Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

Study creates genetic roadmap of how HIV virus interacts with human cells

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

20 Apr 2026

Antiretroviral therapy reduces biological aging in people living with HIV

A major study presented today at ESCMID Global 2026 has found that antiretroviral therapy (ART) reduces accelerated biological ageing in people with HIV (PWH) by nearly four years, a finding that could transform how clinicians monitor HIV treatment and long-term health outcomes.

20 Apr 2026

Requests for “unvaccinated” blood lead to delays and patient harm

The trend for unvaccinated blood donations raises concerns about patient safety and resource efficiency, emphasizing the need for better transfusion protocols.

6 Apr 2026

Study reveals immune changes in HIV and HCV coinfected patients

Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection leads to severe systemic inflammation, increasing non-AIDS morbidity and mortality risk. CD39 ectoenzyme on T-cells, which catalyzes the conversion of pro-inflammatory purines to immunosuppressive adenosine, plays an important role in inflammation control.

28 Mar 2026

FDA approves first gene therapy for rare pediatric immune disorder

Dr. Donald Kohn has been developing gene therapies for rare pediatric immune disorders for over 30 years.

27 Mar 2026

Researchers explore "block and lock" strategy for functional HIV cure

For millions of people living with HIV, a daily regimen of medications is a lifelong necessity. If they stop taking the drugs-commonly referred to as antiretroviral therapy-the virus usually rushes back within weeks.

23 Mar 2026

Exercise cuts 'chemo brain' and fatigue in cancer patients

Implementing a simple exercise plan during chemotherapy may ease cognitive impairment and fatigue, promoting better health outcomes for cancer patients.

17 Mar 2026

Circular RNA produced by HIV boosts viral replication

For decades scientists have recognized that human immunodeficiency virus (HIV) is a formidable viral pathogen.

13 Mar 2026

Spatial intelligence platform supports health policy decisions aimed at ending HIV

INCLIVA Healthcare Research Institute-University Clinical Hospital of Valencia, the Universitat Politècnica de València - through its VRAIN Institute, the Valencia Anti-AIDS Committee and the Centre for Epidemiological Studies on Sexually Transmitted Infections and AIDS in Catalonia (CEEISCAT) have joined forces to develop a spatial intelligence platform to support health policy decisions aimed at optimizing the prevention of human immunodeficiency virus (HIV) and accelerating its early diagnosis.

5 Mar 2026

New HIV-seq tool advances understanding of persistent viral reservoirs

For people living with human immunodeficiency virus (HIV), life-saving antiretroviral therapy keeps their HIV-infected immune cells from making new copies of the virus, preventing illness and transmission.

3 Mar 2026

Obesity sharply increases hospitalisation risk from infections, global analysis shows

Adult obesity is associated with a substantially higher risk of severe hospital-treated or fatal infections across multiple pathogens, with risk increasing as obesity severity rises. Global modelling suggests roughly one in ten infection-related deaths worldwide may be attributable to adult obesity, although causality cannot be confirmed.

15 Feb 2026

A pill that confirms you actually swallowed your medicine

SAFARI capsule technology offers a novel solution for medication adherence, using a dissolvable Faraday cage to verify ingestion without batteries or waste.

12 Jan 2026

New federal guidelines shift cervical cancer screening to HPV testing

New cervical cancer screening guidelines emphasize self-collection and hrHPV testing, aiming to increase screening rates and improve women's health outcomes.

8 Jan 2026

To knock down health-system hurdles between you and HIV prevention, try these 6 things

A couple of years ago, Matthew Hurley got the kind of text people fear.

5 Jan 2026

Online reference library provides a more accurate picture of drug exposure

Doctors and researchers try to understand what medications a person has taken by asking patients directly or by looking at medical records. But this information is often incomplete.

9 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

New AI investment aims to accelerate the search for an effective HIV vaccine

As of 2024, over 40 million people in the world are diagnosed with human immunodeficiency virus (HIV)-a chronic, life-threatening infection that remains one of the leading global causes of death.

18 Nov 2025

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Fondazione Telethon announces the positive opinion issued by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending marketing authorization in the European Union for Waskyra, an ex vivo gene therapy for Wiskott-Aldrich Syndrome (WAS), a rare and life-threatening primary immunodeficiency.

14 Nov 2025

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients through a collaboration with Boston Children's Hospital.

7 Nov 2025

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025