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GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

A synthetic molecular code shows promise towards improving the response of some cancer patients to immunotherapy treatments.

14 Sep 2021

Artemisia plant extract prevents SARS-CoV-2 replication in vitro

A new study describes the beneficial effect of an extract of Artemisia annua when used to treat cells in culture exposed to SARS-CoV-2.

13 Sep 2021

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

A recent study examined the ability of SARS-CoV-2 to impact DNA damage response and telomere stability in Vero E6 cells.

13 Sep 2021

Complement factor C1q may play a role in the secondary effects of mild traumatic brain injury

After mild traumatic brain injury (TBI), a molecule called complement factor C1q may play a role in the secondary effects of brain injury, such as sleep disruption, epileptic activity, and inflammation, according to a new study in mice.

13 Sep 2021

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

The presence of special immune system defense molecules, called autoimmune antibodies, has been strongly tied to how poorly people fare when hospitalized with COVID-19, a new study shows.

9 Sep 2021

Cellular program could turn T cells into effective cancer killers

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

9 Sep 2021

Optibrium Releases 3D Ligand-based Design Module for StarDrop Drug Discovery Software

Optibrium Ltd today announced the release of the latest version of StarDrop™, its comprehensive software platform for small molecule design.

From Optibrium Ltd. 9 Sep 2021

Allergic reactions provide protection against yeast-triggered asthma, research shows

We think of asthma and other allergic diseases as unnecessary aberrant immune responses that do more harm than good. However, new evidence by an international team led by researchers at Baylor College of Medicine shows that some allergic reactions provide necessary protection against highly invasive and potentially lethal infectious agents, such as yeast.

9 Sep 2021

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers to safely and effectively treat neuropathic pain.

8 Sep 2021

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

About a quarter of the world's population is infected with tuberculosis bacteria, according to the World Health Organization, but only about 5 to 10% of those infected will develop symptoms. These pathogens are mycobacteria, which are everywhere, including in chlorine-treated tap water.

8 Sep 2021

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

A new study successfully identifies a series of inhibitors that possesses pancoronavirus activity against SARS-CoV, SARS-CoV-2, and MERS-CoV.

7 Sep 2021

Researchers find potential new target for treating systemic inflammation in obesity

A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity.

7 Sep 2021

Researchers develop the smallest CRISPR to date for genome editing

A compact and efficient CRISPR-Cas system, named CasMINI, could be broadly useful for cell-engineering and gene-therapy applications because it is easier to deliver into cells. The findings appear in a study publishing September 3 in the journal Molecular Cell.

4 Sep 2021

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he thinks it's time to reimagine CRISPR as a Swiss Army knife.

4 Sep 2021

UTSA receives $3.2 million CPRIT grant for developing new approach to fight against cancer

The University of Texas at San Antonio has been awarded a five-year $3.2 million grant from the Cancer Prevention & Research Institute of Texas.

2 Sep 2021

UCD spin-out company secures €595k in seed funding to advance drug development

BioSimulytics (www.biosimulytics.ai), a University College Dublin (UCD) spin-out company, today announced that it has secured €595k in initial seed funding from a number of strategic angel investors and Enterprise Ireland.

2 Sep 2021

Novel molecular device exhibits exceptional computing prowess

In a discovery published in the journal Nature, an international team of researchers has described a novel molecular device with exceptional computing prowess.

2 Sep 2021

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Sepsis is the leading cause of death in Brazil's intensive care units (ICUs). Among patients who progress to the severe form of the disease, 40% die, and the survivors often suffer from cardiovascular and neurological complications, as well as a significant decline in immunity lasting for years after they are discharged from hospital.

2 Sep 2021

Uppsala researchers find solution to long-standing biological search enigma

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university have now discovered the solution; it is easier to find a rope than a ball if you are blindfolded.

1 Sep 2021

Molecule News and Research

GIST researchers unravel coordination mechanism of base excision repair

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

Artemisia plant extract prevents SARS-CoV-2 replication in vitro

SARS-CoV-2 may have consequences to host cells beyond evoking an immune response

Complement factor C1q may play a role in the secondary effects of mild traumatic brain injury

Autoimmune antibodies strongly linked to the severity of illness in COVID-19 patients

Cellular program could turn T cells into effective cancer killers

Optibrium Releases 3D Ligand-based Design Module for StarDrop Drug Discovery Software

Allergic reactions provide protection against yeast-triggered asthma, research shows

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Molecular underpinning of chronic bone infection in patients with mycobacterial disease revealed

Potential pancoronavirus fusion inhibitors that are effective against SARS-CoV-2 variants

Researchers find potential new target for treating systemic inflammation in obesity

Researchers develop the smallest CRISPR to date for genome editing

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

UTSA receives $3.2 million CPRIT grant for developing new approach to fight against cancer

UCD spin-out company secures €595k in seed funding to advance drug development

Novel molecular device exhibits exceptional computing prowess

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Uppsala researchers find solution to long-standing biological search enigma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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