Joint Pain News and Research

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Study reveals new immune mechanism behind mevalonate kinase deficiency

Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder.

30 Apr 2026

Study links ultra-processed food intake to poorer thigh muscle quality

A Radiology study of 615 adults at risk for knee osteoarthritis found that higher ultra-processed food intake was associated with greater fat infiltration in thigh muscles on MRI, a marker of poorer muscle quality. The association remained after adjustment for BMI, was stronger in models using abdominal circumference, and did not differ significantly by sex.

15 Apr 2026

Testosterone level is not always the key to male wellbeing

The connection between testosterone and well-being is weaker than many people think. Although there are clear health connections, a higher testosterone level is not always the key to well-being, according to a thesis at the University of Gothenburg.

31 Mar 2026

Post amputation pain differs with movement and prosthetic type

Researchers at the University of Colorado Anschutz have identified a critical gap in how post-amputation pain is evaluated and treated.

6 Mar 2026

He needs an expensive drug. A copay card helped — until it didn’t.

Over the course of 2025, Jayant Mishra of Mission Viejo, California, progressively developed scaly, itchy red patches on his skin. Then came the pain and swelling in the joints of his hands, making it difficult to do his work at a bank.

27 Feb 2026

Griffith researchers on the cusp of new vaccine to prevent chikungunya

Griffith University researchers are on the cusp of a new vaccine to prevent chikungunya, a global health threat which attacks human joint tissue.

6 Feb 2026

Daily physical activities provide greater benefits for osteoarthritis patients than handgrip strength

Daily physical activities play a far greater role in the well-being of patients with osteoarthritis than handgrip strength or isolated motor tasks, according to new research from the University of Sharjah.

2 Feb 2026

Urate-lowering gout treatment can reduce the risk of heart attack and stroke

A groundbreaking new study, led by experts at the University of Nottingham, has found that medicines used to treat gout can also reduce the risk of heart attack and stroke in people with gout.

27 Jan 2026

Early treatment delays rheumatoid arthritis onset in high-risk individuals

Treating people who are at high risk of rheumatoid arthritis (RA) can delay the onset of the disease for several years, with benefits also continuing well after treatment has stopped.

20 Jan 2026

Long COVID symptom clusters that could reshape patient care

A systematic review of Long COVID identifies symptom clusters, highlighting fatigue and proposing a management framework for personalized treatment strategies.

12 Jan 2026

Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer

Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving treatment adherence in the PIONEER trial.

7 Jan 2026

Genes and biological networks that drive long COVID risk

This study merges causal genetics and network theory, revealing 32 genes linked to long COVID, offering insights for diagnostics and personalized therapies.

19 Dec 2025

Half of hospitalized COVID-19 patients developed long COVID

Research from Thailand shows high long COVID prevalence in hospitalized patients, with severe illness increasing risk and vaccination offering protection.

15 Dec 2025

SN101 iPSC-derived therapy relieves chronic pain and preserves joints

SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach to chronic pain management and joint tissue preservation.

12 Dec 2025

Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

UCI Health launches clinical trial to test investigational cell therapy for lupus

UCI Health has opened a clinical trial to test an investigational cell therapy for lupus with the potential to give patients long-term remission of symptoms.

17 Nov 2025

EULAR develops first classification criteria for hemochromatosis arthropathy

EULAR - The European Alliance of Associations for Rheumatology - has developed the first classification criteria for hemochromatosis arthropathy (HA) from a unique derivation cohort using rigorous methodology.

5 Nov 2025

Study highlights high prevalence of non-coeliac gluten sensitivity lacking clear markers

Around one in ten people worldwide report gastrointestinal and other symptoms such as fatigue and headache after eating foods containing gluten or wheat despite not having a diagnosis of either coeliac disease or wheat allergy, finds a large systematic review and meta-analysis published online in Gut.

29 Oct 2025

Understanding the impact of chikungunya on children

Chikungunya is a vector-borne disease that affects both adults and children. While global efforts are ongoing to tackle chikungunya in adults, progress in addressing pediatric chikungunya remains inadequate.

10 Oct 2025

Hormone replacement therapy may reverse menopause-related immune changes

A study led by researchers at Queen Mary University of London has found that hormone replacement therapy (HRT) may help reverse changes in the immune system caused by menopause, potentially booting immune health.

9 Oct 2025