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Prenatal progesterone exposure alters brain development genes in male fetuses

Excessive exposure to progesterone in the womb can alter a gene in the frontal cortex in male sheep fetuses, which is needed for brain development and function, according to research presented at the 28th European Congress of Endocrinology in Prague.

11 May 2026

AI-driven hormone tracking could help detect infertility early and improve conception

Men and women who appear hormonally 'normal' may still have undetected disruptions in the timing and coordination of their reproductive hormones that could impair fertility, according to research presented at the 28th European Congress of Endocrinology in Prague.

8 May 2026

Calla Lily Clinical Care doses first patients in clinical trial for intravaginal drug delivery platform for threatened miscarriage

Calla Lily Clinical Care, a women’s health-focused medical technology company, today announced dosing of the first patients in the FREEDOM clinical trial.

6 May 2026

Higher stress and BMI tied to earlier puberty in girls

New research links stress, BMI, and hormone patterns to pubertal timing, revealing implications for long-term health and early intervention strategies.

16 Apr 2026

Steroid hormones, BMI and stress influence puberty timing in girls

Higher levels of key steroid hormones-combined with elevated stress and body mass index (BMI)-are associated with earlier onset of puberty in girls, according to a new study at Columbia University Mailman School of Public Health.

13 Apr 2026

Researchers map how menstrual cycle phases affect athletic performance

In a repeated-measures study of 18 eumenorrheic female athletes, half-squat strength was highest in the late follicular phase and around ovulation, while handgrip strength peaked in the late luteal phase. Psychological measures also shifted across the cycle, with lower vigor and higher fatigue and depression scores in the late luteal phase, supporting more individualized training monitoring.

12 Apr 2026

Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair

New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration.

10 Apr 2026

Large US study finds never-married adults face higher risk for most major cancers

A large US population-based study found that never-married adults had higher cancer incidence than ever-married adults across most cancer types, with the largest disparities seen in older adults and in Black men. The pattern was especially strong for HPV-related, tobacco-related, and several reproductive cancers, suggesting marital status may act as an important social marker of cancer risk.

9 Apr 2026

Treating autonomic dysfunction can relieve symptoms of treatment-resistant depression

Consider a house with the water main half shut. The faucets sputter. The toilet runs all night. The garden wilts. You could call a plumber for the faucet, a landscaper for the garden, a different plumber for the toilet, and every one of them would fix something while fixing nothing.

31 Mar 2026

How do diet, smoking, alcohol, and stress reshape the female microbiome?

This review examines how modifiable lifestyle and environmental factors shape the female vaginal, gut, oral, and skin microbiomes, with diet, alcohol, smoking, obesity, stress, hygiene, physical activity, and sexual behaviours all linked to site-specific microbial shifts. It argues that understanding these patterns could help guide future female-focused prevention and intervention strategies.

30 Mar 2026

Microgravity reduces the ability of sperm to navigate reproductive tracts

Having a baby in space may require a bit more direction, with new Adelaide University research revealing the navigational abilities of sperm are negatively impacted by a lack of gravity.

26 Mar 2026

Study links androgens to aggressive childhood brain tumor growth

An international team led by researchers at Baylor College of Medicine, Texas Children's Hospital, McGill University and University of Pittsburgh School of Medicine has discovered what drives the growth of a lethal pediatric brain tumor called Posterior Fossa Type A (PFA) ependymoma.

25 Mar 2026

Birth control skepticism, teen fertility education center stage at Trump’s women’s health summit

Surrounded by hot pink lights and cherry blossom pink drapes on a ballroom stage, family doctor Marguerite Duane offered a seemingly simple solution to infertility: Doctors should have conversations with young girls about whether they want to have children one day.

16 Mar 2026

Dual-positive hybrid cells linked to shorter survival in advanced breast cancer

An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

11 Mar 2026

Hormone fluctuations influence perceived effort during intense workouts

Female sex hormones estrogen and progesterone fluctuate monthly across the menstrual cycle, affecting moods and energy levels.

2 Mar 2026

Study reveals knowledge gaps about menstrual health in elite women’s football

Elite European women’s football players and staff show substantial knowledge gaps about menstrual health and hormonal contraception despite widespread openness to discussion. The study highlights the need for structured education to support informed health decisions while clarifying that perceived performance effects are not consistently supported by scientific evidence.

24 Feb 2026

Precision mRNA vaccine strategy shows early promise for improving TNBC relapse risk

An individualized neoantigen mRNA vaccine was tested in patients with early-stage triple-negative breast cancer and showed feasibility, safety, and strong T cell immune responses. Long-term follow-up suggested durable immune memory with encouraging relapse-free outcomes, though controlled trials are needed to confirm clinical benefit.

19 Feb 2026

Sustained high progesterone during pregnancy can improve menstrual cyclicity in PCOS patients

Polycystic ovary syndrome (PCOS) affects 6%−20% of reproductive-aged women, and is commonly accompanied by irregular menstrual cycles and anovulatory infertility.

11 Feb 2026

Skin-delivered estrogen improves bone health in amenorrhoa

Hormone replacement therapy applied via the skin is the best way of protecting bone density in women whose periods have stopped due to anorexia or intense exercise, according to new research from Imperial College London and Imperial College Healthcare NHS Trust.

6 Feb 2026

Hormonal contraceptives show differing heart risks among stressed women

Antonia Seligowski, PhD, of the Neurocardiac Effects of Stress & Trauma Laboratory within the Department of Psychiatry at Mass General Brigham, is the senior author of a paper published in JAMA Network Open, "Hormonal contraceptive use, stress disorders, and cardiovascular and thrombotic risk in women."

5 Feb 2026