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Researchers develop a 3D-bioprinted in vitro model of stenotic brain blood vessels

Cerebrovascular diseases such as atherosclerosis and stroke remain a major cause of morbidity and mortality worldwide.

19 Aug 2025

Aging weakens blood-brain barrier and impairs memory

A new study from researchers at the University of Illinois Chicago reveals how the blood-brain barrier gets leakier with age, contributing to memory deficits.

12 Aug 2025

Exercise targets specific brain cells to protect against Alzheimer’s

Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer's disease, researchers from Mass General Brigham and collaborators at SUNY Upstate Medical University have identified specific brain cell types that responded most to exercise.

12 Jun 2025

Study delves into the role of SOX9 in hypospadias development

Hypospadias is a widespread congenital disorder, characterized by an abnormal placement of the urethral opening, impacting as many as 3.42% of male children worldwide. Beyond the physical consequences, this condition can lead to psychological and fertility issues.

10 Mar 2025

New study reveals how anticancer drugs enter cancer cells

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell.

5 Feb 2025

Research identifies key factors in initiating tumor dormancy

A new research paper was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Initiation of tumor dormancy by the lymphovascular embolus."

30 Oct 2024

Study reveals how morphogens and cell adhesion create sharp tissue boundaries

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

8 Oct 2024

Scientists uncover role of Wnt in kidney formation

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its complex roles in development and disease.

1 Oct 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Cell adhesion and starvation found to be key drivers of pattern formation in keratinocytes

Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion, Hokkaido University researchers find.

12 Aug 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Wound warriors: How microbes influence healing and infection risks

Study explores how wound microbiota affect skin repair and infection risk by altering host immune responses, underscoring the complexity of microbial interactions in wound healing.

7 Apr 2024

Biomechanical model simulates breast tumor growth

Scientists from Universidad Carlos III de Madrid (UC3M) and Johns Hopkins University (JHU), in the USA, have analyzed the growth of breast tumors from a biomechanical perspective and have created a computational model that simulates the invasion process of cancer cells, depending on the characteristics of the surrounding tissue and cell junctions, among other parameters.

21 Mar 2024