Renin News and Research

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Renin, also known as angiotensinogenase, is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Acute coronary syndrome (ACS) in patients with SARS-CoV-2 infection represents a critical intersection of viral-induced inflammation and cardiovascular pathology.

22 May 2025

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Researchers have found that prescribing guideline-directed medical treatment (GDMT), regardless of the number of medications, can improve survival rates in patients 90 years of age and older following their first heart attack, with the greatest benefit observed in patients who received all four recommended post-acute myocardial infarction (AMI) therapies.

22 May 2025

Egg white proteins show promise in naturally lowering blood pressure

Hypertension is a major public health concern, affecting millions worldwide and increasing the risk of heart disease, stroke, and kidney failure.

1 May 2025

Discontinuing heart failure medications increases risk of heart-related death

Patients who have been treated for heart failure and experience an improvement of their pump function, are still at higher risk of heart-related death or hospitalization if they stop taking heart failure medications.

17 Mar 2025

Malnutrition in heart failure patients associated with diminished GDMT prescription rates

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at identifying crucial gaps in guideline-directed medical therapy (GDMT) application among malnourished patients at Beijing Anzhen Hospital.

14 Mar 2025

How gut health shapes heart disease risk — and what you can do about it

A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty acids, TMAO, and inflammatory pathways. The study emphasizes the potential of prebiotics, probiotics, and dietary changes to restore gut health and reduce heart disease risk.

13 Mar 2025

Inflammation and organ damage in severe COVID-19 tied to mitochondrial dysfunction

Severe COVID-19 arises in part from the SARS-CoV-2 virus's impact on mitochondria, tiny oxygen-burning power plants in cells, which can help trigger a cascade of organ- and immune system-damaging events, suggests a study by investigators at Weill Cornell Medicine, Johns Hopkins Medicine, Children's Hospital of Philadelphia, and the University of Pittsburgh School of Medicine, along with other members of the COVID-19 International Research Team.

3 Dec 2024

Study reveals pathways behind organ damage in severe COVID-19

New research published in the journal Proceedings of the National Academy of Sciences sheds light on the pathways that drive organ damage and death in severe COVID-19 and helps explain why survivors of the disease can experience long-term complications.

2 Dec 2024

Researchers discover new cause of cytokine storm in COVID-19

As part of the COVID-19 International Research Team, researchers at the Johns Hopkins Kimmel Cancer Center, Children's Hospital of Philadelphia, the University of Pittsburgh and Weill Cornell Medicine discovered a novel cause of cytokine storm - the extreme inflammatory response associated with increased risk of death in COVID-19 infection.

2 Dec 2024

Understanding the pathophysiological relationship between OSA and metabolic syndrome

Cardiovascular diseases remain a leading cause of mortality globally, particularly among individuals with both obstructive sleep apnea (OSA) and metabolic syndrome (MetS).

27 Nov 2024

UVA researchers discover how blood pressure medications affect kidneys

University of Virginia School of Medicine researchers have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood.

21 Nov 2024

Blood pressure control improved with dual medication pills in India

Medication variations that combined two of three different blood pressure-lowering medications into a single pill worked equally well in reducing blood pressure and were safe among adults in India, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Preeclampsia and COVID-19 share pathophysiological similarities in pregnant women

During the COVID-19 pandemic, above all before vaccines were available, an alarm was sounded regarding a possible correlation between severe cases of COVID-19 in pregnant women and preeclampsia, a condition characterized by high blood pressure (hypertension) in the expectant mother and high levels of protein in her urine (proteinuria). It can entail dangerous complications for mother and baby.

7 Nov 2024

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Researchers investigate the clinical efficacy of semaglutide in controlling urine albumin-to-creatinine ratio in overweight patients with chronic kidney disease.

31 Oct 2024

Ozempic effective for patients with chronic kidney damage

In a 24-week trial, semaglutide led to a 52% reduction in albuminuria and improved kidney health in individuals with chronic kidney disease and obesity.

28 Oct 2024

Bioactive peptides from Chlorella vulgaris for therapeutic applications

Chlorella vulgaris is a green, photosynthetic microalga in the phylum Chlorophyta. The goal of our study was to perform a bioinformatics analysis of Photosystem I P700 chlorophyll a apoprotein A2, one of its photosynthesis-related proteins, and to hunt for potent bioactive peptides.

27 Oct 2024

NIH awards grant to study how dilated cardiomyopathy progresses to heart failure

A University of Arizona College of Medicine – Phoenix researcher was recently awarded a $1.9 million National Institutes of Health grant to study the molecular mechanisms of how dilated cardiomyopathy progresses to heart failure, which could eventually lead to better preventive and treatment options for heart failure.

27 Sep 2024

Renin News and Research

Further Reading

Integrating phytomedicine and nanotechnology in managing COVID-19 related heart disease

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Egg white proteins show promise in naturally lowering blood pressure

Discontinuing heart failure medications increases risk of heart-related death

Malnutrition in heart failure patients associated with diminished GDMT prescription rates

How gut health shapes heart disease risk — and what you can do about it

Inflammation and organ damage in severe COVID-19 tied to mitochondrial dysfunction

Study reveals pathways behind organ damage in severe COVID-19

Researchers discover new cause of cytokine storm in COVID-19

Understanding the pathophysiological relationship between OSA and metabolic syndrome

UVA researchers discover how blood pressure medications affect kidneys

Blood pressure control improved with dual medication pills in India

Preeclampsia and COVID-19 share pathophysiological similarities in pregnant women

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Ozempic effective for patients with chronic kidney damage

Bioactive peptides from Chlorella vulgaris for therapeutic applications

NIH awards grant to study how dilated cardiomyopathy progresses to heart failure

Epigenetic switch controls renin production in unexpected cell type

Understanding the role of TIPS in improving renal function amid cirrhosis

How plant-based, Mediterranean, and Western diets affect gut microbiota and disease

Industry Focus eBook - Cell biology (5th edition) eBook

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

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