Crohn’s Disease News and Research

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Researchers discover why smoking tobacco helps people with ulcerative colitis

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine.

25 Aug 2025

Compound-level diet analysis sheds light on hidden triggers in IBD

Dutch researchers identified specific food compounds that influence remission and flare risk in patients with inflammatory bowel disease. The study shows compound-level dietary analysis could help personalize IBD management and clarify conflicting advice about diet.

18 Jun 2025

Genetic mutation tied to Crohn's disease can worsen iron deficiency and anemia

A study led by biomedical scientists at the University of California, Riverside School of Medicine shows how a genetic mutation associated with Crohn's disease can worsen iron deficiency and anemia - one of the most common complications experienced by patients with inflammatory bowel disease, or IBD.

6 Jun 2025

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

A global meta-analysis found that people with ADHD are significantly more likely to have irritable bowel syndrome (IBS), while the overall risk for other intestinal disorders is not increased. The findings highlight the importance of gut-brain interactions in ADHD and call for further research on microbiome-based therapies.

3 Jun 2025

Scientists build world's most accessible gut bacteria collection to unlock health and disease clues

Researchers have developed the Human Intestinal Bacteria Collection (HiBC), comprising 340 gut bacterial strains from 198 species, including 29 newly described taxa, made publicly available for functional microbiome research.

7 May 2025

Ultra-processed foods linked to higher psoriasis risk

A large UK Biobank study found that higher consumption of ultra-processed foods (UPFs) is associated with an increased risk of developing psoriasis. Each 10% increase in UPF intake raised psoriasis risk by 6%, with obesity and inflammation partially mediating this effect.

4 May 2025

GLP-1 agonists may reshape the gut microbiome

Research reveals GLP-1 receptor agonists influence gut microbiome, enhancing metabolic health and offering anti-inflammatory benefits for diabetes management.

11 Apr 2025

Mount Sinai-led research uncovers mechanisms behind Crohn's disease inflammation

A research team led by Mount Sinai has uncovered mechanisms of abnormal immune cell function that may lead to Crohn's disease, according to findings published in Science Immunology on March 21.

22 Mar 2025

Plant-based diets and IBD

This study highlights the link between plant-based diets and reduced IBD risk, suggesting dietary choices play a crucial role in managing chronic inflammation.

19 Mar 2025

Study shows how autism-linked picky eating causes serious vitamin deficiencies

Children with autism spectrum disorder (ASD) face a high risk of multiple micronutrient deficiencies, especially vitamins A, D, B12, and calcium, due to extreme food selectivity. These deficiencies can lead to severe health issues like rickets, vision loss, and immune dysfunction, even in children with normal body weight.

13 Mar 2025

Eating ultra-processed foods harms your gut—here’s how inflammation takes hold

Ultra-processed foods disrupt gut microbiome balance, causing inflammation, reduced microbial diversity, and increased gut permeability. This microbiome imbalance contributes to chronic diseases including diabetes, IBD, cancer, and neurological disorders.

6 Mar 2025

Study finds potential biomarker for joint inflammation in Crohn's disease

People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential biomarker, according to new study by Weill Cornell Medicine researchers.

5 Mar 2025

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Crohn's disease, a debilitating inflammatory bowel disease, has many known contributing factors, including bacterial changes in the microbiome that foster an inflammatory environment.

3 Mar 2025

Integrating video capsule endoscopy technology in probiotic research

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

Strengthening the gut barrier may halt Crohn’s disease progression

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease.

18 Feb 2025

Study explores microbiome reboot to prolong effect of Crohn's disease therapy

A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid foods. However, the exact reasons why this is helpful were previously unclear.

11 Feb 2025