immunity News and Research

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Booster doses provide strong protection against hospitalization and death from COVID-19

Booster doses of mRNA vaccines provided strong protection against hospitalization and death from COVID-19 in Qatar, though breakthrough SARS-CoV-2 infections were greater for the omicron variant compared with the delta variant, according to a study by investigators at Weill Cornell Medicine—Qatar.

30 Mar 2022

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

The subventricular neurogenic niche is a region of the brain where tumor cells can hide from chemotherapy treatment to reappear later, causing relapses in patients with childhood acute lymphoblastic leukemia (ALL), and preventing the formation of new neurons, as demonstrated by research led by Universidad Complutense de Madrid (UCM).

30 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Researchers discuss the use of the isothiocyanate sulforaphane for the treatment of both SARS-CoV-2 and HCoV-OC43 infections.

30 Mar 2022

Understanding COVID-19 vaccine hesitancy and decision-making during pregnancy

In a new study, researchers used a web-based survey to analyze COVID-19 vaccine-related awareness and hesitance in pregnant Californians.

30 Mar 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Researchers demonstrated the inhalation of an ACE2 decoy receptor, sACE22.v2.4-IgG1, increases survival and ameliorates lung injury in K18-hACE2 transgenic mice.

30 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

A new study reported systemic and mucosal immunity against SARS-CoV-2 via intranasal delivery of a vaccine containing recombinant SARS-CoV-2 antigens, nucleocapsid, and spike subunit.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

A new study shows that multiple variants of this virus may coinfect the same patient, using both genomic sequencing data and computational models.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

Immunity against SARS-CoV-2 BA.1, BA.2, and BA.3 after three doses of BNT162b2 vaccine

A new study assesses the neutralization of three Omicron sublineages by BNT162b2-vaccinated sera collected one month after the third vaccine dose. A preprint version of the study is available on the bioRxiv* server while the article undergoes peer review.

29 Mar 2022

Government provides new guidance for living with COVID

People at risk of serious illness from COVID-19, and eligible for treatments, will continue to get free tests to use if they develop symptoms, along with NHS and adult social care staff and those in other high-risk settings, Health and Social Care Secretary Sajid Javid announced today (Tuesday 29 March).

29 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Researchers analyzed whether repeated vaccinations against COVID-19 increase serological response in non-responding kidney transplant recipients.

29 Mar 2022

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Researchers evaluated the cellular and humoral immunity following heterologous and homologous COVID-19 immunization regimens for up to five months.

29 Mar 2022

Japanese researchers discover new mechanisms of action by extracellular vesicles in lymphoma

Japanese collaborative research teams have discovered new mechanisms of action by extracellular vesicles (EV) for the development and malignant progression of lymphomas.

28 Mar 2022

Virtual reality helps reduce COVID-19 vaccine hesitancy

A new study investigates whether intention for vaccination is increased by a gamified immersive VR experience that shows how community immunity works.

28 Mar 2022

Northwestern scientists continue to advance the understanding of COVID-19

As the COVID-19 pandemic enters its third year, Northwestern Medicine scientists continue to help advance the understanding of the disease and its impact, from investigating antibody protection against COVID-19 reinfection to elevating women in academic research and highlighting racial and ethnic disparities in COVID-19 hospital mortality in Illinois.

28 Mar 2022

immunity News and Research

Booster doses provide strong protection against hospitalization and death from COVID-19

Colonization of subventricular neurogenic niche by leukemia cells prevents the formation of new neurons

Role of SARS-CoV-2 S1 subunit in severe COVID-19

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Understanding COVID-19 vaccine hesitancy and decision-making during pregnancy

A summary of SARS-CoV-2 RNA-protein interactome studies

ACE2 decoy receptor with robust neutralization against Omicron subvariants shows therapeutic potential

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Preclinical investigation of intranasal adjuvanted COVID-19 vaccine

The potential efficacy of nasal nanoparticle COVID-19 vaccines

Study investigates whether coinfection with multiple SARS-CoV-2 variants exists in COVID-19 patients

A ferritin nanoparticle candidate vaccine for COVID

Immunity against SARS-CoV-2 BA.1, BA.2, and BA.3 after three doses of BNT162b2 vaccine

Government provides new guidance for living with COVID

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Immune response dynamics following COVID-19 heterologous and homologous vaccinations

Japanese researchers discover new mechanisms of action by extracellular vesicles in lymphoma

Virtual reality helps reduce COVID-19 vaccine hesitancy

Northwestern scientists continue to advance the understanding of COVID-19

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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