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Study identifies new targets for antiviral drugs against coronaviruses

A study led by researchers at the University of California San Diego School of Medicine and University of California, Riverside (UCR) School of Medicine has identified new targets for antiviral drugs against coronaviruses, including SARS-CoV-2, the virus that causes COVID-19.

2 Nov 2026

New strategy exploits a hidden genetic vulnerability in multiple cancers

Researchers have found a surprisingly common vulnerability in a broad variety of cancers and have begun designing drug compounds to exploit it, in a study led by investigators at Weill Cornell Medicine.

2 Nov 2026

Randomized trial demonstrates enhanced stent expansion in severely calcified coronary nodules

A randomized clinical trial at The Mount Sinai Hospital found that combining two techniques for removing calcium nodules-rotational atherectomy and intravascular lithotripsy (IVL)-before coronary stent placement allowed stents to expand more fully than IVL alone in patients with calcified coronary nodules.

2 Nov 2026

New project explores treatments to protect the brain from alphavirus infections

A breakthrough in the fight against mosquito-borne viruses could one day help protect patients from devastating neurological complications.

30 Oct 2026

Nanoscale particle shows potential as customizable delivery vehicle for personalized cancer vaccines

A nanoscale particle with a unique structure, developed at MIT, holds potential as a customizable delivery vehicle for personalized cancer vaccines.

30 Oct 2026

Space-grown organoids better replicate aggressive glioblastoma tumors

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults and is one of the most aggressive and deadly forms of cancer.

30 Oct 2026

Insilico Medicine leader shares AI-driven drug discovery insights in Shanghai and Dubai

Dr. Jue Wang, Head of Global Business Development at Insilico Medicine, has been invited to attend the China Healthcare Summit in Shanghai. On the afternoon of November 3 at 16:45, she will deliver a keynote speech in the panel titled: "THE COMMODITIZATION TRAP: WHO WINS WHEN EVERYONE HAS THE SAME AI?"

30 Oct 2026

Hyperactive cancer-promoting proteins help tumor cells evade immune attack

The immune system may recognize a cancer cell and still fail to destroy it. Researchers at Hiroshima University and their international collaborators found that hyperactive YAP and TAZ (YAP/TAZ), two cancer-promoting proteins, were associated with genomic instability that may make cancer cells more recognizable to the immune system, while also increasing PD-L2, which helps the cells suppress T-cell attack.

30 Oct 2026

Platelet hyperactivity drives glioblastoma progression and deep vein thrombosis

New Cleveland Clinic research published in Cancer Cell shows that people with glioblastoma have more active platelets, which are cells involved in blood clotting. Platelets also communicate with other cells and can influence immune activity. The overactive platelets in people with glioblastoma slow the activity of cancer-fighting T cells, which can contribute to tumor growth and cancer progression.

30 Oct 2026

New study reveals why colorectal cancer is more aggressive in youth

Dana-Farber Cancer Institute researchers, along with Mass General Brigham researchers from the Gene Lay Institute of Immunology and Inflammation, and the Broad Institute, have uncovered biological clues to why colorectal cancer can behave more aggressively in younger people.

29 Oct 2026

Revvity launches Signals LabGistics solution to connect and orchestrate scientific workflows

Revvity, Inc. announced that its Revvity Signals Software business is launching the Signals LabGistics™ solution, an AI-first, scientific workflow orchestration solution designed to connect and coordinate processes, workflows, and tasks from discovery to manufacturing.

From Revvity Signals Software Inc. 29 Oct 2026

Human challenge study reveals how preexisting immunity affects dengue

Dengue virus is especially pernicious compared with many other viruses, as secondary infections can actually be worse than the first one.

28 Oct 2026

Mindfulness-based behavioral therapy changes brain responses to reduce opioid cravings

Mindfulness-Oriented Recovery Enhancement (MORE), a behavioral therapy used alongside medication treatment, may help people with opioid use disorder respond differently to drug-related cues and natural rewards, according to a randomized clinical trial led by researchers at the Icahn School of Medicine at Mount Sinai.

28 Oct 2026

Brain development eliminates flawed neurons to ensure genomic integrity

During fetal development, the human brain generates an excess of neurons, most of which are eliminated shortly before and after birth.

28 Oct 2026

Study identifies common mechanism behind widespread cancer mutations

A family of mutations seen in about 20% of human cancers drives malignancy by changing the accessibility of genes to a particular regulatory protein, according to a study by Weill Cornell Medicine investigators.

28 Oct 2026

DEBRA research invests in Topadur to advance small-molecule therapies for dystrophic Epidermolysis bullosa

DEBRA Research gGmbH, a global non-profit organization dedicated to advancing research and drug development for Epidermolysis bullosa (EB), and Topadur Pharma AG, a Swiss clinical-stage biopharmaceutical company, today announced an investment by DEBRA Research in Topadur to support a preclinical program exploring a new treatment approach for dystrophic Epidermolysis bullosa (DEB). DEB is one of the more severe forms of EB, characterized by extremely fragile skin and progressive, debilitating complications.

28 Oct 2026

Mount Sinai wins $4 million NIH grant to improve prediction of postoperative acute kidney injury

Researchers at the Icahn School of Medicine at Mount Sinai have received a five-year National Institutes of Health grant of approximately $4 million to improve prediction and prevention of postoperative acute kidney injury (AKI), a potentially serious complication after surgery.

27 Oct 2026

Therapeutics News and Research

Study identifies new targets for antiviral drugs against coronaviruses

New strategy exploits a hidden genetic vulnerability in multiple cancers

Randomized trial demonstrates enhanced stent expansion in severely calcified coronary nodules

New project explores treatments to protect the brain from alphavirus infections

Nanoscale particle shows potential as customizable delivery vehicle for personalized cancer vaccines

Space-grown organoids better replicate aggressive glioblastoma tumors

Insilico Medicine leader shares AI-driven drug discovery insights in Shanghai and Dubai

Hyperactive cancer-promoting proteins help tumor cells evade immune attack

Platelet hyperactivity drives glioblastoma progression and deep vein thrombosis

New study reveals why colorectal cancer is more aggressive in youth

Revvity launches Signals LabGistics solution to connect and orchestrate scientific workflows

Human challenge study reveals how preexisting immunity affects dengue

Mindfulness-based behavioral therapy changes brain responses to reduce opioid cravings

Brain development eliminates flawed neurons to ensure genomic integrity

Study identifies common mechanism behind widespread cancer mutations

DEBRA research invests in Topadur to advance small-molecule therapies for dystrophic Epidermolysis bullosa

Mount Sinai wins $4 million NIH grant to improve prediction of postoperative acute kidney injury

PARP1 remodels nucleosomes to help cells repair damaged DNA

Researchers call for microbiome moonshot to tackle chronic diseases

BioUK Awards 2026 celebrate outstanding achievement and breakthrough innovations from across the life sciences

Next-generation therapeutics eBook eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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