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Cigarette smoke extract primes airway cells for greater nanoplastic damage

Researchers found that cigarette smoke extract weakened epithelial barriers and increased the proportion of human airway cells that were polystyrene nanoparticle-positive. Sequential treatment caused greater metabolic disruption and increased mucus-producing cells, suggesting heightened epithelial vulnerability, although the findings are limited to in vitro models.

30 Jul 2026

Study reveals how gum disease drives systemic inflammation

A recent study revealed that periodontitis reprograms bone marrow neutrophils through a Chac2-driven glutathione metabolic pathway, promoting a highly inflammatory N1 state that fuels systemic inflammation.

28 Jul 2026

Study identifies simvastatin as promising adjuvant for periodontitis treatment

Porphyromonas gingivalis can evade antibiotics by invading host cells, contributing to recurrent periodontitis and persistent tissue damage.

26 Jul 2026

Researchers uncover molecular switch controlling nutrient-driven cell growth

Cells carry their own growth switches. When enough nutrients-amino acids in particular-are available, cells flip this switch on and begin to grow. Researchers at KAIST and Yonsei University have now uncovered the molecular mechanism by which amino acid signals activate this cellular growth switch.

26 Jul 2026

Emerging non-endocytic transmembrane delivery strategies for precision medicine

Conventional endocytosis-mediated delivery is limited by poor endosomal escape efficiency, making intracellular delivery of therapeutic biomacromolecules a long-standing challenge in modern biomedical research.

24 Jul 2026

Scientists create programmable immune receptors for disease-resistant crops

Crop production faces threats from plant pathogens. Traditional disease-resistance breeding relies heavily on natural plant resistance genes that encode immune receptors adapted to particular pathogens.

23 Jul 2026

Computationally designed antibody attacks previously untreatable KRAS cancer mutations

Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them.

23 Jul 2026

Review expands the role of selenium metabolism in ferroptosis

For decades, selenium has been recognized as an essential micronutrient, and glutathione peroxidase 4 (GPX4)-a selenium-containing enzyme-has been widely regarded as the central guardian against ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation.

23 Jul 2026

Occult hepatitis B mutations drive liver cancer growth via Akt mTOR pathway

Occult hepatitis B virus (OBI) infection presents a significant global health challenge, notoriously flying under the radar of standard viral screening while relentlessly driving the pathogenesis of hepatocellular carcinoma (HCC).

22 Jul 2026

Study reveals mechanism underlying HBV-induced liver inflammation

Chronic hepatitis B virus (HBV) infection remains a major cause of global liver morbidity, leading to progressive necroinflammation that often culminates in cirrhosis and hepatocellular carcinoma.

17 Jul 2026

New drug candidate improves Parkinson's treatment in animal models

For many people with Parkinson's disease, the body stops moving the way it used to. A hand may tremble at rest. Muscles may stiffen.

15 Jul 2026

Study uncovers mechanism that regulates how the body uses stored fat to produce energy

An international study by scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the University of California, Los Angeles (UCLA) has identified a fundamental mechanism that regulates how the body uses stored fat to produce energy.

9 Jul 2026

Adaptor proteins regulate macrophage behavior to control cancer growth

A new review was published in Volume 13 of Oncoscience on May 22, 2026, titled "Adaptor proteins regulating tumor-associated macrophage polarization during cancer progression."

7 Jul 2026

Neutral lipids may act as functional medium for controlling supramolecular polymerization

The formation of supramolecular polymers within living cells is an emerging strategy for regulating cellular functions, and lipid droplets (LDs) are promising environments for such processes.

6 Jul 2026

New discovery sheds light on how the human body controls Salmonella infections

Salmonella, an infection that causes diarrhea, fever, and abdominal pain, is the most common form of bacterial food poisoning in the U.S., sickening more than a million people each year.

26 Jun 2026

Cone opsin structures offer insights into vision loss

The retina of the human eye contains six to seven million cone cells. These cells contain light-sensitive proteins known as cone opsins.

25 Jun 2026

Lactate and lactylation play multifaceted roles in pancreatic ductal adenocarcinoma

A comprehensive review recently published in Current Molecular Pharmacology illuminates the pivotal, multifaceted roles of lactate and its downstream protein modification, lactylation, in pancreatic ductal adenocarcinoma (PDAC).

25 Jun 2026

Gene linked to lower BMI points researchers toward a new obesity target

A review in Cardiology in Review highlights GPR75, a receptor for 20-HETE, as a promising therapeutic target for obesity and metabolic syndrome. Evidence from genetic studies, cell experiments, and mouse models suggests that blocking this pathway could influence weight gain, insulin resistance, hypertension, inflammation, and vascular dysfunction.

25 Jun 2026

Aging immune cells may explain why autoimmunity rises later in life

A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

21 Jun 2026

Study discovers epigenetic mechanism protecting tooth progenitor cells from stress

An epigenetic "mechanostat" has been discovered that protects tooth-forming progenitor cells from mechanical stress and supports lifelong tissue renewal.

19 Jun 2026