Therapeutics News and Research

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Novel strategy can shrink tumors and prolong survival in mice

A research team based at the University of Ottawa and The Ottawa Hospital has developed a virus that infects and kills cancer cells without harming normal cells, while also sending out signals to prepare nearby uninfected cancer cells for viral attack.

11 Apr 2022

Vaccines safely protect IBD patients from COVID-19

COVID-19 vaccines taken by people with inflammatory bowel disease (IBD), which affects millions worldwide, safely and effectively protects them from the SARS-Cov-2 virus, a Rutgers study finds.

11 Apr 2022

What does the Future of Microfluidics within Research Look Like?

We speak to France Hamber, CEO of Fluigent, about their microfluidics solutions and how they are allowing scientists to focus more on the science than the setup.

From Fluigent 11 Apr 2022

Let’s Talk about Parkinson’s

In recognition of World Parkinson's Day, we speak to Dr. Arthur Roach, Director of Research at Parkinson’s UK, about the current Parkinson's landscape.

11 Apr 2022

Study: Less than half of clinical trials report race/ethnicity data

Clinical trials represent one the largest investments of collective resources in science. These studies, which recruit participants and rigorously evaluate new interventions and therapeutics, aim to advance scientific knowledge and improve patient treatment.

11 Apr 2022

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

In a recent article published in the journal Proceedings of the National Academy of Sciences (PNAS), researchers reviewed the present-day therapeutic landscape of coronavirus disease 2019 (COVID-19) and addressed future opportunities to overcome challenges that hinder drug development and improve the global preparedness for future pandemics.

10 Apr 2022

The effect of unsuppressed HIV on T-cell response to COVID-19

A new study evaluates the impact of HIV infection on SARS-CoV-2 T-cell responses during the first and second waves of COVID-19 in South Africa.

10 Apr 2022

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

Natural killer (NK) cells derived from cord blood that were activated and complexed with a CD30/CD16A bispecific antibody elicited an 89 percent overall response rate in patients with relapsed or refractory CD30+ lymphoma, according to results from a phase I/II clinical trial presented at the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Patients with non-small cell lung cancer (NSCLC) treated with the KRAS G12C inhibitor sotorasib (Lumakras) had a two-year overall survival rate of 32.5 percent, according to data from the CodeBreaK 100 clinical trial presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Modified version of hormone kisspeptin can be used to treat non-alcoholic fatty liver disease

A hormone that triggers puberty and controls fertility in humans might be developed as a treatment for non-alcoholic fatty liver disease, according to new Rutgers research.

7 Apr 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

A recent study analyzed the antibody that mediated the COVID-19 vaccine-induced thrombotic thrombocytopenia.

7 Apr 2022

Patient outcomes after influenza, RSV, or SARS-CoV-2 hospitalization

A recent study posted to the medRxiv* preprint server investigated the elements that predicted all-cause mortality among individuals hospitalized due to influenza, respiratory syncytial virus (RSV), or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

7 Apr 2022

COVID boosters protect you better than monoclonal antibodies, or natural infection

In a new study published in the journal Science Translational Medicine, researchers analyzed the neutralization of the Omicron BA.1 variant pseudovirus by post-vaccination serum samples.

6 Apr 2022

Study shows link between language status and health outcomes during COVID-19 hospitalizations

The language status of patients hospitalized for COVID-19 may significantly impact health outcomes during their admission, as non-English speaking individuals were found to have 35 percent greater odds of dying or requiring intensive care unit (ICU) support during the earliest phase of the pandemic compared to English-speaking patients, according to a study by Mass General Brigham (MGB).

6 Apr 2022

Therapeutics News and Research

Novel strategy can shrink tumors and prolong survival in mice

Vaccines safely protect IBD patients from COVID-19

What does the Future of Microfluidics within Research Look Like?

Let’s Talk about Parkinson’s

Study: Less than half of clinical trials report race/ethnicity data

Challenges, unmet needs and future opportunities in COVID-19 therapeutics

The effect of unsuppressed HIV on T-cell response to COVID-19

NK cells complexed with bispecific antibody elicit high response rate in patients with resistant lymphomas

NSCLC patients treated with KRAS G12C inhibitor sotorasib may receive long-term clinical benefit

Modified version of hormone kisspeptin can be used to treat non-alcoholic fatty liver disease

Researchers design RNA molecules for delivering therapies directly to beta cells

Molecular signature of highly stereotyped clonotypic anti-PF4 antibodies indicates shared pathways of antibody production in VITT patients

Patient outcomes after influenza, RSV, or SARS-CoV-2 hospitalization

COVID boosters protect you better than monoclonal antibodies, or natural infection

Study shows link between language status and health outcomes during COVID-19 hospitalizations

Virtual reality psychological therapy shown to work well for patients with mental health problems

New technique can reliably identify patients most likely to suffer post-surgery pain

New tissue engineered neuromuscular interfaces “babysit” the muscles to improve functional recovery

SARS-CoV-2 ORF8 interferes with antibody-dependent cellular cytotoxicity

Gut bacterium may be an important factor in resistance to antihypertensive medications

Next-generation therapeutics eBook eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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