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Trial findings do not support prasugrel monotherapy at the time of primary PCI for STEMI patients

Monotherapy using prasugrel failed to show noninferiority compared with potent antiplatelet therapy plus aspirin at the time of primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.

29 Aug 2026

Potent antiplatelet therapy increases bleeding risk after heart attack in AF patients

Potent antiplatelet therapy increased bleeding without signs of benefit regarding cardiovascular events in patients with atrial fibrillation after a heart attack.

29 Aug 2026

Atorvastatin reduces major cardiovascular events but misses disability-free survival goal

Atorvastatin reduced major cardiovascular events by 30% in older people without known cardiovascular disease, diabetes or dementia, but did not significantly improve disability-free survival, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

29 Aug 2026

New findings do not support the use of edoxaban in AF patients after intracranial hemorrhage

Edoxaban did not reduce stroke or systemic embolism but increased major bleeding in high-risk patients with atrial fibrillation who had had an intracranial hemorrhage, according to results presented in a Hot Line session today at ESC Congress 2026.

29 Aug 2026

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

The U.S. Food and Drug Administration (FDA) has approved daraxonrasib, an oral multi-selective RAS(ON) inhibitor, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or are not candidates for multiagent systemic therapy.

From Dana-Farber Cancer Institute, Inc. 29 Aug 2026

Researchers uncover molecular pathway driving craniosynostosis

Craniosynostosis is a congenital developmental disorder in which the skull's cranial sutures fuse prematurely.

28 Aug 2026

POET-II trial reduces antibiotic duration for infective endocarditis by two weeks

A response-tailored strategy reduced antibiotic duration by two weeks without compromising the safety of patients with left-sided infective endocarditis.

28 Aug 2026

Oral anticoagulants benefit patients with atrial fibrillation at intermediate stroke risk

Oral anticoagulant therapy lowered the risk of adverse clinical events compared with no anticoagulation in patients with atrial fibrillation at intermediate stroke risk, according to results from the SINGLE-AF trial presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

28 Aug 2026

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

27 Aug 2026

Metformin cuts preterm birth risk among high-risk mothers

A common diabetes medication can reduce the risk of early and preterm births for mothers at high metabolic risk, according to new research led by Monash University.

26 Aug 2026

New review examines oral cancer drug delivery barriers and strategies

Delivering drugs directly to oral tumor sites remains challenging. A recent review involving researchers from Hasanuddin University examines barriers to local drug delivery and analyses strategies for targeting oral cancer lesions.

26 Aug 2026

Artificial sweetener xylitol associated with higher risk of adverse cardiovascular events

A study to be presented at ESC Congress 2026 will show that high blood levels of the artificial sweetener, xylitol, were associated with increased risk of major adverse cardiovascular events.

26 Aug 2026

Sugar tax could prevent millions of cases of tooth decay in Australia

Millions of cases of tooth decay could be prevented if Australia introduced a 20 per cent tax on sugar, new Griffith University research has found.

25 Aug 2026

A year after women lost weight, researchers saw which health gains lasted and which faded

Diet-induced weight loss significantly reduced predicted 10-year risks of major adverse cardiovascular events and type 2 diabetes in healthy premenopausal women with overweight, regardless of whether aerobic or resistance exercise was added. Some of these gains diminished as weight was partially regained over the following year, although greater exercise adherence was associated with less rebound in predicted diabetes risk.

25 Aug 2026

What decades of wine research can, and cannot, tell us about health

A narrative review found that moderate wine intake has repeatedly been associated with lower all-cause and cardiovascular mortality, with proposed mechanisms involving ethanol and grape-derived polyphenols, but the evidence remains largely observational and cannot establish causation. The authors argue that drinking pattern, beverage type, age, cancer risk, and risk-modeling choices all influence how the J-shaped association should be interpreted and how alcohol guidelines are developed.

25 Aug 2026

Oral News and Research

Trial findings do not support prasugrel monotherapy at the time of primary PCI for STEMI patients

Potent antiplatelet therapy increases bleeding risk after heart attack in AF patients

Atorvastatin reduces major cardiovascular events but misses disability-free survival goal

New findings do not support the use of edoxaban in AF patients after intracranial hemorrhage

FDA approves daraxonrasib for metastatic pancreatic cancer following landmark clinical trial led by Dana-Farber

Researchers uncover molecular pathway driving craniosynostosis

POET-II trial reduces antibiotic duration for infective endocarditis by two weeks

Oral anticoagulants benefit patients with atrial fibrillation at intermediate stroke risk

FDA approves first RAS-targeted therapy for metastatic pancreatic cancer

Metformin cuts preterm birth risk among high-risk mothers

New review examines oral cancer drug delivery barriers and strategies

Artificial sweetener xylitol associated with higher risk of adverse cardiovascular events

Sugar tax could prevent millions of cases of tooth decay in Australia

A year after women lost weight, researchers saw which health gains lasted and which faded

What decades of wine research can, and cannot, tell us about health

New study makes progress in understanding the mechanisms behind severity of HFpEF

Yeast-based nanoparticle vaccine could make annual flu shots obsolete

Type 2 diabetes incidence increases 10-fold among American youth

Type 2 diabetes mechanisms differ significantly based on patient BMI

Nanoparticle vaccine offers long-lasting protection against multiple flu strains

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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