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New modeling study evaluates impact of COVID-19 in low- and middle-income countries

A new modeling study evaluating unfolding COVID-19 epidemics among different income countries reports that, in lower income countries, even if risk is reduced because populations are younger, this benefit is largely negated by limited health system capacity and closer inter-generational contact.

12 Jun 2020

Activating specific brain cells can trigger hibernation-like state in mice

In Sci-Fi movies, astronauts often enter an inactive state in "hibernation chambers" to cross the vastness of space.

12 Jun 2020

Human cardiac organoids for modeling physiological conditions during a heart attack

In the U.S., someone has a heart attack every 40 seconds, and yet researchers have not had a model that fully mimics what occurs in the human heart after a heart attack.

12 Jun 2020

Does COVID-19 injure the placenta of pregnant women?

News-Medical speaks to Dr. Jeffery Goldstein about whether COVID-19 is damaging the placentas of pregnant women and what women can do to protect themselves.

12 Jun 2020

Scientists develop a lead compound to fight chemotherapy-resistant prostate cancer

Scientists of Far Eastern Federal University, together with German and Russian colleagues, have developed a lead compound to fight chemotherapy-resistant prostate cancer.

12 Jun 2020

Rice lab's fluorescent tag project reveals new method to kill tumors

A Rice University lab's project to make better fluorescent tags has turned into a method to kill tumors. Switching one atom in the tag does the trick.

11 Jun 2020

Race-related differences in genetic determinants of COVID-19 severity

Researchers at the University of Iowa have identified differences in gene expression levels between African Americans and European Americans that may explain the disproportionately higher rates of coronavirus disease 2019 (COVID-19) cases and related deaths among African Americans.

11 Jun 2020

A family with five doctors — and two COVID deaths

On the morning of April 1, Dr. Priya Khanna inched her way from the bedroom to the front door, using walls, doors and railings to hold herself up long enough to get to the stretcher waiting outside. She had been battling COVID-19 for five days and was struggling to breathe.

11 Jun 2020

Hydroxychloroquine suppresses 'trained immunity'

A new study published on the preprint server medRxiv in June 2020 shows that the drug hydroxychloroquine (HCQ) suppresses a form of immunity called ‘trained immunity,’ with repercussions for its potential use to treat COVID-19.

11 Jun 2020

Decisions made for incapacitated patients often not compatible with care requested by families

Researchers from Regenstrief Institute and Indiana University report that nearly half of the time medical treatments and orders received for incapacitated patients were not compatible with goals of care requested by their surrogate decision makers.

10 Jun 2020

Anticardiolipin antibodies and COVID-19

A new study has shown that anticardiolipin antibodies are associated with the novel coronavirus infection or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19.

10 Jun 2020

Indirect viral infection of the kidneys by SARS-CoV-2-induced inflammatory reaction

SARS-CoV-2-associated acute kidney injury is not uncommon. Many hospitalized COVID-19 patients - as many as 80% of critically ill COVID-19 patients, according to a current study - develop acute kidney injury, but without requiring dialysis in most cases. Proteinuria and hematuria are present in about half the cases.

8 Jun 2020

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

Photodynamic therapy can be used in many types and localizations of tumors

As co-author, Research Associate Ayrat Bilyalov explains, the work on photodynamic therapy has been ongoing for 5 years. The group comprises medical professionals from Kazan Federal University and Medical Center of the Presidential Administration of Kazakhstan.

8 Jun 2020

Tocilizumab in COVID-19 patients on mechanical ventilation

Now, a new study by researchers from the University of Michigan and published on the online preprint server medRxiv* in June 2020 shows that the cytokine inhibitor tocilizumab could have a favorable effect on survival in the most severely infected patients who require mechanical ventilation. This needs to be confirmed by clinical trials.

7 Jun 2020

Kidney enzyme renalase a potential therapy for severe COVID-19

Researchers from Yale School of Medicine have discovered that a low blood level of an enzyme called renalase is associated with severe coronavirus disease 2019 (COVID-19).

7 Jun 2020

Approved drug could help dampen massive immune response associated with severe COVID-19

The drug acalabrutinib, FDA-approved for the treatment of several types of B cell cancers, improved the oxygenation levels and decreased molecular markers of inflammation in a majority of 19 patients hospitalized for the treatment of severe COVID-19, according to a new study by Mark Roschewski and colleagues.

5 Jun 2020

New fluorescent dye may prove useful for biomedical imaging applications

Scientists can monitor biomolecular processes in live tissue by noninvasive optical methods, such as fluorescence imaging.

5 Jun 2020

Newborn screening guidelines updated for critical congenital heart disease

A distinguished panel of medical experts, state and federal health officials, and congenital heart disease parent advocates published recommended updates to the current American Academy of Pediatrics' protocol for detecting critical congenital heart disease (CCHD) in newborn babies using pulse oximetry.

4 Jun 2020

Study says vitamin-magnesium combo may reduce severity of COVID-19 in seniors

The COVID-19 pandemic that began in late December 2019 has spread to over 188 countries and territories, causing over 6.5 million cases and 385,000 deaths. With no effective therapeutic COVID-19 drug or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in sight, researchers are exploring different strategies to limit its spread and mortality.

4 Jun 2020

Oxygen News and Research

New modeling study evaluates impact of COVID-19 in low- and middle-income countries

Activating specific brain cells can trigger hibernation-like state in mice

Human cardiac organoids for modeling physiological conditions during a heart attack

Does COVID-19 injure the placenta of pregnant women?

Scientists develop a lead compound to fight chemotherapy-resistant prostate cancer

Rice lab's fluorescent tag project reveals new method to kill tumors

Race-related differences in genetic determinants of COVID-19 severity

A family with five doctors — and two COVID deaths

Hydroxychloroquine suppresses 'trained immunity'

Decisions made for incapacitated patients often not compatible with care requested by families

Anticardiolipin antibodies and COVID-19

Indirect viral infection of the kidneys by SARS-CoV-2-induced inflammatory reaction

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Photodynamic therapy can be used in many types and localizations of tumors

Tocilizumab in COVID-19 patients on mechanical ventilation

Kidney enzyme renalase a potential therapy for severe COVID-19

Approved drug could help dampen massive immune response associated with severe COVID-19

New fluorescent dye may prove useful for biomedical imaging applications

Newborn screening guidelines updated for critical congenital heart disease

Study says vitamin-magnesium combo may reduce severity of COVID-19 in seniors

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