Orthopaedic News and Research

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Age-related muscle loss linked to increased tumor growth

Duke-NUS scientists have discovered that aging muscle may contribute to cancer growth by releasing fewer extracellular vesicles, tiny particles that cells use to communicate with one another.

16 Jun 2026

$2 million NIH funding supports wearable knee exoskeleton research

Building on the success of projects to boost strength by adding motors to conventional knee, hip and ankle braces, a University of Michigan team is exploring how well this approach could work for relieving knee pain from osteoarthritis.

1 Jun 2026

Senolytic therapy delays early disc degeneration in mouse model

Targeting senescent cells with dasatinib-quercetin preserves disc structure and modulates degeneration-associated pathways in a mouse model.

25 May 2026

Key gene variants tied to developmental dysplasia of the hip and osteoarthritis

Developmental dysplasia of the hip (DDH) is a polygenetic disorder that increases the risk of hip osteoarthritis.

17 Apr 2026

University of Cincinnati launches clinical trial to test new drug for prosthetic joint infections

The University of Cincinnati has enrolled the first patients in a new clinical trial that will test the effectiveness of an investigational drug for prosthetic joint infections (PJI).

10 Apr 2026

Cellular roadmap offers new targets for improving rotator cuff surgical repair

Rotator cuff tears are among the most common and debilitating musculoskeletal injuries, frequently causing chronic pain, reduced shoulder mobility, and a high risk of re-injury even after surgical repair.

9 Mar 2026

Studies highlight benefits of osseointegration for patients with limb amputations

Three new studies from Hospital for Special Surgery (HSS) highlight the use and advantages of osseointegration (OI) for individuals with an amputation, in some instances challenging prevailing beliefs about which patients would benefit.

6 Mar 2026

Small RNA molecules can accurately predict survival in older adults

As people age, it becomes harder to know who is on track for healthy years ahead and who may be at higher risk for serious decline.

25 Feb 2026

Duplicate medical records linked to higher hospital death risk

Patients with duplicate medical records are 5 times more likely to die after being admitted to hospital and 3 times more likely to require intensive care than those with a single medical record, reveals US research published online in the journal BMJ Quality & Safety.

3 Feb 2026

Cardiology consults post-surgery may reduce heart risks and mortality rates

An estimated 4.2 million people die within 30 days of surgery worldwide each year. A new study, published in the European Heart Journal today (Thursday), suggests that deaths and serious heart disease might be prevented if some patients see a specialist heart doctor as part of their post-surgery care.

30 Jan 2026

$Six week casting proves as effective as surgery for unstable ankle fractures$

Six week casting proves as effective as surgery for unstable ankle fractures

Wearing a cast for six weeks appears to be no less effective than surgery for healing unstable ankle fractures and carries fewer treatment related harms, finds a clinical trial from Finland published by The BMJ today.

14 Jan 2026

HIF1 protein identified as key driver of tendon pain

Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems.

14 Jan 2026

Postoperative complications of medical tourism place growing financial burden on the NHS

The postoperative complications of medical tourism may be costing the NHS up to £20,000 per patient, suggest the findings of a rapid review of the available data, published in the open access journal BMJ Open.

13 Jan 2026

Day case surgery linked to significant readmission and chronic pain risks

Two new studies published in Anaesthesia (the journal of the Association of Anaesthetists) analyzing pain and other factors connected with day surgery in the UK show that around 1 in 8 patients having day-case surgery end up not going home and instead are admitted to hospital for various complications.

7 Jan 2026

Orthopedic encounters could play key role in early detection of intimate partner violence

A study by researchers at Mass General Brigham highlights the opportunity for orthopedic surgeons to play a critical role in identifying patients who have experienced intimate partner violence (IPV).

5 Jan 2026

Hypertrophic chondrocytes play a crucial role in bone growth and repair

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into bone-building cells or osteoblasts, and the formation of new blood vessels to supply the newly formed bone tissue.

13 Dec 2025