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UVA Health scientists pioneer a new way to create vaccines far more quickly than ever before

UVA Health scientists are reporting promising success as they pioneer a new way to create vaccines far more quickly, nimbly and inexpensively than ever before.

28 Jan 2026

Sub-lethal water disinfection can unintentionally boost the spread of antibiotic resistance

The study reveals that environmental stressors do not merely kill bacteria; they can also prime surviving cells to take up resistance genes more efficiently, raising concerns about how antibiotic-resistant bacteria may spread in aquatic environments.

8 Jan 2026

Plasmid-borne resistance drives global expansion of dangerous Klebsiella strains

A recent study published in Engineering has shed light on the transmission and epidemiological trends of tmexCD1-toprJ1-positive Klebsiella pneumoniae across various ecological niches, highlighting the potential threat this antibiotic-resistant bacterium poses to global public health.

31 Dec 2025

New single-cell method reveals how plasmids drive antibiotic resistance

Researchers in the Blavatnik Institute at Harvard Medical School have just opened a new window into understanding the development of antibiotic resistance in bacteria.

20 Nov 2025

BIOVECTRA and Revolution Biomanufacturing partner to deliver integrated mRNA Design and GMP production services

BIOVECTRA, a part of Agilent Technologies Inc., and Revolution Biomanufacturing Inc. today announced a collaboration that grants BIOVECTRA access to Revolution Biomanufacturing's proprietary platforms for optimizing untranslated regions (UTRs) and codon usage to enhance mRNA stability and translational efficiency.

6 Nov 2025

PlasmidFactory and Fraunhofer IZI join forces to advance non-viral cell and gene therapies

PlasmidFactory GmbH and the Fraunhofer Institute for Cell Therapy and Immunology IZI have signed a Memorandum of Understanding to combine expertise in cell therapy process development and GMP manufacturing, aiming to accelerate non-viral cell and gene therapies for the benefit of patients.

From PlasmidFactory GmbH 9 Oct 2025

Mapping 100 years of bacterial evolution reveals key spreaders of antibiotic resistance

The genetic culprits responsible for the spread of multidrug resistance (MDR) in bacteria have been identified by new research mapping 100 years of bacterial evolution.

25 Sep 2025

Why Salmonella Dublin poses a food safety threat in beef and dairy

The study on Salmonella Dublin highlights its genomic similarities and resistance traits, raising concerns for food safety and antimicrobial resistance.

27 Aug 2025

Probiotics limit the spread of drug-resistant genes in preemies

Study reveals probiotics help preterm infants develop healthier gut microbiomes, reducing multidrug-resistant bacteria and enhancing neonatal care outcomes.

26 Aug 2025

Epstein-Barr virus protein enhances cancer gene activity in HPV-positive cervical cells

A new research paper was published in Volume 16 of Genes & Cancer on August 6, 2025, titled "Epstein-Barr virus nuclear antigen 1 upregulates Derlin1 and PSMD10 expression in HeLa cells."

22 Aug 2025

New strategies to tackle resistant foodborne pathogens

Innovative approaches in food and beverage analysis are transforming pathogen detection and control, emphasizing the role of natural compounds and sequencing.

19 Aug 2025

Study shows probiotics help preterm babies fight antibiotic-resistant bacteria

Researchers found that probiotics help reduce antibiotic-resistant bacteria in the guts of very-low-birth-weight preterm infants, but cannot fully prevent resistance genes from spreading. Antibiotic use still promotes gene swapping, highlighting the limits of probiotics alone in neonatal care.

17 Aug 2025

Revolutionizing therapeutic protein design with synthetic biology

In medicine and biotechnology, the ability to evolve proteins with new or improved functions is crucial, but current methods are often slow and laborious.

8 Aug 2025

Promega Plasmid Collection, available through Addgene, equips industry and academic researchers with powerful bioluminescent assays that provide deeper insights into endogenous cellular biology

Addgene, a purpose-driven organization helping scientists conduct experiments with greater ease, speed, and reproducibility, today announced a strategic partnership with Promega to expand Addgene’s vast plasmid repository with the launch of the Promega Plasmid Collection.

From Promega Corporation 31 Jul 2025

Innovative nanopore system enables controlled DNA unzipping

DNA holds the instructions that make us who we are. If we want to read those instructions, say to understand our predisposition to genetic disorders, we need to carefully 'unzip' DNA's iconic double-helix structure.

30 Jul 2025

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

Blocking a single gene disrupts vitamin D metabolism and cancer pathways in new cell study

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells. Disruption of this enzyme altered cancer-related pathways and cell viability, highlighting its potential as a therapeutic target.

21 Jul 2025

Ionophore use in farming drives global spread of antibiotic resistance genes, study finds

Researchers identified the widespread presence of the ionophore resistance genes narA and narB in over 2,400 bacterial isolates across 51 countries. These genes are often genetically linked to resistance against critically important human antibiotics, raising concerns over agricultural practices and global antimicrobial resistance.

30 Jun 2025

Seafood imports linked to spread of colistin resistance

Colistin is a potent, last-resort antibiotic, used only to treat people with dangerous, life-threatening bacterial infections that have developed resistance to other drugs.

22 Jun 2025

Engineered viruses and gene therapy halt tumor growth and extend survival in mice

This study reveals the potential of engineered phage-IL-12 therapy in melanoma, enhancing immune response and tumor destruction in aggressive cancer models.

2 Jun 2025