Protein C News and Research

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PFAS exposure in early life: Health risks and maternal-fetal transport mechanisms

Polyfluoroalkyl substances (PFAS) are a class of chemicals extensively used in consumer goods production due to their hydrophobic and oleophobic properties and stability.

24 Jun 2024

Tips to help keep feet healthy during summer and prevent athlete’s foot

As the days heat up and we head into the Summer, many of us suddenly seem to remember that the appendages at the end of our legs need some love and care too.

22 Jun 2024

Breakthrough in hemophilia A treatment: Sobi's ALTUVOCT receives EU marketing authorization

Sobi® today announced the European Commission has granted Marketing Authorization for ALTUVOCT™ (efanesoctocog alfa), for the treatment and prevention of bleeds and perioperative prophylaxis in hemophilia A. ALTUVOCT is a high-sustained factor VIII replacement therapy for all ages and any disease severity.

22 Jun 2024

Study uncovers new insights into the main human cold and menthol sensor TRPM8

Chronic pain affects millions worldwide, and current treatments often rely on opioids, which carry risks of addiction and overdose.

21 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

Transforming drug discovery with AI

A new AI-powered program will allow researchers to level up their drug discovery efforts.

21 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

High-resolution structures of SSTR5 reveal key interactions with neuropeptide and drug agonists

Somatostatin receptors (SSTRs) constitute a crucial family of G protein-coupled receptors (GPCRs) that play pivotal roles in regulating hormone secretion and inhibiting tumor growth.

21 Jun 2024

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Researchers identify genetic loci associated with lifetime and frequency of cannabis use.

21 Jun 2024

Using deep learning to design synthetic soluble versions of cell membrane proteins

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter cellular behavior.

21 Jun 2024

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis pathogenesis.

21 Jun 2024

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Researchers compared the effects of energy-restricted (ER) dietary patterns with nuts or without on body composition, weight, and glycemic management.

21 Jun 2024

Achieving healthy weight: The power of small changes and mindful eating

Once a person decides it's time to lose some weight, it may be difficult to determine what's the best option for them. With all the diet noise out there, what's the best way to take off those unwanted pounds - and keep them off?

20 Jun 2024

Innovative CAR T cell therapy shows promise for relapsed CIDP patients

This study is led by Professor Junnian Zheng and Ming Shi from the Cancer Institute of Xuzhou Medical University, together with the team of Professor Guiyun Cui and Wei Zhang from the Affiliated Hospital of Xuzhou Medical University.

20 Jun 2024

Moderate exercise linked to reduced burnout and higher job satisfaction among employees

Employees who exercise moderately feel less emotionally exhausted and more personally satisfied at work than their less active co-workers, a new University of Michigan study found.

20 Jun 2024

Role of SMIM1 gene in obesity uncovered

Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.

20 Jun 2024

WEHI spinout aims to revolutionize the development of cancer drugs

Australia has cemented its role in becoming a major player in the next generation of medicines with the launch of Ternarx – a globally competitive biotechnology company dedicated to finding new treatments for hard-to-treat cancers.

20 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

Unveiling the role of SOS genes in E. coli survival during antibiotic treatment

When E. coli detects damage to its genetic material, it sends out an SOS signal that alters activity inside the cells.

20 Jun 2024

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

A scientific story that began with a discovery in just one extraordinary patient is now panning out. In 2019, an international team that included researchers from two Mass General Brigham hospitals - Mass Eye and Ear and Massachusetts General Hospital (MGH) - reported on the case of a patient who did not develop cognitive impairment until her late 70s, despite being part of a family at extremely high genetic risk for developing early-onset Alzheimer's disease.

20 Jun 2024

Protein C News and Research

PFAS exposure in early life: Health risks and maternal-fetal transport mechanisms

Tips to help keep feet healthy during summer and prevent athlete’s foot

Breakthrough in hemophilia A treatment: Sobi's ALTUVOCT receives EU marketing authorization

Study uncovers new insights into the main human cold and menthol sensor TRPM8

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Transforming drug discovery with AI

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

High-resolution structures of SSTR5 reveal key interactions with neuropeptide and drug agonists

Study links lifetime cannabis use with substance use, mood disorders, celiac, and infectious diseases

Using deep learning to design synthetic soluble versions of cell membrane proteins

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Can nuts boost weight loss and blood sugar control on a calorie-restricted diet?

Achieving healthy weight: The power of small changes and mindful eating

Innovative CAR T cell therapy shows promise for relapsed CIDP patients

Moderate exercise linked to reduced burnout and higher job satisfaction among employees

Role of SMIM1 gene in obesity uncovered

WEHI spinout aims to revolutionize the development of cancer drugs

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Unveiling the role of SOS genes in E. coli survival during antibiotic treatment

One copy of the Christchurch variant may confer protection against familial Alzheimer's disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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