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Blood test for tumor DNA may predict melanoma recurrence

Monitoring blood levels of DNA fragments shed by dying tumor cells may accurately predict skin cancer recurrence, a new study shows.

15 Apr 2025

Study reveals a potential breakthrough in treating osteonecrosis of the femoral head

A recent study has uncovered a potential breakthrough in treating osteonecrosis of the femoral head (ONFH), a debilitating bone disease that causes severe pain and joint collapse.

15 Apr 2025

UVA scientist secures funding to use sound waves for breast cancer therapy

University of Virginia researcher Natasha D. Sheybani, PhD, has received $5.5 million from the federal Department of Defense to support her cutting-edge efforts to use focused sound waves to improve our immune system's ability to battle breast cancer.

15 Apr 2025

Reserpine shows promise in treating retinitis pigmentosa in rat studies

New studies in rats suggest the drug reserpine, approved in 1955 for high blood pressure, might treat the blinding disease retinitis pigmentosa.

15 Apr 2025

Inherited genetic variants play crucial role in cancer development and behavior

A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the National Cancer Institute-funded Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with-known as germline genetic variants-play a powerful, underappreciated role in how cancer develops and behaves.

15 Apr 2025

Afternoon could be best time for asthma inhaler, study shows

A mid-afternoon puff could be the best way to get the most out of your asthma inhaler according to a new study led by University of Manchester researchers.

15 Apr 2025

Deportation fears add to mental health problems confronting Colorado resort town workers

When Adolfo Román García-Ramírez walks home in the evening from his shift at a grocery store in this central Colorado mountain town, sometimes he thinks back on his childhood in Nicaragua.

15 Apr 2025

#RareDiseases - The EU Action Plan must step up European-national cooperation

A high-level conference convened in Warsaw under the auspices of the Polish Presidency of the Council of the European Union highlighted the importance of adopting a comprehensive Europe-wide policy framework on rare diseases.

15 Apr 2025

Lithium shifts circadian rhythms early in bipolar disorder and may offer clues to treatment response

A randomized controlled trial shows that lithium treatment in bipolar disorder patients reduces daytime activity, advances its onset time, and increases volatility in circadian rest-activity patterns. These changes appear early and independently of mood, offering promise as early biomarkers of treatment response.

14 Apr 2025

Early combination therapy after heart attack reduces risk of recurrence and death

Cardiovascular disease is by far the most common cause of death worldwide, and myocardial infarction is the most common acute event.

14 Apr 2025

Stress and depression help explain intertwined alcohol, sleep problems

Insomnia and hazardous drinking are so closely intertwined that estimates suggest at least one-third, and as many as 91%, of people who have a hard time with sleep also misuse alcohol.

14 Apr 2025

Gut imbalances in autism linked to brain and behavior changes

A new USC study suggests that gut imbalances in children with autism may create an imbalance of metabolites in the digestive system - ultimately disrupting neurotransmitter production and influencing behavioral symptoms.

14 Apr 2025

Northwestern scientists identify key genes behind Parkinson's development

A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also carry such variants do not.

11 Apr 2025

UVA researcher wins major grant to revolutionize breast cancer treatment

A promising approach to achieve safer, more effective, and more precise breast cancer treatment has earned a University of Virginia researcher a new $5.5 million grant.

11 Apr 2025

Boosting tumor-infiltrating lymphocyte therapy with the power of B cells

Researchers at Moffitt Cancer Center have found that tapping into the body's own immune system and activating a type of immune cell known as B cells, could be the key to boosting the effectiveness of tumor-infiltrating lymphocyte, or TIL therapy.

11 Apr 2025

COVID-19 treatments show minimal serious side effects

Numerous treatment options for COVID-19 have been approved by the U.S. Food and Drug Administration over the last four years, including antiviral drugs and monoclonal antibodies that suppress an excessive immune response.

11 Apr 2025

GSK3β identified as a driver of drug resistance in BRAF mutant melanoma

A new research perspective was published in Oncotarget, Volume 16, on April 4, 2025, titled "GSK3β activation is a key driver of resistance to Raf inhibition in BRAF mutant melanoma cells."

11 Apr 2025

Police officers at higher risk of traumatic brain injuries and PTSD

Police officers are more than twice as likely to have traumatic brain injuries compared to the general population. Officers who incur these injuries while on duty face more than double the risk of developing complex post-traumatic stress disorder (PTSD).

11 Apr 2025

New guidelines released for managing hypercholesterolemia in adults over 75

The National Lipid Association (NLA) and the American Geriatrics Society (AGS) have released a Joint Scientific Statement focused on the management of hypercholesterolemia in adults older than 75 years who do not have a history of atherosclerotic cardiovascular disease (ASCVD).

10 Apr 2025