Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Today the U.S. Food and Drug Administration granted accelerated approval for Darzalex (daratumumab) to treat patients with multiple myeloma who have received at least three prior treatments. Darzalex is the first monoclonal antibody approved for treating multiple myeloma.

17 Nov 2015

Diets rich in potassium may help prevent heart and kidney problems in patients with type 2 diabetes

Diets rich in potassium may help protect the heart and kidney health of patients with type 2 diabetes, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

13 Nov 2015

Patients with kidney failure at increased risk of developing different types of cancer

For patients with kidney failure, poor kidney function and immunosuppressant medications may increase their risk of developing different types of cancer. The findings, which are published in a study appearing in an upcoming issue of the Journal of the American Society of Nephrology, suggest the need for persistent cancer screening and prevention in these patients.

13 Nov 2015

Researchers find molecular mechanism that may be responsible for development of amyloidoses

A team of local researchers has proposed a molecular mechanism that may be responsible for the development of life-threatening diseases called amyloidoses. The best known of such diseases is Alzheimer's disease (AD), but there are many others that are receiving increased scrutiny, in part because of mounting evidence linking them to atherosclerosis and aging.

13 Nov 2015

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

It's been about a decade since the promise of COX-2 inhibitors -- drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers -- was tempered by the realization that they could cause heart problems in some patients.

13 Nov 2015

Bariatric surgery improves weight, metabolic health and quality of life in adolescents after 3 years

The results of a new study to be published November 6, 2015 in The New England Journal of Medicine to coincide with presentation at The Obesity Society Annual meeting in Los Angeles, California show that three years after undergoing bariatric surgery, adolescents experienced major improvements in their weight, metabolic health, and quality of life.

12 Nov 2015

Child care centers play pivotal role in physical activity levels of preschoolers

A new study published in the American Journal of Preventive Medicine finds child care centers play a pivotal role when it comes to the physical activity levels of preschoolers. Yet few children get to experience outdoor recess time as it is scheduled. Only 3 in 10 children had at least 60 minutes of a full child-care day outdoors for recess, as is recommended by guidelines.

12 Nov 2015

Advances in nanofilter technology may lead to surgically implantable, artificial kidney

Research that could lead to the development of a surgically implantable, artificial kidney, was presented at ASN Kidney Week 2015 November 3-8 at the San Diego Convention Center in San Diego, CA.

11 Nov 2015

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease.

11 Nov 2015

LEO Pharma enters into Asset Purchase Agreement to acquire Astellas’ global dermatology business

LEO Pharma A/S, a global healthcare company dedicated to helping people achieve healthy skin, and Japanese pharmaceutical company Astellas Pharma Inc. today announced that they have entered into an Asset Purchase Agreement under which Astellas will transfer its global dermatology business to LEO Pharma for € 675 million.

11 Nov 2015

Study finds high prevalence of dehydration in older people living in UK care homes

One in every five older people living in UK care homes has dehydration, suggesting that they are not drinking enough to keep themselves healthy.

11 Nov 2015

Small behavioral changes can improve heart health

Improving your heart health may be as simple as making small behavioral changes - a new study of behavioral health interventions suggests that they are effective at helping people alter their lifestyles and lead to physical changes that could improve overall health.

11 Nov 2015

Lowering blood pressure below currently recommended targets reduces risk of stroke, heart attack

Using intensive treatment to lower blood pressure below currently recommended targets significantly reduces rates of major cardiovascular events like stroke and heart attack among a wide range of high-risk patients, according to a large meta-analysis involving almost 45000 individuals, published in The Lancet.

11 Nov 2015

White coat hypertension, masked hypertension increase cardiovascular events over the years

Patients whose blood pressures spikes in the doctor's office but not at home, and patients whose blood pressure spikes at home but not in the doctor's office, suffer more heart attacks, heart failure, and strokes than patients with normal blood pressures in both settings, UT Southwestern Medical Center researchers have found.

10 Nov 2015

Vitamin D deficiency puts people at risk of developing heart problems

A lack of vitamin D can result in weak bones. Recent studies also show that vitamin D deficiency is linked to more serious health risks such as coronary artery disease, heart attacks, and strokes.

10 Nov 2015

Intensive management of high blood pressure reduces rates of cardiovascular disease, lowers risk of death

Jackson T. Wright Jr., MD, PhD, and researchers from University Hospitals Case Medical Center presented new results from the Systolic Blood Pressure Intervention Trial (SPRINT) showing that in patients at high risk for cardiovascular events, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and non-fatal major events or death compared to targeting systolic blood pressure to the usually recommended target of less than 140 mm Hg.

10 Nov 2015

Meat-rich diet may increase kidney cancer risk

A new study indicates that a meat-rich diet may increase the risk of developing kidney cancer through mechanisms related to particular cooking compounds. Also, these associations may be modified by genetic susceptibility to kidney cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study illustrates how diet and genetics may interact to impact cancer risk.

10 Nov 2015

Astellas enters into definitive agreement to acquire Ocata

Astellas Pharma Inc. and Ocata Therapeutics, Inc., a biotechnology company focused on the research and development of new therapies in the field of regenerative medicine, primarily cell therapy addressing unmet medical needs in ophthalmology patients, announced today that they have entered into a definitive agreement.

10 Nov 2015

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

Armaron Bio, a Melbourne-based drug development company focused on heart failure and other diseases, is pleased to announce that it has begun its Phase II clinical trial for NP202, its novel lead candidate drug for heart failure.

9 Nov 2015

New treatment may help patients with chronic renovascular disease

A new treatment may help patients with a chronic kidney condition that can also lead to heart problems and premature death, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

6 Nov 2015

Nephrology News and Research

Further Reading

FDA grants accelerated approval for Darzalex to treat patients with multiple myeloma

Diets rich in potassium may help prevent heart and kidney problems in patients with type 2 diabetes

Patients with kidney failure at increased risk of developing different types of cancer

Researchers find molecular mechanism that may be responsible for development of amyloidoses

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

Bariatric surgery improves weight, metabolic health and quality of life in adolescents after 3 years

Child care centers play pivotal role in physical activity levels of preschoolers

Advances in nanofilter technology may lead to surgically implantable, artificial kidney

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

LEO Pharma enters into Asset Purchase Agreement to acquire Astellas’ global dermatology business

Study finds high prevalence of dehydration in older people living in UK care homes

Small behavioral changes can improve heart health

Lowering blood pressure below currently recommended targets reduces risk of stroke, heart attack

White coat hypertension, masked hypertension increase cardiovascular events over the years

Vitamin D deficiency puts people at risk of developing heart problems

Intensive management of high blood pressure reduces rates of cardiovascular disease, lowers risk of death

Meat-rich diet may increase kidney cancer risk

Astellas enters into definitive agreement to acquire Ocata

Armaron Bio starts Phase 2 trial for novel lead candidate drug for heart failure

New treatment may help patients with chronic renovascular disease

Industry Focus eBook - Cell biology (5th edition) eBook

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Evaluating new approaches for rare disease genomics

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