Cell News and Research

RSS

$5.7 million NIH grant supports research on why lean people develop insulin resistance

A Wayne State University research team was awarded a $5.7 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health focused on discovering the biological mechanisms that may help explain why some lean people develop insulin resistance while some people with obesity remain sensitive to insulin.

29 Sep 2026

Study identifies three cell clusters driving pancreatic cancer-induced cachexia

Research published today in Cell identifies three small subclusters of cells driving pancreatic cancer-induced cachexia, a muscle-wasting and fat-loss condition that makes patients less tolerant of cancer treatment.

29 Sep 2026

Neck lymph node removal surgery may disrupt brain waste clearance

Surgery to remove lymph nodes in the neck may interfere with cerebrospinal fluid (CSF) drainage from the brain, contributing to cognitive impairment, according to new multicenter research led by Weill Cornell Medicine scientists.

29 Sep 2026

Intestinal enzyme links microbial metabolism to MASH progression

Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis. A new study published in eGastroenterology shifts attention upstream, identifying intestinal neutral ceramidase as a gut-derived driver of MASH progression through its effects on microbial metabolism, epithelial signalling and intestinal barrier function.

29 Sep 2026

Bile DNA sequencing helps identify hidden pancreatobiliary tumors

Distinguishing malignant from benign biliary strictures remains a major clinical challenge. Endoscopic retrograde cholangiopancreatography (ERCP)-guided cytology and biopsy may be inconclusive, particularly in early-stage disease or when tissue is scarce.

29 Sep 2026

Targeting specific nuclear receptor could help preserve aging muscle function

Scientists in the Gerhart-Hines Group pinpoint a molecular cause of muscle aging, and a possible fix. By investigating how muscles adapt to age and disease-related decline, the scientists discovered the involvement of a druggable nuclear receptor, ERRγ, that could be targeted to preserve muscle function.

29 Sep 2026

Microplastics impair liver function and increase fat in mice

Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it.

29 Sep 2026

New study explains how TMEM63B protein regulates cell membranes

An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its inactive state under resting conditions, report researchers from Institute of Science Tokyo.

29 Sep 2026

New study uncovers breakthrough window to prevent brain metastasis

Metastasis, the process by which a tumor spreads throughout the body, is associated with the majority of cancer deaths.

29 Sep 2026

Scientists discover how excess dietary salt drives 'lean MASH'

Fatty liver disease is commonly associated with obesity, yet a growing number of people with normal body weight develop a severe form of the condition.

29 Sep 2026

Blood tests can identify cancer neoantigens for personalized immunotherapy

Cancer neoantigens and neoantigen-specific T cells were identified from patient blood samples by analyzing circulating tumor DNA (ctDNA) and immune cells, respectively, and they largely matched those found through traditional tumor tissue biopsy in many patients.

29 Sep 2026

Late diagnosis and systemic gaps drive high cancer death rates in the Balkans

In the Balkans, cancer survival rates lag due to late diagnoses and weak screening programs, highlighting the need for improved early detection strategies.

From BGI Genomics 29 Sep 2026

From espresso to filter coffee, brewing may shape what reaches your gut

A focused narrative review traces how caffeine, chlorogenic acids, and coffee fibers move through the gut and interact with microbes. The authors identify plausible links between the microbiome and liver health, but human studies have not shown that microbiome changes cause coffee’s reported metabolic benefits.

28 Sep 2026

Focused radiosurgery extends survival for small cell lung cancer patients with brain metastases

Patients with small cell lung cancer (SCLC) that had spread to the brain lived a median of 17 months after focused stereotactic radiosurgery, compared with nine months after an advanced form of whole brain radiation therapy, an unexpected secondary finding from the first randomized phase 3 trial to compare the treatment approaches in this population.

28 Sep 2026

Intentional substance exposures at school rise sharply among younger children

A new study found that rates of intentional substance exposures at school reported to U.S. poison centers increased substantially among elementary- and middle-school-aged children from 2000 through 2024, while high-school-aged adolescents continued to experience the highest rates of serious medical outcomes and hospital admissions.

28 Sep 2026

New study links human reaction times to breathing cycles

Imagine swimmers on starting blocks poised to dive at the sound of the starting horn or the driver of a car going 60 mph suddenly needing to brake to avoid a collision. A small fraction of a second in response time could make the difference between winning or losing and life or death.

28 Sep 2026

New antibody treatment blocks immune response to prevent Alzheimer's damage

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

28 Sep 2026

Zebrafish study reveals how albinism gene influences embryonic eye development

Tiny, striped zebrafish are helping scientists trace how a gene linked to albinism influences eye development, work that may ultimately help explain some of the vision problems experienced by people with the condition and guide the search for new treatments.

28 Sep 2026

Cancer cells erase sections of Y chromosome to trigger tumor growth in men

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

28 Sep 2026

Scientists find new way to overcome cell’s natural defenses against self-amplifying mRNA vaccines

The innovation could enable protection at lower doses, meaning vaccines could be rolled out further and faster than was previously imaginable, and opens new possibilities in gene therapy, cancer immunotherapy, and protein replacement therapies.

28 Sep 2026