Lymphadenopathy News and Research

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Lymphadenopathy refers to the enlargement of one or more lymph nodes, the bean-shaped glands found in the neck, armpits, chest, groin, and abdomen. Lymphadenopathy may occur in just one part of the body, in which case it is referred to as “localized” or it may be present in two or more body areas, in which case it is referred to as “generalized.” The condition most commonly affects nodes in the neck (cervical lymph nodes).

The effectiveness of respiratory interventions and case isolation measures in reducing or preventing the transmission of mpox in humans

Researchers conducted a systematic review to evaluate the effectiveness of case isolation and respiratory interventions in limiting the transmission of mpox in humans.

20 Feb 2023

A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

Study demonstrates intrahost MPXV variation within a single lesion

Researchers reported on the clinical and molecular characteristics of MPXV infections in Finland.

31 Jan 2023

Underlying genetic cause for MIS-C complications after COVID-19 identified

A recent Science journal study determined the underlying cause of MIS-C related to SARS-CoV-2 in some children. It hypothesized that monogenic inborn errors of immunity (IEI) is the primary reason for this condition. Identifying these inborn errors is expected to help elucidate the disease's cellular, molecular, and immunological basis.

2 Jan 2023

What are the characteristics of misdiagnosed human mpox cases?

In a recent study, researchers characterized overlooked cases of monkeypox (MPX).

21 Dec 2022

The mpox viral load kinetics over time in various parts of the body

Researchers characterized the time to mpox virus clearance of immunocompetent individuals with mild MPX in a real-world community-based setting utilizing longitudinal information.

16 Dec 2022

Study concludes monkeypox virus is readily detected by qPCR using three clinically validated assays

Researchers validated monkeypox virus (MPXV) quantitative polymerase chain reaction (qPCR) assays.

17 Nov 2022

What are the eye complications associated with monkeypox infection?

A new study describes the association between monkeypox infection and eye complications in humans.

9 Nov 2022

Monkeypox: Painful, itchy skin lesions localized in the genital region

In the setting of the current monkeypox outbreak it is important to consider different clinical courses. This includes skin changes/lesions that are primarily localized at the presumed inoculation sites, a low exanthematous component, and onset of general symptoms only over the course if the illness.

4 Nov 2022

Study explores the stability of monkeypox viral DNA in various body fluid samples

Researchers used laboratory diagnostic testing data of monkeypox cases and performed. They performed mathematical modeling to predict how long monkeypox viral deoxyribonucleic acid (DNA) remains detectable in different body fluid samples.

24 Oct 2022

Review of characteristics of human monkeypox

Researchers conducted a scoping review of available literature on monkeypox (MPX), in a new study.

20 Oct 2022

Bioinformatics analysis of monkeypox virus-host cell interactions

A recent study posted to the bioRxiv* preprint server reported the interaction between monkeypox and human cells. Molecular sequences were screened to identify differentially expressed genes (DEGs) and their associated signal pathway, expression regulation, and metabolic pathways.

18 Oct 2022

What is the impact of monkeypox infection on the hemostatic system?

In a recent study, researchers determined if monkeypox (MPX) infection affected the hemostatic system like that observed in coronavirus disease 2019 (COVID-19).

6 Oct 2022

Myocarditis may be attributable to monkeypox infection

A new study published in Emerging Infectious Diseases found that myocardial infiltration could cause myocarditis during monkeypox virus infection.

5 Oct 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

How smallpox and monkeypox viruses affect the nervous system

A recent study provides an overview of existing literature on the complications of infection with both smallpox and monkeypox virus.

25 Sep 2022

An unusual case of Monkeypox virus transmission by needlestick injury

In a recent study published in the U.S. Centers for Disease Control and Prevention journal Emerging Infectious Diseases, researchers described an unusual case of patient-to-healthcare worker (HCW) monkeypox virus (MPXV) transmission via a needlestick injury that occured in Brazil.

21 Sep 2022