Joint Pain News and Research

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Long COVID symptom clusters that could reshape patient care

A systematic review of Long COVID identifies symptom clusters, highlighting fatigue and proposing a management framework for personalized treatment strategies.

12 Jan 2026

Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving treatment adherence in the PIONEER trial.

7 Jan 2026

Genes and biological networks that drive long COVID risk

This study merges causal genetics and network theory, revealing 32 genes linked to long COVID, offering insights for diagnostics and personalized therapies.

19 Dec 2025

Half of hospitalized COVID-19 patients developed long COVID

Research from Thailand shows high long COVID prevalence in hospitalized patients, with severe illness increasing risk and vaccination offering protection.

15 Dec 2025

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

UCI Health launches clinical trial to test investigational cell therapy for lupus

UCI Health has opened a clinical trial to test an investigational cell therapy for lupus with the potential to give patients long-term remission of symptoms.

17 Nov 2025

EULAR develops first classification criteria for hemochromatosis arthropathy

EULAR - The European Alliance of Associations for Rheumatology - has developed the first classification criteria for hemochromatosis arthropathy (HA) from a unique derivation cohort using rigorous methodology.

5 Nov 2025

Study highlights high prevalence of non-coeliac gluten sensitivity lacking clear markers

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either coeliac disease or wheat allergy, finds a large systematic review and meta-analysis published online in Gut.

29 Oct 2025

Understanding the impact of chikungunya on children

Chikungunya is a vector-borne disease that affects both adults and children. While global efforts are ongoing to tackle chikungunya in adults, progress in addressing pediatric chikungunya remains inadequate.

10 Oct 2025

Hormone replacement therapy may reverse menopause-related immune changes

A study led by researchers at Queen Mary University of London has found that hormone replacement therapy (HRT) may help reverse changes in the immune system caused by menopause, potentially booting immune health.

9 Oct 2025

Thousands of ‘healthy’ Brits are unknowingly low on iron

A study reveals 6% of health-conscious UK adults have anemia, primarily due to iron deficiency, often without noticeable symptoms, especially in women.

9 Oct 2025

Milken Institute and Ann Theodore Foundation award over $2.5 million for sarcoidosis research

The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in partnership with the Ann Theodore Foundation (ATF), today announced that the Ann Theodore Foundation Breakthrough Sarcoidosis Initiative (ATF-BSI) has awarded five grants totaling more than $2.5 million to interdisciplinary research teams.

6 Oct 2025

Large-scale analysis offers insights into sporadic nature of chikungunya virus outbreaks

The symptoms come on quickly - acute fever, followed by debilitating joint pain that can last for months. Though rarely fatal, the chikungunya virus, a mosquito-borne illness, can be particularly severe for high-risk individuals, including newborns and older adults.

6 Oct 2025

Randomized trial shows exercise benefits for post-COVID immune regulation

Exercise can help to restore a more normal, well-regulated immune system in people with post-COVID syndrome, according to a gold-standard randomised-controlled trial presented at the European Respiratory Society Congress in Amsterdam, the Netherlands.

30 Sep 2025

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

A single course of low-dose radiation therapy may provide a safe and effective alternative treatment option for people with painful knee osteoarthritis according to a new randomized, placebo-controlled clinical trial.

29 Sep 2025

Survey shows low public concern despite rising West Nile virus infections in the U.S.

West Nile virus is the leading cause of mosquito-borne illness in the continental United States. As of Sept. 23, over 1,100 human cases of West Nile disease have been reported across 42 states, according to the U.S. Centers for Disease Control and Prevention (CDC), including nearly 750 cases of the more serious neuroinvasive form which affects the brain.

26 Sep 2025

GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide.

16 Sep 2025

Early B cell response prevents Oropouche virus from reaching the brain

Research conducted on mice has identified that the rapid response of a specific type of defense cell is essential for controlling Oropouche virus infections and preventing serious neurological damage.

14 Sep 2025

How a Réunion Island outbreak sparked France’s record chikungunya season

Mainland France recorded its earliest-ever local chikungunya outbreaks in May 2025, with 10 clusters (27 cases) across five regions, driven by travelers importing the virus from Réunion Island. The surge highlights growing vulnerability to mosquito-borne diseases in Europe as Aedes albopictus expands northward.

18 Aug 2025