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Long non-coding RNAs offer new pathways to overcome cancer treatment resistance

Scientists are highlighting long non-coding RNAs (lncRNAs) as promising targets in the effort to overcome one of cancer treatment's most persistent challenges: therapeutic resistance.

12 Oct 2026

RNA modification enzyme FTO shows therapeutic promise in gastrointestinal cancers

A new review in Genes & Diseases highlights FTO, an enzyme involved in RNA modification, as a potentially important biomarker and therapeutic target across gastrointestinal cancers.

12 Oct 2026

Review highlights EP4 receptor as target for inflammatory diseases

A review published in Genes & Diseases highlights the prostaglandin E2 receptor subtype 4 (EP4) as an important regulator of inflammation and a promising therapeutic target for a wide range of inflammatory and inflammation-related diseases.

12 Oct 2026

Targeting mitochondrial vulnerabilities could help treat triple-negative breast cancer

A deeper understanding of mitochondrial function could create new opportunities for treating triple-negative breast cancer (TNBC), one of the most aggressive and difficult-to-treat forms of breast cancer.

12 Oct 2026

Targeting lipophagy could help treat metabolic and oxidative stress-related diseases

A review published in Genes & Diseases highlights lipophagy, the cellular process that selectively breaks down lipid droplets, as a potentially important therapeutic target for conditions driven by disrupted lipid metabolism and oxidative stress.

12 Oct 2026

New review highlights expanding potential of therapeutic DNA vaccines

A new review published in Genes & Diseases highlights the expanding potential of DNA-based vaccines as a flexible platform for preventing infectious diseases, treating cancer and strengthening preparedness for future disease outbreaks.

12 Oct 2026

Gut bacteria may help explain why endometriosis pain varies

A study of 50 women with surgically confirmed endometriosis found that differences in gut bacterial composition were associated with menstrual pain, urinary symptoms, and infertility.

9 Oct 2026

Excess adiposity may alter the immune environment of airways to promote lung cancer

In a recent study of more than a thousand individuals, greater adiposity, or excessive body fat or fatty tissue, specifically in the abdomen, was associated with lung cancer.

8 Oct 2026

Mini-GRID radiotherapy limits cellular senescence in glioma models

A new research paper was recently published in Volume 18 of Aging, titled "Spatially fractionated mini-GRID radiotherapy differentially modulates radiation-induced senescence in murine glioma and normal cells."

6 Oct 2026

Human dental pulp stem cell secretome boosts stroke recovery

Ischemic stroke can leave lasting neurological damage after the initial vascular event, with oxidative stress, neuroinflammation, neuronal death, and disruption of neural connectivity contributing to impaired recovery.

6 Oct 2026

Stroke reshapes brain environment to accelerate glioma progression

After a stroke, the brain gets to work repairing damaged tissue. But new research suggests some of the same biological processes that aid recovery may also help tumor cells grow and spread.

1 Oct 2026

Researchers find secret protein that drives cancer cell division

A previously unknown protein, hidden in RNA thought not to encode proteins, helps cells divide correctly. The RNA molecule that encodes the protein also has a function of its own in cell division.

25 Sep 2026

MIT biologists discover cellular pathway that triggers colon cancer spread

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

24 Sep 2026

EGFR co-targeting and nanotechnology offer new triple-negative breast cancer therapies

Triple-negative breast cancer (TNBC) remains one of the most challenging forms of breast cancer to treat because it lacks the estrogen, progesterone and HER2 receptors that enable targeted treatment in other breast cancer subtypes.

24 Sep 2026

Protein modification network plays vital role in cancer development

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response.

24 Sep 2026

Review highlights how altered metabolism drives kidney cancer growth

Clear cell renal cell carcinoma (ccRCC), the most common subtype of kidney cancer, is increasingly understood as a malignancy shaped by profound changes in cellular metabolism.

24 Sep 2026

Why might a higher BMI at 20 be linked to lower breast cancer risk later in life?

A large UK cohort study found that higher BMI at age 20 was associated with lower postmenopausal breast cancer risk, while higher BMI in later adulthood was linked to increased risk. Lower VAS percentage mammographic density appeared to explain part of the early-adulthood association, while fibroglandular volume showed a different relationship with life-course adiposity.

20 Sep 2026

Scientists discover metabolite fueling aggressive brain tumor growth

Virtually all high-grade, aggressive gliomas in adults accumulate massive amounts of a metabolite called guanidinoacetate (GAA) that overstimulates nearby neurons and promotes tumor growth, according to new research from scientists at Children’s Medical Center Research Institute at UT Southwestern (CRI) published in Cell.

18 Sep 2026

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Tuberculosis (TB) remains one of the world's leading causes of death, and preventing post-treatment relapse continues to be a major worldwide health challenge.

17 Sep 2026

Shatavari may affect more than hormones, and the gut could help explain why

A review in Nutrients examined how bioactive compounds in Asparagus racemosus (Shatavari) may influence cognitive health through the microbiota-gut-brain axis, estrogen-related signaling, neuroinflammation, oxidative stress, and neurotransmitter regulation. Evidence from computational, cellular, animal, and limited human studies suggests several plausible biological pathways, but key questions remain about bioavailability, brain exposure, dosing, and clinical efficacy.

16 Sep 2026

Proliferation News and Research

Long non-coding RNAs offer new pathways to overcome cancer treatment resistance

RNA modification enzyme FTO shows therapeutic promise in gastrointestinal cancers

Review highlights EP4 receptor as target for inflammatory diseases

Targeting mitochondrial vulnerabilities could help treat triple-negative breast cancer

Targeting lipophagy could help treat metabolic and oxidative stress-related diseases

New review highlights expanding potential of therapeutic DNA vaccines

Gut bacteria may help explain why endometriosis pain varies

Excess adiposity may alter the immune environment of airways to promote lung cancer

Mini-GRID radiotherapy limits cellular senescence in glioma models

Human dental pulp stem cell secretome boosts stroke recovery

Stroke reshapes brain environment to accelerate glioma progression

Researchers find secret protein that drives cancer cell division

MIT biologists discover cellular pathway that triggers colon cancer spread

EGFR co-targeting and nanotechnology offer new triple-negative breast cancer therapies

Protein modification network plays vital role in cancer development

Review highlights how altered metabolism drives kidney cancer growth

Why might a higher BMI at 20 be linked to lower breast cancer risk later in life?

Scientists discover metabolite fueling aggressive brain tumor growth

Immunotherapy combined with BCG vaccine drastically lowers tuberculosis relapse risk

Shatavari may affect more than hormones, and the gut could help explain why

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