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Calibr-Skaggs and Kainomyx join forces to accelerate development of antimalarial drugs

The Calibr-Skaggs Institute for Innovative Medicines at Scripps Research and Kainomyx, Inc., today announced a new research collaboration to accelerate the discovery and development of next-generation antimalarial drugs.

17 Feb 2026

Public health workers are quitting over assignments to Guantánamo

Rebekah Stewart, a nurse at the U.S. Public Health Service, got a call last April that brought her to tears. She had been selected for deployment to the Trump administration's new immigration detention operation at Guantánamo Bay, Cuba.

9 Feb 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Mitochondria shift toward the cell edge in response to glucose

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear.

19 Dec 2025

Prenatal exposure to hot and humid conditions worsens child growth outcomes

The dangers of heat and humidity are so well known it's become cliche to mention them. But the impacts can extend farther than even scientists and doctors realized.

19 Dec 2025

Cryo-EM reveals NPFFR1 activation and guides novel ligand design

This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)-a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3 from pro-NPFFB, NPFF from pro-NPFFA) and regulates physiological processes like opioid function, pain, and energy homeostasis.

13 Dec 2025

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Synaptic plasticity — the brain's ability to modify the connections between neurons to support learning — is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function.

10 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Protein network locks ABCC4 transporters in place to maintain cyclic AMP signaling levels

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways accidentally, cAMP levels must be maintained around their point of origin and at the right level.

5 Dec 2025

Study explores how elevated growth hormone levels contribute to liver aging

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 3, 2025, titled "Growth hormone excess drives liver aging via increased glycation stress."

18 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

While politicos dispense blame, these doctors aim to take shame out of medicine

The distress that Will Bynum later recognized as shame settled over him nearly immediately.

5 Nov 2025

Global study suggests potential for universal vaccine against Haemophilus influenzae

A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.

31 Oct 2025

At the hollow in Florida, the ‘medical freedom’ movement finds its base camp

MAGA and MAHA are happily married in Florida, and nowhere more at home than in Sarasota County, where on a humid October night a crowd of several hundred gathered to honor state Surgeon General Joseph Ladapo, his wife, and an unlicensed Canadian radiologist who treats cancer with horse paste.

31 Oct 2025

Study uncovers key protein complex controlling sperm motility and male fertility

Infertility affects about one in six couples, and male factors account for roughly half of all cases-often because sperm don't swim well.

13 Oct 2025

Nuclear missile workers are contracting cancer. They blame the bases.

At a memorial service in 2022, veteran Air Force Capt. Monte Watts bumped into a fellow former Minuteman III nuclear missile operator, who told him that she had non-Hodgkin lymphoma.

3 Oct 2025

Scientists study how nanoplastics transfer across generations

You can't see nanoplastics with the naked eye, but they're everywhere - including your body.

23 Sep 2025

GPR120 plays a key role in mediating the effects of n-3 fatty acids on mammary function

During lactation, the mammary gland undergoes significant structural and functional changes to produce milk, which is essential for neonatal nutrition and early immune development.

23 Sep 2025

Health care cuts threaten homegrown solutions to rural doctor shortages

Olivia Owlett chose to do her primary care residency in this Northern California college town largely because it faces many of the same health care challenges she grew up with.

18 Sep 2025

'Global Guardians' camp fosters young minds in pandemic preparedness

The Global Virus Network (GVN), in partnership with the University of South Florida (USF) Youth Experiences and Hillsborough County Public Schools STEM Department, recently concluded its inaugural "Global Guardians: Youth for Pandemic Preparedness" summer camp, an immersive, hands-on experience that brought together some of Tampa's brightest high school students with internationally renowned virologists, public health experts, and scientists.

21 Aug 2025