Interferon gamma News and Research

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Injectable scaffold vaccine shows strong protection against implant-related MRSA

Research reveals that silica scaffolds can train the immune system against S. aureus, offering a novel approach to prevent orthopedic device infections.

4 Dec 2025

Lack of dietary iron weakens immune response in the lungs

Researchers at Columbia University have found that a lack of dietary iron early in life can prevent immune cells in the lung from making a key protein that helps fight viral infections, even after iron levels are restored.

2 Dec 2025

Regenerative medicine offers a pathway toward curing type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells.

26 Nov 2025

Marine bacterium shows powerful therapeutic effects against colorectal cancer

A research team led by Professor Eijiro Miyako at the Graduate School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology (JAIST), has discovered that the marine bacterium Photobacterium angustum demonstrates remarkable therapeutic efficacy against colorectal cancer.

21 Nov 2025

Multimodal nanocarriers offer targeted solutions for tumor treatment

Cancer remains a leading cause of global morbidity and mortality. Traditional therapies like chemotherapy and radiotherapy are often limited by their lack of specificity, leading to systemic toxicity and the emergence of drug resistance.

10 Oct 2025

Decoding the signaling networks and metabolic dysregulation underlying sepsis

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction.

10 Oct 2025

Virtual memory T cells provide nonspecific immunity for infants early in life

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.

31 Jul 2025

Nasal antibody spray shields mice from pollen-triggered allergies and asthma

Intranasal delivery of a monoclonal IgG1 antibody targeting mugwort pollen protected mice from allergic rhinitis and asthma symptoms, without lowering systemic IgE levels. This localized, non-invasive approach dampened Th2 inflammation and preserved healthy airway tissue in sensitized mice.

14 Jul 2025

UCLA researchers discover new way to prevent immunotherapy-induced type 1 diabetes

A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, a rare but life-threatening side effect of cancer immunotherapy, using an existing class of autoimmune drugs.

8 Jul 2025

Beetle-inspired tuberculosis testing device offers accurate detection for people with HIV

Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB from traditional tests by eliminating the immune cells relied upon to sound the alarm.

27 Jun 2025

Key proteins and pathways drive the success of CAR-T cell therapy

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways involved in the efficacy of immunotherapy based on CAR-T cells (lymphocytes modified in the laboratory to fight cancer).

4 Jun 2025

Neutrophil subpopulations could help predict autoimmune disease relapse

Neutrophils, one of the immune system warriors that were thought to be all the same, turn out to be diverse. Unfortunately, these cells are also active in autoimmune diseases.

24 Apr 2025

New strategy for TB screening aims to save lives

A new strategy for tuberculosis (TB) screening, proposed by a team of researchers led by Queen Mary University of London, provides a solution to problems with current TB screening, which does not always accurately detect disease.

24 Apr 2025

Exploring the complex association between anemia and retinopathy of prematurity

Anemia is a common condition in premature infants, particularly those at risk for retinopathy of prematurity (ROP).

10 Apr 2025

Research uncovers root cause of gland damage in Sjögren's syndrome

Sjögren's syndrome is a chronic autoimmune disorder that affects millions worldwide, especially women, causing unrelenting dryness of the mouth and eyes.

7 Apr 2025

Targeted inhibition of a 'signal jammer' protein may improve tumor response to immunotherapy

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein voltage-dependent anion channel 2 (VDAC2) like a signal jammer to prevent the body's anticancer systems from communicating with the immune system.

19 Mar 2025

Interferon gamma persistence offers clues to Long COVID and potential therapies

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

22 Feb 2025

Sweat fails to match blood in tracking inflammation after heart attacks

Researchers found that while sweat biomarkers remain stable, plasma biomarkers show significant inflammatory changes after a heart attack, highlighting the limitations of sweat analysis for tracking recovery.

17 Feb 2025

New insight into gut stem cell aging

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling is essential for preserving the intestinal stem cell population during aging.

13 Feb 2025

Gut microbes influence how well cancer patients respond to immunotherapy

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

11 Feb 2025