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A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Researchers uncover how a gene influences cell size across various cell types

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis behind cell size has largely been a mystery.

17 Dec 2025

Researchers identify key differences between two subtypes of chronic lymphocytic leukemia

Researchers at the University of Eastern Finland and their international collaborators have identified key developmental and molecular differences between the two main subtypes of chronic lymphocytic leukemia, CLL.

18 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Daily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health.

21 Oct 2025

MRI age clocks reveal how each organ ages differently and predict who develops disease or lives longer

Researchers developed seven MRI-based biological age clocks across major organs using UK Biobank imaging, linking each to proteins, metabolites, genetics, disease risks, mortality, and cognitive decline. These organ-specific age gaps reveal how uneven aging shapes vulnerability to conditions such as diabetes, hypertension, and dementia, opening new paths for precision prevention and clinical trial stratification

19 Oct 2025

Genetic study reveals links between cannabis use and mental health

University of California San Diego of Medicine researchers, in collaboration with the genetic testing company 23andMe, have identified regions of the human genome associated with cannabis use, uncovering new relationships with psychiatric, cognitive and physical health.

13 Oct 2025

Johns Hopkins team develops urine-based test for prostate cancer detection

Researchers at the Johns Hopkins Kimmel Cancer Center, Johns Hopkins All Children's Hospital and four other institutions have devised a novel method to test for prostate cancer using biomarkers present in urine, funded in part by the National Institutes of Health.

9 Sep 2025

Urine test identifies three biomarkers for accurate prostate cancer detection

2 Sep 2025

Fucosylation emerges as a key player in digestive inflammatory diseases and cancers

Fucosylation, a crucial post-translational modification, has emerged as a significant factor influencing digestive inflammatory diseases and cancers.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Respiratory viruses such as influenza and COVID-19 can reactivate dormant breast cancer cells in the lungs, raising the risk of metastasis. The process is driven by IL-6–induced cell changes and immune suppression, with the highest recurrence risk soon after infection.

14 Aug 2025

Genetic markers could help prevent age-related frailty

Novel genetic insights into frailty highlight potential early predictors, aiding in the prevention of age-related decline and improving health outcomes.

7 Aug 2025

Innovative implant material combines bone regeneration and infection control

A research team from Shanghai Jiao Tong University has resulted in a significant advancement in the field of orthopedic implant materials.

6 Aug 2025

Microcone-enhanced microfluidic device captures circulating tumor cells efficiently

Circulating tumor cells (CTCs) refer to cancer cells that have broken off from a primary tumor. These tumor cells can travel through the blood in the circulatory system and lodge themselves in other organs to cause secondary tumors.

29 Jul 2025

New autoimmune target identified in pediatric idiopathic nephrotic syndrome

Idiopathic nephrotic syndrome (INS) is a serious kidney disease in children with no clear cause. In a recent study, researchers have identified a novel autoantibody targeting vinculin—a protein crucial for kidney cell structure—as a significant factor in INS.

14 Jul 2025