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Scientists studied diet and lung cancer in 95,612 adults. One eating pattern stood out

A prospective study of 95,612 U.S. adults found that those with the highest sulfur microbial diet scores had a 23% higher adjusted lung cancer incidence hazard and a 19% higher lung cancer-related mortality hazard than those with the lowest scores. However, the associations weakened after accounting for overall dietary quality and competing causes of death, and the findings do not establish a causal relationship.

13 Oct 2026

Buck Institute and Georgetown lead effort mapping harmful protein changes before disease begins

A research "super team" co-led by theBuck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments.

12 Oct 2026

Study reveals how different plant saponins alleviate ischemic stroke

Ischemic stroke accounts for approximately 85% of all strokes and remains a major cause of death and long-term disability.

12 Oct 2026

UCLA scientist develops new way to map cellular metabolism

Nutrition advice is everywhere. Eat more protein. Cut back on sugar. Get more fiber. But beneath all that advice is a surprisingly basic gap in our understanding: Scientists still have a limited view of what happens when specific nutrients reach individual cells inside the body.

6 Oct 2026

Cranberry juice doesn’t affect every woman the same way

Cranberry juice's effectiveness against UTIs varies among women due to metabolic differences, impacting urinary anti-adhesion activity and pathogen response.

6 Oct 2026

Eating walnuts daily may boost mood and shift serotonin-related metabolism

Daily walnuts improve mood and alter serotonin-related metabolites in young adults.

2 Oct 2026

Gut bacterial metabolite worsens brain damage after stroke, study finds

Researchers at LMU have discovered how a metabolite produced by gut bacteria can influence brain damage after stroke.

1 Oct 2026

Esophageal cancer leaves a distinct metabolic signature in the gut

The study uncovers gut microbial and metabolic signatures in esophageal cancer, emphasizing lipid dysregulation and its potential role in disease progression.

1 Oct 2026

Intestinal enzyme links microbial metabolism to MASH progression

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis. A new study published in eGastroenterology shifts attention upstream, identifying intestinal neutral ceramidase as a gut-derived driver of MASH progression through its effects on microbial metabolism, epithelial signalling and intestinal barrier function.

29 Sep 2026

Exercise may reshape your gut microbiome to support recovery

Research reveals how exercise alters gut microbes, influencing recovery and proposing 'intestinal rehabilitation' for those with limited exercise capacity.

29 Sep 2026

From espresso to filter coffee, brewing may shape what reaches your gut

A focused narrative review traces how caffeine, chlorogenic acids, and coffee fibers move through the gut and interact with microbes. The authors identify plausible links between the microbiome and liver health, but human studies have not shown that microbiome changes cause coffee’s reported metabolic benefits.

28 Sep 2026

Blood markers linked to healthy eating may reflect more than food choices

Researchers analyzed dietary data from 204,938 UK Biobank participants and identified blood protein and metabolite profiles associated with adherence to the EAT-Lancet diet. These profiles showed stronger links to several health outcomes and modeled life expectancy than the diet score, but the observational study cannot establish that the diet caused those differences.

28 Sep 2026

An AI-identified biomarker can look accurate and still fail its biggest test

The review examines how AI combines molecular, imaging, circulating, cellular, and digital data to identify potential disease biomarkers. Its authors argue that independent validation, biological testing, and evidence of better clinical decisions are needed before those candidates enter patient care.

28 Sep 2026

Why one gut microbe is attracting attention in heart failure research

Researchers found that chronic systolic heart failure caused by nonischemic cardiomyopathy was associated with reduced gut microbial diversity, depletion of Bifidobacterium, and lower microbial short-chain fatty acid production potential. Higher Bifidobacterium abundance and higher circulating indole-3-propionic acid levels were associated with milder disease and clinical improvement, although the findings do not establish causality.

27 Sep 2026

Could the Mediterranean diet protect the brain through the gut?

A narrative review finds that the Mediterranean diet may support brain health through gut microbiome, immune, metabolic, and barrier-related pathways, but direct human evidence that microbiome remodeling mediates neuroprotection remains limited. The proposed mechanisms involve microbial metabolites, reduced inflammatory signaling, stronger intestinal and blood-brain barrier function, and possible effects on processes linked to Alzheimer’s and Parkinson’s diseases.

27 Sep 2026

Gut bacteria metabolites directly extend the lifespan of host flies

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions.

24 Sep 2026

GLP-1 drugs may influence chronic pain through gut-brain and immune pathways

Researchers reviewed evidence linking GLP-1 and GLP-1 receptor agonists to chronic pain modulation through gut microbial, neuroimmune, vagal, and metabolic pathways, with the strongest clinical evidence currently involving knee osteoarthritis and idiopathic intracranial hypertension headache. Much of the proposed biology remains supported by preclinical research, and human studies have yet to establish that GLP-1RA-induced changes in the gut microbiome directly cause pain relief.

24 Sep 2026

First foods bring an early functional shift in the infant gut microbiome

Researchers analyzing paired gut microbiome samples from 125 Irish infants found that complementary feeding was associated with early changes in microbial composition and metabolic potential, including an increased capacity for complex carbohydrate metabolism. Breastfeeding duration was more closely associated with microbial community development than the timing of solid-food introduction, while formula-fed infants showed more extensive functional pathway changes after solids were introduced.

24 Sep 2026

Children who ate healthier plant foods had slightly lower blood pressure later

Researchers followed 3,990 Dutch children for an average of 1.6 years and found that higher healthful plant-based diet scores were associated with modestly lower blood pressure and total cholesterol. Children with higher unhealthful plant-based diet scores had lower estimated food costs and distinct metabolite profiles, while healthful scores showed no clear cost association.

22 Sep 2026

Regular exercisers show distinct metabolic and immune signatures in blood

Researchers compared blood samples from 40 regular exercisers and 46 sedentary adults and found differences in metabolites, blood chemistry, and immune cell gene activity. The patterns suggested greater fatty acid use and altered immune signaling among exercisers, but the study could not establish that exercise caused these differences.

21 Sep 2026