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Scientists find links between bipolar disorder and rare loss-of-function variants in two genes

Scientists at deCODE genetics, a subsidiary of Amgen, reveal today in Nature Genetics associations between bipolar disorder and rare loss-of-function variants in two genes.

25 Mar 2025

Study uncovers a significant presence of manic symptoms in schizophrenia patients

In a notable Genomic Press research report, researchers at the Aristotle University of Thessaloniki have uncovered a significant presence of manic symptoms in patients with schizophrenia spectrum disorders (SSDs), offering valuable insights that could reshape treatment approaches.

11 Feb 2025

UCLA Health launches study on ketogenic diet for bipolar disorder in youth

UCLA Health is set to begin a multi-site pilot study to explore whether a ketogenic diet, when combined with mood stabilizing medications, helps stabilize mood symptoms in teenagers and young adults who have bipolar disorder.

8 Feb 2025

New genomic insights could transform bipolar disorder treatment

Study published in Nature identifies nearly 300 genomic regions associated with bipolar disorder, and 36 key genes involved in the disease.

23 Jan 2025

Brain-stimulation therapy at home reduces major depression symptoms

This study highlights the efficacy of home-based tDCS in treating major depressive disorder, with significant improvements in depressive symptoms and remission.

22 Oct 2024

High-dose amphetamine use linked to increased risk of psychosis or mania

Prescribing rates for stimulants that treat attention-deficit/hyperactivity disorder (ADHD) have increased significantly over the past decade, with some of the largest increases reported during the COVID-19 pandemic.

12 Sep 2024

Exploring the impact of thyroid hormone on brain function

Thyroid hormone plays a key role in regulating a range of physiologic functions, including metabolism, temperature, heart rate, and growth. It accomplishes this impressive array of activities by interacting with almost every organ system in the body. Yet despite a long history of research on how thyroid hormone influences different organs, its effects on arguably the most crucial organ - the brain - have remained shrouded in mystery.

23 Aug 2024

Perimenopausal women face increased risk of depression and mania, study reveals

Explore why women may be at higher risk of developing mania and major depressive disorder during perimenopause.

19 Aug 2024

Study: Omega-6 fatty acids could reduce the risk of bipolar disorder

Omega-6 fatty acids, commonly found in eggs, poultry, and seafood, could reduce the risk of bipolar disorder, according to a world-first study from the University of South Australia.

6 May 2024

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder, according to a new study in Biological Psychiatry, published by Elsevier.

30 Apr 2024

Women predominantly treated for anxiety and depression at psychiatric outpatient clinics

More than 75% of the patients treated at the psychiatric outpatient clinic of Hospital de Base in São José do Rio Preto, São Paulo state (Brazil), are women with a mean age of 45 and suffering from sadness, anxiety and irritability, according to a study reported in the journal Frontiers in Psychiatry.

13 Apr 2024

Electroconvulsive Therapy found to be safe and effective treatment for some mental illnesses

Researchers have found that Electroconvulsive Therapy (ECT), where an electric current is passed through the brain, can reduce the severity of mental illnesses.

9 Apr 2024

Study reveals ADHD medication reduces psychiatric hospitalizations and work disability

Study highlights the benefits and potential risks of ADHD medication, revealing that stimulants like amphetamines and methylphenidate reduce the risk of psychiatric hospitalization and improve long-term employment outcomes, though concerns about adverse effects such as increased heart rate and potential for triggering psychosis or mania remain.

24 Mar 2024

Bipolar disorder cuts lives short more than smoking

Having bipolar disorder – a serious mental illness that can cause both manic and depressed moods – can make life more challenging.

4 Jan 2024

Study investigates the connection between changing light levels and mental health

In Finland, there is a clear increase in the number of sick days taken due to depression, anxiety and sleep disorders in October and November, whereas the number of absences is lower than expected between June and September.

20 Dec 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

UCLA Health participates in new study gathering extensive data about people with bipolar disorder

A new study is gathering extensive data about people with bipolar disorder to improve diagnosis and treatment of this mental health condition that affects 40 million people worldwide, according to the World Health Organization.

20 Oct 2023

Doctors abandon a diagnosis used to justify police custody deaths. It might live on, anyway.

Brooks Walsh hadn't questioned whether "excited delirium syndrome" was a legitimate medical diagnosis before the high-profile police killings of Elijah McClain in Colorado in 2019 and George Floyd in Minnesota in 2020.

16 Oct 2023

Daylight heals, night light steals: The surprising link between light exposure and mental health

Researchers find that increased night-time light exposure is linked to higher risks of various psychiatric disorders including depression and anxiety, while more daylight exposure lowers these risks. The large-scale study suggests modulating light patterns could be a non-pharmacological strategy for improving mental health.

12 Oct 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023