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Immune cell betrayal makes aging mice less tolerant of cold temperatures

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body.

1 Sep 2021

Researchers develop new photodynamic therapy for the treatment of deep tumors

Therapies should be highly effective and as free as possible of side effects—a big challenge, particularly in the case of cancer.

1 Sep 2021

Baylor researchers use a faster, more cost-effective technology to discover SARS-CoV-2 inhibitor

Much progress has been made on the development of vaccines aiming at triggering human immunity to SARS-CoV-2, the virus that causes COVID-19. In addition, researchers at Baylor College of Medicine are involved in the development of antiviral drugs to treat infected individuals.

1 Sep 2021

Structure-based model of SARS-CoV-2 spike protein reveals opportunity to halt virus transmission

Scientists have simulated the transition of the SARS-CoV-2 spike protein structure from when it recognizes the host cell to when it gains entry, according to a study published today in eLife.

1 Sep 2021

Innovative AI and simulation tools used to reveal the inner workings of Sar-CoV-2 virus

Argonne, industry and academia collaborate to bring innovative AI and simulation tools to the COVID-19 battlefront.

1 Sep 2021

New low-cost technique helps profile dynamic metabolic features from single isogenic cells

Researchers with the Single-Cell Center, Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences, have developed a fast, low-cost and high-throughput technique capable of profiling dynamic metabolic features from just one isogenic sample of cells.

1 Sep 2021

Researchers employ microbes for storing and retrieving energy from renewable sources

Cornell University bioengineer Buz Barstow is trying to solve a big problem: How to build a low-cost, environmentally friendly and large-scale system for storing and retrieving energy from renewable sources such as wind and solar. Currently, there are no sustainable methods for storing green energy, as batteries are environmentally toxic.

1 Sep 2021

Researchers show how a protein molecular motor can 'constrict' cell membranes

Cells in the human body constantly receive substances from the outside via a process called endocytosis. One important endocytosis pathway involves the formation of a protrusion within the cell membrane, pointing to the inside of the cell, triggered when a molecule needing to get in reaches the membrane.

31 Aug 2021

Scientists identify small compounds that can regulate extracellular vesicle production

Biological vesicles are nano-sized containers that transport proteins and other substances within or between cells.

31 Aug 2021

New compounds offer a two-for-one punch to fight estrogen-sensitive breast cancer

A set of compounds developed by scientists at Scripps Research in Florida target estrogen-sensitive breast cancer cells in new ways, potentially creating better options for patients with treatment-resistant cancers.

31 Aug 2021

Researchers explore the fate of dietary fructose in the body

In today's fast-paced world, the dependence on the widely available "fast" foods and beverages has risen. These foods are typically low in fiber and essential nutrients, and often consist of high amounts of added sugar. This shift in dietary trends, accompanied by a sedentary lifestyle, has been attributed to the rise in various metabolic disorders like diabetes, fatty liver disease, and heart disease.

31 Aug 2021

New, one-stop method developed to avoid de novo genetic disease in embryos

De novo variants (DNVs), genetic mutations that were not previously identifiable in the family history of one of two prospective parents, may cause disease in any children they have.

31 Aug 2021

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Recently, a new study published on the pre-print server bioRxiv* examined the effect that maternal asymptomatic COVID-19 had on decidual and peripheral immune cells during the later stage of pregnancy.

30 Aug 2021

Rice lab receives NIH grant to unravel DNA’s secrets

The poor bacteriophages in Yang Gao's lab are about to have a lot of bad days.

28 Aug 2021

New machine learning techniques help resolve structural biology challenges

Determining the 3D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure – and even such massive efforts are frequently unsuccessful.

27 Aug 2021

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques.

26 Aug 2021

The influence of COVID-19 on platelet activation and aggregation

In a paper recently uploaded to the bioRxiv* preprint server, humanized ACE2 mice are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and platelets are subsequently isolated from the blood for quantitative proteomic analysis.

26 Aug 2021

Researchers identify potential new treatment for osteoarthritis

Osteoarthritis (OA) is a debilitating joint disease that affects millions of individuals worldwide. Common in the older adult population, OA is associated with loss of cartilage over time.

26 Aug 2021

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a growing list of people with several types of cancer, including melanoma, lung cancer, bladder cancer, and many more.

25 Aug 2021

CIRM approves a trio of awards for new stem cell-based projects

The governing Board of the California Institute for Regenerative Medicine has approved a trio of awards, totaling approximately $4 million, to University of California San Diego School of Medicine researchers to advance studies of new stem cell-based treatments for multiple types of cancer and amyotrophic lateral sclerosis (ALS).

25 Aug 2021

Molecule News and Research

Immune cell betrayal makes aging mice less tolerant of cold temperatures

Researchers develop new photodynamic therapy for the treatment of deep tumors

Baylor researchers use a faster, more cost-effective technology to discover SARS-CoV-2 inhibitor

Structure-based model of SARS-CoV-2 spike protein reveals opportunity to halt virus transmission

Innovative AI and simulation tools used to reveal the inner workings of Sar-CoV-2 virus

New low-cost technique helps profile dynamic metabolic features from single isogenic cells

Researchers employ microbes for storing and retrieving energy from renewable sources

Researchers show how a protein molecular motor can 'constrict' cell membranes

Scientists identify small compounds that can regulate extracellular vesicle production

New compounds offer a two-for-one punch to fight estrogen-sensitive breast cancer

Researchers explore the fate of dietary fructose in the body

New, one-stop method developed to avoid de novo genetic disease in embryos

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Rice lab receives NIH grant to unravel DNA’s secrets

New machine learning techniques help resolve structural biology challenges

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

The influence of COVID-19 on platelet activation and aggregation

Researchers identify potential new treatment for osteoarthritis

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

CIRM approves a trio of awards for new stem cell-based projects

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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