Ulcer News and Research

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Twenty-five million Americans suffer from ulcers. An ulcer is a sore or hole in the lining of the stomach or duodenum (the first part of the small intestine). People of any age can get an ulcer and women are affected just as often as men.

Helicobacter pylori (H. pylori) is a bacterium that lives on the lining of the stomach. Although we used to think that spicy food, acid, and stress were the major causes of ulcers, we now know that nine out of ten ulcers are caused by H. pylori. Medicines that reduce stomach acid may make you feel better, but your ulcer may come back. Here's the good news: Since most ulcers are caused by this bacterial infection, they can be cured with the right antibiotics.

Study could change the definition of wound closure in diabetes care

In patients with diabetic foot ulcers that looked healed and met the current definition of a closed wound, closed ulcers with functionally defective skin that lost more body water were likely to re-open, according to a new National Institutes of Health (NIH) Diabetic Foot Consortium study, led by researchers at the University of Pittsburgh and published today in Diabetes Care.

31 May 2025

Study identifies diagnostic aid to accurately predict the recurrence of diabetic foot ulcers

NIH-funded project shows that trans-epidermal water loss could indicate if wounds are fully healed.

30 May 2025

Nutritional interventions may help prevent and treat Buruli ulcer

Nutritional interventions at a community level may be the best way forward to both prevent and treat the "flesh-eating" skin infection Buruli ulcer in the fight against neglected tropical diseases (NTDs), according to a new study from the University of Surrey.

11 Mar 2025

Gender gaps in peripheral vascular disease impact diagnosis and treatment

The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

11 Mar 2025

Integrating video capsule endoscopy technology in probiotic research

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

Zinc-carrying proteins may activate PPIs in the absence of gastric acid

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems.

21 Feb 2025

Early side effects of radiation may increase long-term risk for prostate cancer patients

Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, according to a new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center.

31 Jan 2025

Pioglitazone may help prevent painful skin ulcers in people with Werner syndrome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 2, 2024, entitled "Less frequent skin ulcers among patients with Werner syndrome treated with pioglitazone: findings from the Japanese Werner Syndrome Registry."

16 Jan 2025

Herpes infections soar globally as new study reveals massive disease burden

Global estimates of HSV-1 and HSV-2 reveal a staggering disease burden, with 42.4 million new genital herpes cases and 8.8 billion GUD person-days in 2020, underscoring the urgent need for improved prevention strategies.

12 Dec 2024

Herpes infections affect 846 million people worldwide

Around 846 million people aged between 15 and 49 are living with genital herpes infections – more than 1 in 5 of this age-group globally – according to new estimates released today.

11 Dec 2024

Hospital-acquired pressure ulcers may hinder neurological recovery in spinal cord injury patients

Research led by The Ohio State University Wexner Medical Center and College of Medicine along with scientists at the Charité – Universitätsmedizin Berlin in Berlin, Germany, provides first evidence that hospital-acquired pressure ulcers are a potent risk factor for poor neurological recovery among patients with acute spinal cord injury (SCI).

9 Dec 2024

Study highlights widespread adverse events in surgical care

Adverse events affect more than a third (38%) of adults undergoing surgery, finds a study of admissions to 11 hospitals in the US state of Massachusetts, published by The BMJ today.

13 Nov 2024

Tight petticoat waist cord linked to skin cancer

A tightly tied waist cord of the underskirt (petticoat) traditionally worn under a saree, particularly in rural parts of India, may lead to what has been dubbed 'petticoat cancer,' warn doctors in the journal BMJ Case Reports after treating two women with this type of malignancy.

5 Nov 2024

Genomic technology used to improve understanding of Marjolin's ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

28 Oct 2024

Antibiotics disrupt protective gut mucus and heighten IBD risk

In a landmark study published today in Science Advances, Dr. Shai Bel and his research team at the Azrieli Faculty of Medicine of Bar-Ilan University have uncovered crucial insights into how antibiotic use increases the risk of inflammatory bowel disease (IBD).

11 Sep 2024

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Research shows elevated metformin in diabetic foot ulcer exudates when combined with insulin, highlighting potential for improved wound healing therapies.

9 Sep 2024

Combined use of insulin and metformin enhances diabetic foot ulcer healing, research shows

People with chronic diabetic foot ulcers could soon have a new way to treat their wounds for faster healing and fewer hospital stays.

4 Sep 2024

NIAID awards grants for 10 projects to improve diagnostic tools for syphilis

The National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) has awarded grants for 10 projects to improve diagnostic tools for congenital and adult syphilis - conditions currently diagnosed with a sequence of tests, each with limited precision.

3 Sep 2024

Autofluorescence imaging improves accuracy of wound debridement

Over 6.5 million Americans experience chronic wounds - wounds that do not heal after a few months.

27 Aug 2024

MP Biomedicals announces the launch of advanced gastrointestinal diseases diagnostic kits

MP Biomedicals completes its range of in vitro diagnostic tests for infectious diseases with new immunochromatographic-based qualitative rapid tests.The new diagnostic kits by MP Biomedicals leverage cutting-edge technology to deliver precise results, enabling healthcare professionals a rapid and accurate detection of Helicobacter pylori, Salmonella typhi and Vibrio cholerae serogroups O1 and O139.

From MP Biomedicals, LLC 27 Aug 2024