Xenotransplantation News and Research

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Xenotransplantation poised to become a clinical reality soon

Speaking today at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation in Prague, Muhammad Mohiuddin, MBBS, said xenotransplantation, hailed as the future of organ transplantation, is poised to become a clinical reality within the next several years.

12 Apr 2024

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's.

27 Mar 2024

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models.

22 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Science, Innovation, and Xenotransplantation: A Discussion with Dr. Wenning Qin

In this interview, we delve deep into the pioneering world of xenotransplantation and the evolving landscape of gene editing.

2 Nov 2023

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers used a genetically engineered porcine donor to develop kidney grafts.

11 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

After world's first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.

25 Sep 2023

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

After 61 days of observation, NYU Langone Health doctors this month completed the longest-documented case of a genetically engineered pig kidney functioning in a human body.

14 Sep 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Insights gained from genetically modified pig heart transplantation

Researchers described a genetically engineered pig cardiac xenotransplantation in a 57-year-old male patient.

3 Jul 2023

Single-cell transcriptomic analysis reveals specific cellular signatures for kidney transplant rejection

Imagine a day when a urine test could inform a doctor precisely why a kidney transplant patient was experiencing organ rejection and suggest the best medication for specifically addressing the problem.

28 Jun 2023

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Dr Philip Cardiff, Associate Professor at University College Dublin's School of Mechanical and Materials Engineering, has received a European Research Council (ERC) Consolidator grant of €2 million for his 5-year project XenoSim.

1 Jun 2023

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

As part of the worldwide effort to facilitate a research and clinical pathway toward successful xenotransplantation - the transplantation of living cells, tissues and organs from one species to another - two Johns Hopkins Medicine surgeons, Kazuhiko Yamada, M.D., Ph.D., and Andrew Cameron, M.D., Ph.D., will receive a total of $21.4 million in funding over the next two years under two sponsored research agreements with biotechnology company United Therapeutics Corporation.

29 Mar 2023

Xenotransplantation News and Research

Xenotransplantation poised to become a clinical reality soon

Xenotransplantation model used for studying microglial response to Alzheimer's disease

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Science, Innovation, and Xenotransplantation: A Discussion with Dr. Wenning Qin

Towards xenotransplantation: Genetically altered pig kidneys prove viable in non-human primates

Researchers explore immunomodulating targets for improving glioblastoma therapies

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

NYU Langone doctors complete longest-documented case of pig kidney transplant in human body

Pig kidney xenotransplantation continues to function well after 32 days

Insights gained from genetically modified pig heart transplantation

Single-cell transcriptomic analysis reveals specific cellular signatures for kidney transplant rejection

UCD researcher receives ERC Consolidator grant to unlock computational insights into cardiac xenotransplantation

Johns Hopkins Medicine surgeons to receive $21.4 million to advance xenotransplantation research

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

First pig-to-human cardiac transplant alters heart's electrical signals

The successful transplantation of genetically engineered pig hearts into recently deceased humans

The emergence of infectious diseases from the "germ’s eye view”

Researchers transplant two kidneys from a genetically engineered pig into a brain-dead person

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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