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Integrated model helps enhance patient care for pediatric brain tumors

The Brain Tumor Center at Children's Hospital Los Angeles is one of the largest and most comprehensive pediatric brain tumor programs in the country, integrating experts from multiple specialty areas into a coordinated treatment team.

2 Feb 2023

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

The Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, was the lead site for a study evaluating Phase I and Phase III clinical trials for elacestrant, a treatment for postmenopausal women and adult men with ER+/HER2- advanced or metastatic breast cancer.

1 Feb 2023

MD Anderson and Federation Bio collaborate to design and manufacture a synthetic microbial consortium

The University of Texas MD Anderson Cancer Center and Federation Bio today announced a strategic collaboration to design and manufacture a complex, synthetic microbial consortium with the goal of expanding the number of cancer patients who respond to immunotherapy.

1 Feb 2023

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

Results from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free survival (PFS) times in patients with triple-negative breast cancer (TNBC) that has a "BRCA-like" phenotype.

31 Jan 2023

New technique offers a two-prong approach to attacking cancers

When noninvasive sound waves break apart tumors, they trigger an immune response in mice. By breaking down the cell wall "cloak," the treatment exposes cancer cell markers that had previously been hidden from the body's defenses, researchers at the University of Michigan have shown.

31 Jan 2023

Researchers develop AI-based strategy for discovering high-affinity antibody drugs

Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.

30 Jan 2023

New biomaterial allows for treating damaged tissue from the inside out

A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair.

30 Jan 2023

MINOCA: Insights into a type of heart attack that predominantly affects women

Heart disease is the leading cause of death among women in the U.S., and a type of heart attack called myocardial infarction with non-obstructive coronary arteries (MINOCA), which predominantly affects women, is garnering increased attention.

30 Jan 2023

Experimental vaccine against Marburg virus shows promise in first-in-human clinical trial

A newly published paper in The Lancet shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial.

30 Jan 2023

Microbial polyphenols in Mediterranean diet improve cardiovascular health

Researchers observe a robust association between urinary phenolic metabolites, Mediterranean diet adherence, and a healthier cardiovascular status.

29 Jan 2023

Nerve stimulation therapy for spinal cord injuries shows promise in animal studies

A nerve stimulation therapy developed at Columbia University Vagelos College of Physicians and Surgeons is showing promise in animal studies and may eventually allow people with spinal cord injuries to regain function of their arms.

27 Jan 2023

Treatment to boost white blood cells may benefit patients with glioblastoma

A new study led by Washington University School of Medicine in St. Louis reveals at least one cause of low white blood cell counts in patients treated for glioblastoma and demonstrates a potential treatment strategy that improves survival in mice.

27 Jan 2023

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

A team of investigators at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has shown for the first time that a combination of targeted therapies with immunotherapy addresses one of the major reasons pancreatic cancer is so notoriously treatment resistant.

26 Jan 2023

Study identifies the DNA roots of resistance to targeted cancer therapy

A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics.

26 Jan 2023

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

A multi-institutional team led by scientists from the Medical College of Wisconsin Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who may benefit from new immunotherapies.

26 Jan 2023

Researchers receive $3.3 million NIH grant to study spectroscopic MRI for glioblastoma detection

Collaborative project with Emory University will refine groundbreaking spectroscopic MRI technology to make it easier to use.

25 Jan 2023

Ospemifene and systemic hormone therapy improve vulvovaginal atrophy symptoms, study suggests

As women age, they are more susceptible to vaginal dryness and pain during intercourse because of vulvovaginal atrophy (VVA).

25 Jan 2023

The efficacy of clarithromycin versus levofoxacin-based regimens for H.pylori treatment in naïve patients after the COVID-19 pandemic misuse of antibiotics

Researchers explored the eradication rates of Helicobacter pylori utilizing levofloxacin and clarithromycin-based regimens in patients with prior COVID-19 therapy.

25 Jan 2023

Chemotherapy schedule affects treatment outcomes in female DLBCL patients

Chemotherapy is a commonly used regimen for cancer treatment, but it is also a double-edged sword. While the drugs are highly effective at killing cancer cells, they are also notorious for killing healthy cells in the body.

24 Jan 2023

Brief exposure to diesel exhaust can affect human brain function

A new study by researchers at the University of British Columbia and the University of Victoria has shown that common levels of traffic pollution can impair human brain function in only a matter of hours.

24 Jan 2023

Clinical Trial News and Research

Integrated model helps enhance patient care for pediatric brain tumors

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

MD Anderson and Federation Bio collaborate to design and manufacture a synthetic microbial consortium

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

New technique offers a two-prong approach to attacking cancers

Researchers develop AI-based strategy for discovering high-affinity antibody drugs

New biomaterial allows for treating damaged tissue from the inside out

MINOCA: Insights into a type of heart attack that predominantly affects women

Experimental vaccine against Marburg virus shows promise in first-in-human clinical trial

Microbial polyphenols in Mediterranean diet improve cardiovascular health

Nerve stimulation therapy for spinal cord injuries shows promise in animal studies

Treatment to boost white blood cells may benefit patients with glioblastoma

Combination of targeted therapies with immunotherapy addresses treatment resistance in pancreatic cancer

Study identifies the DNA roots of resistance to targeted cancer therapy

New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

Researchers receive $3.3 million NIH grant to study spectroscopic MRI for glioblastoma detection

Ospemifene and systemic hormone therapy improve vulvovaginal atrophy symptoms, study suggests

The efficacy of clarithromycin versus levofoxacin-based regimens for H.pylori treatment in naïve patients after the COVID-19 pandemic misuse of antibiotics

Chemotherapy schedule affects treatment outcomes in female DLBCL patients

Brief exposure to diesel exhaust can affect human brain function

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