antibody persistence in infants after maternal COVID-19 vaccination

Bat coronavirus ecology, evolution, and spillover

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

An increase in the half-life of remdesivir for COVID-19 treatment

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

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