Clinical Trial News and Research

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Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Researchers from the University of Washington (UW), Kenya Medical Research Institute (KEMRI), and Hennepin Healthcare Research Institute (HHRI) announced results at CROI from a clinical trial demonstrating that doxycycline taken after sex does not prevent bacterial sexually transmitted infections (STIs) – chlamydia or gonorrhea – among cisgender women.

20 Feb 2023

Ketamine appears to hold promise in treating cocaine-use disorders

As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder.

20 Feb 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

FAU collaborates with Delray Medical Center, Insightec to fight against Alzheimer's disease

Delray Medical Center is the first hospital in Florida to treat an Alzheimer's disease patient using non-invasive focused ultrasound technology as part of a groundbreaking study being conducted in collaboration with Florida Atlantic University's Institute for Human Health and Disease Intervention (I-Health).

17 Feb 2023

Replacing meat with Quorn's mycoprotein reduces cancer-causing chemicals in the intestines

Researchers from Northumbria University have found that swapping red and processed meat for Quorn's mycoprotein, a fungi-based meat alternative, leads to a significant reduction in intestinal genotoxins - which can cause bowel cancer - and increases healthy gut bacteria.

17 Feb 2023

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Researchers determined the prevalence of antibodies against the SARS-CoV-2 spike glycoprotein following three or more doses of COVID-19 vaccines among immunocompromised individuals.

17 Feb 2023

Most health and nutrition claims on infant formula not supported by robust clinical trial evidence

Most health and nutrition claims on infant formula products seem to be backed by little or no high quality scientific evidence, finds an international survey published by The BMJ today.

16 Feb 2023

Non-invasive FFRCT offers greater accuracy in heart disease diagnosis than other traditional tests

As a patient with a family history of heart disease, Karen Moore has always been diligent about monitoring her heart health.

16 Feb 2023

A new trial to assess if butyrate can prevent colon cancer

Researchers discuss a new clinical trial that will determine the efficacy of butyrate administration in preventing colon cancer.

16 Feb 2023

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Researchers evaluated the effectiveness of nirmatrelvir–ritonavir in preventing coronavirus disease 2019 (COVID-19) severity outcomes during the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant predominance.

16 Feb 2023

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

Patients with resectable non-small cell lung cancer (NSCLC) who were treated with neoadjuvant nivolumab had improved five-year recurrence-free and overall survival rates compared with historical outcomes.

15 Feb 2023

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

The National Institutes of Health has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19.

15 Feb 2023

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

Nutrition researchers at the University of Illinois Chicago studied 80 people with nonalcoholic fatty liver disease and found that those who followed an alternate-day fasting diet and exercised were able to improve their health.

14 Feb 2023

How are changes in coffee and caffeine intake associated with changes in fat tissue?

A recent study published in Clinical Nutrition evaluated the associations between changes in coffee and caffeine consumption and fat tissue changes.

14 Feb 2023

Pediatric telemedicine consults with clinicians in rural, community EDs result in fewer interfacility transfers

Many rural and community emergency departments lack access to pediatric specialty care physicians. So, when an acutely ill child is seen in one of these facilities, they are typically transferred to regional pediatric centers for more comprehensive care.

13 Feb 2023

Do nuts help with type 2 diabetes?

Type 2 diabetes is a metabolic disorder that affects one in ten people worldwide. There has been an alarming increase of 16% in the global prevalence of type 2 diabetes over the past two years.

13 Feb 2023

Neuroprotectant linked to reduced death and disability among stroke patients

The neuroprotectant ApTOLL, a medication that may shield the brain from tissue damage, was linked to reduced death and disability among people being treated for stroke when used with standard treatments to restore blood flow, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2023.

13 Feb 2023

Using blood pressure medications after endovascular treatment for stroke may not be safe or effective

Using blood pressure medications to lower the top number of blood pressure reading (systolic blood pressure) may not be safe or effective among people who have an acute ischemic stroke and undergo a successful mechanical clot removal — endovascular therapy, according to a phase-2 late-breaking clinical trial presented today at the American Stroke Association's International Stroke Conference 2023.

13 Feb 2023

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

The latest generation of antidepressants relieves symptoms by mimicking steroids produced by the brain to ensure neurons are effectively talking to each other.

13 Feb 2023

Research details how the circadian and circannual cycles influence humans at the molecular level

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

13 Feb 2023

Clinical Trial News and Research

Doxycycline taken after sex does not prevent bacterial STIs among cisgender women

Ketamine appears to hold promise in treating cocaine-use disorders

Are SGLT2 inhibitors the next blockbuster drug?

FAU collaborates with Delray Medical Center, Insightec to fight against Alzheimer's disease

Replacing meat with Quorn's mycoprotein reduces cancer-causing chemicals in the intestines

The prevalence of spike-protein antibodies following at least 3 COVID-19 vaccine doses in immunocompromised individuals

Most health and nutrition claims on infant formula not supported by robust clinical trial evidence

Non-invasive FFRCT offers greater accuracy in heart disease diagnosis than other traditional tests

A new trial to assess if butyrate can prevent colon cancer

Nirmatrelvir–ritonavir found to lower COVID-19 severity outcomes

Neoadjuvant nivolumab treatment improves survival rates in NSCLC patients

NIH initiates a clinical trial evaluating an investigational antiviral for treatment of COVID-19

Alternate-day fasting diet and exercise benefit the health of people with nonalcoholic fatty liver disease

How are changes in coffee and caffeine intake associated with changes in fat tissue?

Pediatric telemedicine consults with clinicians in rural, community EDs result in fewer interfacility transfers

Do nuts help with type 2 diabetes?

Neuroprotectant linked to reduced death and disability among stroke patients

Using blood pressure medications after endovascular treatment for stroke may not be safe or effective

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

Research details how the circadian and circannual cycles influence humans at the molecular level

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